Gene name: VPS75
Reference locus (S288C): YNL246W
Gene biotype: protein_coding
Description: Vacuolar protein sorting-associated protein 75; NAP family histone chaperone; binds to histones and Rtt109p, stimulating histone acetyltransferase activity; possesses nucleosome assembly activity in vitro; proposed role in vacuolar protein sorting and in double-strand break repair; protein abundance increases in response to DNA replication stress; relocalizes to the cytosol in response to hypoxia
Top 10 interactors (score): RTT109 (0.999); ASF1 (0.998); NAP1 (0.997); HHT1 (0.996); HHT2 (0.995); HTZ1 (0.972); RTT106 (0.968); HHF1 (0.929); CAC2 (0.925); GCN5 (0.917); HTA1 (0.911); POL30 (0.909); BUB3 (0.904); SUB2 (0.901); CEF1 (0.897); DUT1 (0.896); HTA2 (0.895); GPN3 (0.892); BRX1 (0.88); PRP19 (0.878)
Homologues (species, bitscore): seta (Danio rerio, 50.4); Set (Drosophila melanogaster, 69.7); NRP2 (Arabidopsis thaliana, 51.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:179245-180134:+ | gene-YNL246W_AKU4011 | rna-NM_001183084.1_AKU4011 | cds-NP_014153.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:83189-84078:+ | gene-YNL246W_BG1 | rna-NM_001183084.1_BG1 | cds-NP_014153.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:189052-189941:+ | gene-YNL246W_Bruggeman | rna-NM_001183084.1_Bruggeman | cds-NP_014153.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:196347-197236:+ | gene-YNL246W_CAT1 | rna-NM_001183084.1_CAT1 | cds-NP_014153.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:179642-180531:+ | gene-YNL246W_CBS1585 | rna-NM_001183084.1_CBS1585 | cds-NP_014153.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:174732-175621:+ | gene-YNL246W_CBS436 | rna-NM_001183084.1_CBS436 | cds-NP_014153.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:175683-176572:+ | gene-YNL246W_CBS6412 | rna-NM_001183084.1_CBS6412 | cds-NP_014153.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:176324-177213:+ | gene-YNL246W_CBS6413 | rna-NM_001183084.1_CBS6413 | cds-NP_014153.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:179271-180160:+ | gene-YNL246W_CENPK1137D | rna-NM_001183084.1_CENPK1137D | cds-NP_014153.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:176902-177791:+ | gene-YNL246W_EthanolRed | rna-NM_001183084.1_EthanolRed | cds-NP_014153.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:171637-172526:+ | gene-YNL246W_FaliES1 | rna-NM_001183084.1_FaliES1 | cds-NP_014153.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:82782-83671:+ | gene-YNL246W_JAY291 | rna-NM_001183084.1_JAY291 | cds-NP_014153.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:184835-185724:+ | gene-YNL246W_MUCL30387 | rna-NM_001183084.1_MUCL30387 | cds-NP_014153.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:183418-184307:+ | gene-YNL246W_MUCL30388 | rna-NM_001183084.1_MUCL30388 | cds-NP_014153.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:177132-178021:+ | gene-YNL246W_MUCL39482 | rna-NM_001183084.1_MUCL39482 | cds-NP_014153.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:179391-180280:+ | gene-YNL246W_MUCL42920 | rna-NM_001183084.1_MUCL42920 | cds-NP_014153.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:185429-186318:+ | gene-YNL246W_NCIM3186 | rna-NM_001183084.1_NCIM3186 | cds-NP_014153.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:179224-180113:+ | gene-YNL246W_NCYC1407 | rna-NM_001183084.1_NCYC1407 | cds-NP_014153.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:176125-177014:+ | gene-YNL246W_PE2H3 | rna-NM_001183084.1_PE2H3 | cds-NP_014153.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:175513-176402:+ | gene-YNL246W_PE2H4 | rna-NM_001183084.1_PE2H4 | cds-NP_014153.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:185460-186349:+ | gene-YNL246W_S288C | rna-NM_001183084.1_S288C | cds-NP_014153.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:65944-66833:- | gene-YNL246W_SA1 | rna-NM_001183084.1_SA1 | cds-NP_014153.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:172493-173382:+ | gene-YNL246W_ThermosaccDry | rna-NM_001183084.1_ThermosaccDry | cds-NP_014153.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:191382-192271:+ | gene-YNL246W_VR1 | rna-NM_001183084.1_VR1 | cds-NP_014153.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:82815-83704:+ | gene-YNL246W_ZTW1 | rna-NM_001183084.1_ZTW1 | cds-NP_014153.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:182751-183639:+ | gene-YNL246W_Sparadoxus | rna-NM_001183084.1_Sparadoxus | cds-NP_014153.1_Sparadoxus | 89.9 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |