VPS45 (YGL095C)


Gene profile

Gene name: VPS45
Reference locus (S288C): YGL095C
Gene biotype: protein_coding

Description: Protein of the Sec1p/Munc-18 family; essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartment

Top 10 interactors (score): PEP7 (0.999); TLG2 (0.999); PEP12 (0.998); VTI1 (0.998); TLG1 (0.997); SEC1 (0.993); SED5 (0.991); VAM3 (0.99); PEP5 (0.988); YKT6 (0.987); SNC2 (0.986); VPS16 (0.985); PEP3 (0.982); SSO1 (0.981); SEC17 (0.973); VPS21 (0.967); VAM7 (0.967); VPS8 (0.966); SEC9 (0.957); SEC22 (0.947)

Homologues (species, bitscore): VPS45 (Homo sapiens, 366.7); Vps45 (Mus musculus, 369.0); vps45 (Danio rerio, 377.5); vps45 (Xenopus tropicalis, 252.7); Vps45 (Drosophila melanogaster, 345.9); vps-45 (Caenorhabditis elegans, 280.8); VPS45 (Arabidopsis thaliana, 340.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:331847-333580:- gene-YGL095C_AKU4011 rna-NM_001180960.3_AKU4011 cds-NP_011420.3_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000132.1:71804-73540:+ gene-YGL095C_BG1 rna-NM_001180960.3_BG1 cds-NP_011420.3_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:334339-336072:- gene-YGL095C_Bruggeman rna-NM_001180960.3_Bruggeman cds-NP_011420.3_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:331232-332965:- gene-YGL095C_CAT1 rna-NM_001180960.3_CAT1 cds-NP_011420.3_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:335172-336905:- gene-YGL095C_CBS1585 rna-NM_001180960.3_CBS1585 cds-NP_011420.3_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:329456-331189:- gene-YGL095C_CBS436 rna-NM_001180960.3_CBS436 cds-NP_011420.3_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:319553-321286:- gene-YGL095C_CBS6412 rna-NM_001180960.3_CBS6412 cds-NP_011420.3_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:329478-331211:- gene-YGL095C_CBS6413 rna-NM_001180960.3_CBS6413 cds-NP_011420.3_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:329061-330794:- gene-YGL095C_CENPK1137D rna-NM_001180960.3_CENPK1137D cds-NP_011420.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:320932-322665:- gene-YGL095C_EthanolRed rna-NM_001180960.3_EthanolRed cds-NP_011420.3_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:323493-325226:- gene-YGL095C_FaliES1 rna-NM_001180960.3_FaliES1 cds-NP_011420.3_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000369.1:9133-10869:- gene-YGL095C_JAY291 rna-NM_001180960.3_JAY291 cds-NP_011420.3_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:331316-333049:- gene-YGL095C_MUCL30387 rna-NM_001180960.3_MUCL30387 cds-NP_011420.3_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:334302-336035:- gene-YGL095C_MUCL30388 rna-NM_001180960.3_MUCL30388 cds-NP_011420.3_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:331700-333433:- gene-YGL095C_MUCL39482 rna-NM_001180960.3_MUCL39482 cds-NP_011420.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:336227-337960:- gene-YGL095C_MUCL42920 rna-NM_001180960.3_MUCL42920 cds-NP_011420.3_MUCL42920 99.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:328874-330607:- gene-YGL095C_NCIM3186 rna-NM_001180960.3_NCIM3186 cds-NP_011420.3_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:323235-324968:- gene-YGL095C_NCYC1407 rna-NM_001180960.3_NCYC1407 cds-NP_011420.3_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:324899-326635:- gene-YGL095C_PE2H3 rna-NM_001180960.3_PE2H3 cds-NP_011420.3_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:329899-331632:- gene-YGL095C_PE2H4 rna-NM_001180960.3_PE2H4 cds-NP_011420.3_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:328874-330607:- gene-YGL095C_S288C rna-NM_001180960.3_S288C cds-NP_011420.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000089.1:6256-7989:- gene-YGL095C_SA1 rna-NM_001180960.3_SA1 cds-NP_011420.3_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:323746-325479:- gene-YGL095C_ThermosaccDry rna-NM_001180960.3_ThermosaccDry cds-NP_011420.3_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:433607-435340:- gene-YGL095C_VR1 rna-NM_001180960.3_VR1 cds-NP_011420.3_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:321100-322833:- gene-YGL095C_ZTW1 rna-NM_001180960.3_ZTW1 cds-NP_011420.3_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:326825-328558:- gene-YGL095C_Sparadoxus rna-NM_001180960.3_Sparadoxus cds-NP_011420.3_Sparadoxus 90.1 100.0 Verified 1 1 1 False True False False False

Additional files