Gene name: VPS15
Reference locus (S288C): YBR097W
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase VPS15; Serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p; myristoylated; a fraction is localized, with Vps34p, to nuclear pores at nucleus-vacuole junctions and may facilitate transcription elongation for genes positioned at the nuclear periphery
Top 10 interactors (score): ATG9 (0.999); VPS38 (0.999); VPS30 (0.999); VPS34 (0.999); ATG18 (0.998); ATG1 (0.998); ATG14 (0.998); ATG8 (0.997); ATG3 (0.996); ATG12 (0.996); ATG38 (0.996); FAB1 (0.992); ATG5 (0.991); ATG7 (0.991); ATG2 (0.99); ATG4 (0.981); ATG11 (0.979); ATG13 (0.974); GPA1 (0.962); YPT7 (0.931)
Homologues (species, bitscore): PIK3R4 (Homo sapiens, 443.0); Pik3r4 (Mus musculus, 437.2); pik3r4 (Danio rerio, 458.4); pik3r4 (Xenopus tropicalis, 452.2); ird1 (Drosophila melanogaster, 410.2); ZK930.1 (Caenorhabditis elegans, 263.8); VPS15 (Arabidopsis thaliana, 395.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:419314-423678:+ | gene-YBR097W_AKU4011 | rna-NM_001178445.2_AKU4011 | cds-NP_009655.2_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:410355-414719:+ | gene-YBR097W_BG1 | rna-NM_001178445.2_BG1 | cds-NP_009655.2_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:421092-425456:+ | gene-YBR097W_Bruggeman | rna-NM_001178445.2_Bruggeman | cds-NP_009655.2_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:423863-428227:+ | gene-YBR097W_CAT1 | rna-NM_001178445.2_CAT1 | cds-NP_009655.2_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:411599-415963:+ | gene-YBR097W_CBS1585 | rna-NM_001178445.2_CBS1585 | cds-NP_009655.2_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:419721-424085:+ | gene-YBR097W_CBS436 | rna-NM_001178445.2_CBS436 | cds-NP_009655.2_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:509827-514191:+ | gene-YBR097W_CBS6412 | rna-NM_001178445.2_CBS6412 | cds-NP_009655.2_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:416738-421102:+ | gene-YBR097W_CBS6413 | rna-NM_001178445.2_CBS6413 | cds-NP_009655.2_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:428851-433215:+ | gene-YBR097W_CENPK1137D | rna-NM_001178445.2_CENPK1137D | cds-NP_009655.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:546108-550472:+ | gene-YBR097W_EthanolRed | rna-NM_001178445.2_EthanolRed | cds-NP_009655.2_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:435391-439755:+ | gene-YBR097W_FaliES1 | rna-NM_001178445.2_FaliES1 | cds-NP_009655.2_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000312.1:6295-10659:+ | gene-YBR097W_JAY291 | rna-NM_001178445.2_JAY291 | cds-NP_009655.2_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:423126-427490:+ | gene-YBR097W_MUCL30387 | rna-NM_001178445.2_MUCL30387 | cds-NP_009655.2_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:422126-426490:+ | gene-YBR097W_MUCL30388 | rna-NM_001178445.2_MUCL30388 | cds-NP_009655.2_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:409742-414106:+ | gene-YBR097W_MUCL39482 | rna-NM_001178445.2_MUCL39482 | cds-NP_009655.2_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:418806-423170:+ | gene-YBR097W_MUCL42920 | rna-NM_001178445.2_MUCL42920 | cds-NP_009655.2_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:436748-441112:+ | gene-YBR097W_NCIM3186 | rna-NM_001178445.2_NCIM3186 | cds-NP_009655.2_NCIM3186 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:412521-416885:+ | gene-YBR097W_NCYC1407 | rna-NM_001178445.2_NCYC1407 | cds-NP_009655.2_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:425140-429504:+ | gene-YBR097W_PE2H3 | rna-NM_001178445.2_PE2H3 | cds-NP_009655.2_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:422816-427180:+ | gene-YBR097W_PE2H4 | rna-NM_001178445.2_PE2H4 | cds-NP_009655.2_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:436951-441315:+ | gene-YBR097W_S288C | rna-NM_001178445.2_S288C | cds-NP_009655.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000017.1:36393-40757:- | gene-YBR097W_SA1 | rna-NM_001178445.2_SA1 | cds-NP_009655.2_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:434398-438762:+ | gene-YBR097W_ThermosaccDry | rna-NM_001178445.2_ThermosaccDry | cds-NP_009655.2_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:416401-420765:+ | gene-YBR097W_VR1 | rna-NM_001178445.2_VR1 | cds-NP_009655.2_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:410061-414425:+ | gene-YBR097W_ZTW1 | rna-NM_001178445.2_ZTW1 | cds-NP_009655.2_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:446942-451306:+ | gene-YBR097W_Sparadoxus | rna-NM_001178445.2_Sparadoxus | cds-NP_009655.2_Sparadoxus | 89.6 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |