Gene name: VPS60
Reference locus (S288C): YDR486C
Gene biotype: protein_coding
Description: Protein involved in late endosome to vacuole transport; cytoplasmic and vacuolar membrane protein; required for normal filament maturation during pseudohyphal growth; may function in targeting cargo proteins for degradation; interacts with Vta1p; Belongs to the SNF7 family
Top 10 interactors (score): VPS4 (0.999); DID4 (0.999); VTA1 (0.999); IST1 (0.999); DID2 (0.999); VPS24 (0.999); SNF7 (0.999); VPS20 (0.998); VPS25 (0.98); VPS28 (0.976); VPS36 (0.974); CHM7 (0.948); STP22 (0.941); MOH1 (0.91); ATG8 (0.9); DOA4 (0.822); BRO1 (0.796); MDM1 (0.787); RIB3 (0.773); MIM2 (0.766)
Homologues (species, bitscore): CHMP5 (Homo sapiens, 104.8); Chmp5 (Mus musculus, 104.4); chmp5b (Danio rerio, 99.8); chmp5 (Xenopus tropicalis, 88.6); Vps60 (Drosophila melanogaster, 107.5); F41E6.9 (Caenorhabditis elegans, 85.9); VPS60.1 (Arabidopsis thaliana, 84.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1367353-1368042:- | gene-YDR486C_AKU4011 | rna-NM_001180794.3_AKU4011 | cds-NP_010774.4_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000073.1:8963-9652:- | gene-YDR486C_BG1 | rna-NM_001180794.3_BG1 | cds-NP_010774.4_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1398758-1399447:- | gene-YDR486C_Bruggeman | rna-NM_001180794.3_Bruggeman | cds-NP_010774.4_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1375909-1376598:- | gene-YDR486C_CAT1 | rna-NM_001180794.3_CAT1 | cds-NP_010774.4_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1361652-1362341:- | gene-YDR486C_CBS1585 | rna-NM_001180794.3_CBS1585 | cds-NP_010774.4_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1381010-1381699:- | gene-YDR486C_CBS436 | rna-NM_001180794.3_CBS436 | cds-NP_010774.4_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1357276-1357965:- | gene-YDR486C_CBS6412 | rna-NM_001180794.3_CBS6412 | cds-NP_010774.4_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1380287-1380976:- | gene-YDR486C_CBS6413 | rna-NM_001180794.3_CBS6413 | cds-NP_010774.4_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1426127-1426816:- | gene-YDR486C_CENPK1137D | rna-NM_001180794.3_CENPK1137D | cds-NP_010774.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1370692-1371381:- | gene-YDR486C_EthanolRed | rna-NM_001180794.3_EthanolRed | cds-NP_010774.4_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1374245-1374934:- | gene-YDR486C_FaliES1 | rna-NM_001180794.3_FaliES1 | cds-NP_010774.4_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:72498-73187:- | gene-YDR486C_JAY291 | rna-NM_001180794.3_JAY291 | cds-NP_010774.4_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1381251-1381940:- | gene-YDR486C_MUCL30387 | rna-NM_001180794.3_MUCL30387 | cds-NP_010774.4_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1363276-1363965:- | gene-YDR486C_MUCL30388 | rna-NM_001180794.3_MUCL30388 | cds-NP_010774.4_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1353137-1353826:- | gene-YDR486C_MUCL39482 | rna-NM_001180794.3_MUCL39482 | cds-NP_010774.4_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1295926-1296615:- | gene-YDR486C_MUCL42920 | rna-NM_001180794.3_MUCL42920 | cds-NP_010774.4_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1427354-1428043:- | gene-YDR486C_NCIM3186 | rna-NM_001180794.3_NCIM3186 | cds-NP_010774.4_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1366906-1367595:- | gene-YDR486C_NCYC1407 | rna-NM_001180794.3_NCYC1407 | cds-NP_010774.4_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1377765-1378454:- | gene-YDR486C_PE2H3 | rna-NM_001180794.3_PE2H3 | cds-NP_010774.4_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1383339-1384028:- | gene-YDR486C_PE2H4 | rna-NM_001180794.3_PE2H4 | cds-NP_010774.4_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1427431-1428120:- | gene-YDR486C_S288C | rna-NM_001180794.3_S288C | cds-NP_010774.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:189026-189715:+ | gene-YDR486C_SA1 | rna-NM_001180794.3_SA1 | cds-NP_010774.4_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1378467-1379156:- | gene-YDR486C_ThermosaccDry | rna-NM_001180794.3_ThermosaccDry | cds-NP_010774.4_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1394210-1394899:- | gene-YDR486C_VR1 | rna-NM_001180794.3_VR1 | cds-NP_010774.4_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:421134-421823:- | gene-YDR486C_ZTW1 | rna-NM_001180794.3_ZTW1 | cds-NP_010774.4_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1381282-1381971:- | gene-YDR486C_Sparadoxus | rna-NM_001180794.3_Sparadoxus | cds-NP_010774.4_Sparadoxus | 91.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |