Gene name: VPS13
Reference locus (S288C): YLL040C
Gene biotype: protein_coding
Description: Vacuolar protein sorting-associated protein 13; Protein involved in prospore membrane morphogenesis; peripheral membrane protein that localizes to the prospore membrane and at numerous membrane contact sites; involved in sporulation, vacuolar protein sorting, prospore membrane formation during sporulation, and protein-Golgi retention; required for mitochondrial integrity; contains a PH-like domain; homologous to human CHAC and COH1 which are involved in Chorea-acanthocytosis and Cohen syndrome, respectively
Top 10 interactors (score): SPO71 (0.991); MCP1 (0.958); ATG2 (0.935); VPS35 (0.924); CDC31 (0.913); MDM10 (0.902); KEX2 (0.894); YPT35 (0.886); VID27 (0.821); PEP1 (0.816); ADP1 (0.813); TOM1 (0.776); MCP2 (0.772); SPO73 (0.766); MDM12 (0.755); YLL044W (0.745); LAM6 (0.745); ACC1 (0.734); SPO14 (0.728); YPT6 (0.723)
Homologues (species, bitscore): VPS13A (Homo sapiens, 515.8); Vps13a (Mus musculus, 495.4); vps13a (Danio rerio, 513.1); VPS13A (Xenopus tropicalis, 374.8); Vps13 (Drosophila melanogaster, 453.8); T08G11.1 (Caenorhabditis elegans, 424.9); AT4G17140 (Arabidopsis thaliana, 193.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:41367-50801:- | gene-YLL040C_AKU4011 | rna-NM_001181860.1_AKU4011 | cds-NP_013060.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:5309-14743:- | gene-YLL040C_BG1 | rna-NM_001181860.1_BG1 | cds-NP_013060.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:50711-60145:- | gene-YLL040C_Bruggeman | rna-NM_001181860.1_Bruggeman | cds-NP_013060.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:52244-61678:- | gene-YLL040C_CAT1 | rna-NM_001181860.1_CAT1 | cds-NP_013060.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:49274-58708:- | gene-YLL040C_CBS1585 | rna-NM_001181860.1_CBS1585 | cds-NP_013060.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:39268-48702:- | gene-YLL040C_CBS436 | rna-NM_001181860.1_CBS436 | cds-NP_013060.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:48936-58370:- | gene-YLL040C_CBS6412 | rna-NM_001181860.1_CBS6412 | cds-NP_013060.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:49063-58497:- | gene-YLL040C_CBS6413 | rna-NM_001181860.1_CBS6413 | cds-NP_013060.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:39191-48625:- | gene-YLL040C_CENPK1137D | rna-NM_001181860.1_CENPK1137D | cds-NP_013060.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:41989-51423:- | gene-YLL040C_EthanolRed | rna-NM_001181860.1_EthanolRed | cds-NP_013060.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:41302-50736:- | gene-YLL040C_FaliES1 | rna-NM_001181860.1_FaliES1 | cds-NP_013060.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000145.1:6313-15747:- | gene-YLL040C_JAY291 | rna-NM_001181860.1_JAY291 | cds-NP_013060.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:49009-58443:- | gene-YLL040C_MUCL30387 | rna-NM_001181860.1_MUCL30387 | cds-NP_013060.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:53003-62437:- | gene-YLL040C_MUCL30388 | rna-NM_001181860.1_MUCL30388 | cds-NP_013060.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:49277-58711:- | gene-YLL040C_MUCL39482 | rna-NM_001181860.1_MUCL39482 | cds-NP_013060.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:49582-59016:- | gene-YLL040C_MUCL42920 | rna-NM_001181860.1_MUCL42920 | cds-NP_013060.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:54185-63619:- | gene-YLL040C_NCIM3186 | rna-NM_001181860.1_NCIM3186 | cds-NP_013060.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:41142-50576:- | gene-YLL040C_NCYC1407 | rna-NM_001181860.1_NCYC1407 | cds-NP_013060.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:47829-57263:- | gene-YLL040C_PE2H3 | rna-NM_001181860.1_PE2H3 | cds-NP_013060.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:47637-57071:- | gene-YLL040C_PE2H4 | rna-NM_001181860.1_PE2H4 | cds-NP_013060.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:54211-63645:- | gene-YLL040C_S288C | rna-NM_001181860.1_S288C | cds-NP_013060.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000047.1:47504-56938:- | gene-YLL040C_SA1 | rna-NM_001181860.1_SA1 | cds-NP_013060.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:41808-51242:- | gene-YLL040C_ThermosaccDry | rna-NM_001181860.1_ThermosaccDry | cds-NP_013060.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:55405-64839:- | gene-YLL040C_VR1 | rna-NM_001181860.1_VR1 | cds-NP_013060.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:41132-50566:- | gene-YLL040C_ZTW1 | rna-NM_001181860.1_ZTW1 | cds-NP_013060.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:49755-59192:- | gene-YLL040C_Sparadoxus | rna-NM_001181860.1_Sparadoxus | cds-NP_013060.1_Sparadoxus | 90.6 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |