Gene name: VPS27
Reference locus (S288C): YNR006W
Gene biotype: protein_coding
Description: Hepatocyte growth factor-regulated tyrosine kinase substrate; Vacuolar protein sorting-associated protein 27; Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p)
Top 10 interactors (score): STP22 (0.999); UBI4 (0.999); HSE1 (0.999); VPS28 (0.998); VPS36 (0.998); EDE1 (0.997); VPS20 (0.997); SNF7 (0.997); VPS25 (0.995); VPS24 (0.993); DID4 (0.993); CHC1 (0.986); VPS5 (0.985); SNX3 (0.979); MVB12 (0.976); VPS4 (0.976); SNF8 (0.975); SRN2 (0.967); RSP5 (0.963); BRO1 (0.962)
Homologues (species, bitscore): HGS (Homo sapiens, 116.3); Hgs (Mus musculus, 115.9); hgs (Danio rerio, 118.6); hgs (Xenopus tropicalis, 114.8); Hrs (Drosophila melanogaster, 131.7); hgrs-1 (Caenorhabditis elegans, 123.6); AT1G61690 (Arabidopsis thaliana, 68.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:620568-622436:+ | gene-YNR006W_AKU4011 | rna-NM_001183183.3_AKU4011 | cds-NP_014403.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:528424-530292:+ | gene-YNR006W_BG1 | rna-NM_001183183.3_BG1 | cds-NP_014403.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:638061-639929:+ | gene-YNR006W_Bruggeman | rna-NM_001183183.3_Bruggeman | cds-NP_014403.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:672287-674155:+ | gene-YNR006W_CAT1 | rna-NM_001183183.3_CAT1 | cds-NP_014403.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:626364-628232:+ | gene-YNR006W_CBS1585 | rna-NM_001183183.3_CBS1585 | cds-NP_014403.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:688060-689928:+ | gene-YNR006W_CBS436 | rna-NM_001183183.3_CBS436 | cds-NP_014403.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:615930-617798:+ | gene-YNR006W_CBS6412 | rna-NM_001183183.3_CBS6412 | cds-NP_014403.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:617258-619126:+ | gene-YNR006W_CBS6413 | rna-NM_001183183.3_CBS6413 | cds-NP_014403.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:630672-632540:+ | gene-YNR006W_CENPK1137D | rna-NM_001183183.3_CENPK1137D | cds-NP_014403.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:622489-624357:+ | gene-YNR006W_EthanolRed | rna-NM_001183183.3_EthanolRed | cds-NP_014403.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:613507-615375:+ | gene-YNR006W_FaliES1 | rna-NM_001183183.3_FaliES1 | cds-NP_014403.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000037.1:87367-89235:- | gene-YNR006W_JAY291 | rna-NM_001183183.3_JAY291 | cds-NP_014403.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:635813-637681:+ | gene-YNR006W_MUCL30387 | rna-NM_001183183.3_MUCL30387 | cds-NP_014403.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:676647-678515:+ | gene-YNR006W_MUCL30388 | rna-NM_001183183.3_MUCL30388 | cds-NP_014403.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:617872-619740:+ | gene-YNR006W_MUCL39482 | rna-NM_001183183.3_MUCL39482 | cds-NP_014403.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:622056-623924:+ | gene-YNR006W_MUCL42920 | rna-NM_001183183.3_MUCL42920 | cds-NP_014403.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:636955-638823:+ | gene-YNR006W_NCIM3186 | rna-NM_001183183.3_NCIM3186 | cds-NP_014403.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:620374-622242:+ | gene-YNR006W_NCYC1407 | rna-NM_001183183.3_NCYC1407 | cds-NP_014403.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:621465-623333:+ | gene-YNR006W_PE2H3 | rna-NM_001183183.3_PE2H3 | cds-NP_014403.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:622783-624651:+ | gene-YNR006W_PE2H4 | rna-NM_001183183.3_PE2H4 | cds-NP_014403.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:636986-638854:+ | gene-YNR006W_S288C | rna-NM_001183183.3_S288C | cds-NP_014403.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000068.1:34690-36558:+ | gene-YNR006W_SA1 | rna-NM_001183183.3_SA1 | cds-NP_014403.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:613847-615715:+ | gene-YNR006W_ThermosaccDry | rna-NM_001183183.3_ThermosaccDry | cds-NP_014403.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:655810-657678:+ | gene-YNR006W_VR1 | rna-NM_001183183.3_VR1 | cds-NP_014403.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:522754-524622:+ | gene-YNR006W_ZTW1 | rna-NM_001183183.3_ZTW1 | cds-NP_014403.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:627875-629743:+ | gene-YNR006W_Sparadoxus | rna-NM_001183183.3_Sparadoxus | cds-NP_014403.3_Sparadoxus | 88.8 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |