VPH2 (YKL119C)


Gene profile

Gene name: VPH2
Reference locus (S288C): YKL119C
Gene biotype: protein_coding

Description: Integral membrane protein required for V-ATPase function; not an actual component of the vacuolar H+-ATPase (V-ATPase) complex; functions in the assembly of the V-ATPase; localized to the endoplasmic reticulum (ER); involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner

Top 10 interactors (score): VMA22 (0.996); VPH1 (0.972); VMA21 (0.84); VMA6 (0.834); VMA5 (0.794); SSM4 (0.785); STV1 (0.784); VMA3 (0.734); VMA13 (0.716); YKL118W (0.713); DEG1 (0.71); VMA11 (0.707); SHR3 (0.671); APS3 (0.65); VMA1 (0.617); VMA8 (0.607); HRD1 (0.569); MATALPHA2 (0.569); HMLALPHA2 (0.567); VMA2 (0.562)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:205145-205792:- gene-YKL119C_AKU4011 rna-NM_001179685.1_AKU4011 cds-NP_012803.1_AKU4011 99.0 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:182267-182914:- gene-YKL119C_BG1 rna-NM_001179685.1_BG1 cds-NP_012803.1_BG1 98.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:223060-223707:- gene-YKL119C_Bruggeman rna-NM_001179685.1_Bruggeman cds-NP_012803.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:218113-218760:- gene-YKL119C_CAT1 rna-NM_001179685.1_CAT1 cds-NP_012803.1_CAT1 98.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:217378-218025:- gene-YKL119C_CBS1585 rna-NM_001179685.1_CBS1585 cds-NP_012803.1_CBS1585 99.0 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:215965-216612:- gene-YKL119C_CBS436 rna-NM_001179685.1_CBS436 cds-NP_012803.1_CBS436 98.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:202008-202655:- gene-YKL119C_CBS6412 rna-NM_001179685.1_CBS6412 cds-NP_012803.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:217841-218488:- gene-YKL119C_CBS6413 rna-NM_001179685.1_CBS6413 cds-NP_012803.1_CBS6413 99.0 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:218218-218865:- gene-YKL119C_CENPK1137D rna-NM_001179685.1_CENPK1137D cds-NP_012803.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:215877-216524:- gene-YKL119C_EthanolRed rna-NM_001179685.1_EthanolRed cds-NP_012803.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:216690-217337:- gene-YKL119C_FaliES1 rna-NM_001179685.1_FaliES1 cds-NP_012803.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000357.1:38983-39630:- gene-YKL119C_JAY291 rna-NM_001179685.1_JAY291 cds-NP_012803.1_JAY291 98.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:224881-225528:- gene-YKL119C_MUCL30387 rna-NM_001179685.1_MUCL30387 cds-NP_012803.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:219252-219899:- gene-YKL119C_MUCL30388 rna-NM_001179685.1_MUCL30388 cds-NP_012803.1_MUCL30388 99.0 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:217172-217819:- gene-YKL119C_MUCL39482 rna-NM_001179685.1_MUCL39482 cds-NP_012803.1_MUCL39482 98.9 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:221548-222195:- gene-YKL119C_MUCL42920 rna-NM_001179685.1_MUCL42920 cds-NP_012803.1_MUCL42920 99.0 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:218559-219206:- gene-YKL119C_NCIM3186 rna-NM_001179685.1_NCIM3186 cds-NP_012803.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:217354-218001:- gene-YKL119C_NCYC1407 rna-NM_001179685.1_NCYC1407 cds-NP_012803.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:224453-225100:- gene-YKL119C_PE2H3 rna-NM_001179685.1_PE2H3 cds-NP_012803.1_PE2H3 98.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:220737-221384:- gene-YKL119C_PE2H4 rna-NM_001179685.1_PE2H4 cds-NP_012803.1_PE2H4 99.0 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:218570-219217:- gene-YKL119C_S288C rna-NM_001179685.1_S288C cds-NP_012803.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:134693-135340:- gene-YKL119C_SA1 rna-NM_001179685.1_SA1 cds-NP_012803.1_SA1 98.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:217390-218037:- gene-YKL119C_ThermosaccDry rna-NM_001179685.1_ThermosaccDry cds-NP_012803.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:216704-217351:- gene-YKL119C_VR1 rna-NM_001179685.1_VR1 cds-NP_012803.1_VR1 98.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:215919-216566:- gene-YKL119C_ZTW1 rna-NM_001179685.1_ZTW1 cds-NP_012803.1_ZTW1 99.0 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:233192-233839:- gene-YKL119C_Sparadoxus rna-NM_001179685.1_Sparadoxus cds-NP_012803.1_Sparadoxus 90.8 100.0 Verified 1 1 1 False True False False False

Additional files