Gene name: VPS34
Reference locus (S288C): YLR240W
Gene biotype: protein_coding
Description: Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p; a fraction is localized, with Vps15p, to nuclear pores at nucleus-vacuole junctions and may facilitate transcription elongation for genes positioned at the nuclear periphery; Belongs to the PI3/PI4-kinase family
Top 10 interactors (score): VPS15 (0.999); ATG9 (0.999); VPS30 (0.999); VPS38 (0.999); ATG18 (0.999); ATG1 (0.999); ATG8 (0.999); ATG3 (0.998); ATG14 (0.998); ATG12 (0.997); FAB1 (0.997); ATG5 (0.995); ATG7 (0.994); ATG38 (0.994); ATG4 (0.992); ATG2 (0.992); ATG11 (0.988); VPS21 (0.985); LSB6 (0.982); SAC1 (0.981)
Homologues (species, bitscore): PIK3C3 (Homo sapiens, 535.8); Pik3c3 (Mus musculus, 525.0); pik3c3 (Danio rerio, 539.3); pik3c3 (Xenopus tropicalis, 507.3); Pi3K59F (Drosophila melanogaster, 489.2); vps-34 (Caenorhabditis elegans, 381.3); VPS34 (Arabidopsis thaliana, 490.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:571740-574367:+ | gene-YLR240W_AKU4011 | rna-NM_001182127.1_AKU4011 | cds-NP_013341.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000170.1:157541-160168:- | gene-YLR240W_BG1 | rna-NM_001182127.1_BG1 | cds-NP_013341.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:605978-608605:+ | gene-YLR240W_Bruggeman | rna-NM_001182127.1_Bruggeman | cds-NP_013341.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:605102-607729:+ | gene-YLR240W_CAT1 | rna-NM_001182127.1_CAT1 | cds-NP_013341.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:607235-609862:+ | gene-YLR240W_CBS1585 | rna-NM_001182127.1_CBS1585 | cds-NP_013341.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:591444-594071:+ | gene-YLR240W_CBS436 | rna-NM_001182127.1_CBS436 | cds-NP_013341.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:570210-572837:+ | gene-YLR240W_CBS6412 | rna-NM_001182127.1_CBS6412 | cds-NP_013341.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:607530-610157:+ | gene-YLR240W_CBS6413 | rna-NM_001182127.1_CBS6413 | cds-NP_013341.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:602144-604771:+ | gene-YLR240W_CENPK1137D | rna-NM_001182127.1_CENPK1137D | cds-NP_013341.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:565277-567904:+ | gene-YLR240W_EthanolRed | rna-NM_001182127.1_EthanolRed | cds-NP_013341.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:594202-596829:+ | gene-YLR240W_FaliES1 | rna-NM_001182127.1_FaliES1 | cds-NP_013341.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000136.1:62061-64688:- | gene-YLR240W_JAY291 | rna-NM_001182127.1_JAY291 | cds-NP_013341.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:606835-609462:+ | gene-YLR240W_MUCL30387 | rna-NM_001182127.1_MUCL30387 | cds-NP_013341.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:610957-613584:+ | gene-YLR240W_MUCL30388 | rna-NM_001182127.1_MUCL30388 | cds-NP_013341.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:608216-610843:+ | gene-YLR240W_MUCL39482 | rna-NM_001182127.1_MUCL39482 | cds-NP_013341.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:602978-605605:+ | gene-YLR240W_MUCL42920 | rna-NM_001182127.1_MUCL42920 | cds-NP_013341.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:617507-620134:+ | gene-YLR240W_NCIM3186 | rna-NM_001182127.1_NCIM3186 | cds-NP_013341.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:595205-597832:+ | gene-YLR240W_NCYC1407 | rna-NM_001182127.1_NCYC1407 | cds-NP_013341.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:598922-601549:+ | gene-YLR240W_PE2H3 | rna-NM_001182127.1_PE2H3 | cds-NP_013341.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:598666-601293:+ | gene-YLR240W_PE2H4 | rna-NM_001182127.1_PE2H4 | cds-NP_013341.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:617533-620160:+ | gene-YLR240W_S288C | rna-NM_001182127.1_S288C | cds-NP_013341.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:62312-64939:- | gene-YLR240W_SA1 | rna-NM_001182127.1_SA1 | cds-NP_013341.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:596702-599329:+ | gene-YLR240W_ThermosaccDry | rna-NM_001182127.1_ThermosaccDry | cds-NP_013341.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:608036-610663:+ | gene-YLR240W_VR1 | rna-NM_001182127.1_VR1 | cds-NP_013341.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:121018-123645:+ | gene-YLR240W_ZTW1 | rna-NM_001182127.1_ZTW1 | cds-NP_013341.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:582201-584828:+ | gene-YLR240W_Sparadoxus | rna-NM_001182127.1_Sparadoxus | cds-NP_013341.1_Sparadoxus | 92.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |