Gene name: VPH1
Reference locus (S288C): YOR270C
Gene biotype: protein_coding
Description: Subunit a of vacuolar-ATPase V0 domain; one of two isoforms (Vph1p and Stv1p); Vph1p is located in V-ATPase complexes of the vacuole while Stv1p is located in V-ATPase complexes of the Golgi and endosomes; relative distribution to the vacuolar membrane decreases upon DNA replication stress; human homolog ATP6V0A4 implicated in renal tubular acidosis, can complement yeast null mutant
Top 10 interactors (score): VMA6 (0.999); VMA10 (0.999); VMA4 (0.999); VMA5 (0.999); VMA8 (0.999); VMA2 (0.999); VMA3 (0.999); VMA1 (0.999); VMA7 (0.999); VMA13 (0.999); VMA11 (0.999); VMA16 (0.999); STV1 (0.995); VMA9 (0.993); VOA1 (0.975); VPH2 (0.972); VMA22 (0.971); RAV1 (0.97); PEP12 (0.94); VMA21 (0.925)
Homologues (species, bitscore): ATP6V0A1 (Homo sapiens, 632.9); Atp6v0a1 (Mus musculus, 644.0); atp6v0a1b (Danio rerio, 625.5); atp6v0a1 (Xenopus tropicalis, 629.4); Vha100-4 (Drosophila melanogaster, 621.3); unc-32 (Caenorhabditis elegans, 578.2); VHA-A3 (Arabidopsis thaliana, 542.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:818862-821384:- | gene-YOR270C_AKU4011 | rna-NM_001183689.3_AKU4011 | cds-NP_014913.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:220828-223350:- | gene-YOR270C_BG1 | rna-NM_001183689.3_BG1 | cds-NP_014913.3_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:804297-806819:- | gene-YOR270C_Bruggeman | rna-NM_001183689.3_Bruggeman | cds-NP_014913.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:804969-807491:- | gene-YOR270C_CAT1 | rna-NM_001183689.3_CAT1 | cds-NP_014913.3_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:801881-804403:- | gene-YOR270C_CBS1585 | rna-NM_001183689.3_CBS1585 | cds-NP_014913.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:800530-803052:- | gene-YOR270C_CBS436 | rna-NM_001183689.3_CBS436 | cds-NP_014913.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:798734-801256:- | gene-YOR270C_CBS6412 | rna-NM_001183689.3_CBS6412 | cds-NP_014913.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:807589-810111:- | gene-YOR270C_CBS6413 | rna-NM_001183689.3_CBS6413 | cds-NP_014913.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:827823-830345:- | gene-YOR270C_CENPK1137D | rna-NM_001183689.3_CENPK1137D | cds-NP_014913.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:794990-797512:- | gene-YOR270C_EthanolRed | rna-NM_001183689.3_EthanolRed | cds-NP_014913.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:800389-802911:- | gene-YOR270C_FaliES1 | rna-NM_001183689.3_FaliES1 | cds-NP_014913.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:24002-26524:+ | gene-YOR270C_JAY291 | rna-NM_001183689.3_JAY291 | cds-NP_014913.3_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:808534-811056:- | gene-YOR270C_MUCL30387 | rna-NM_001183689.3_MUCL30387 | cds-NP_014913.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:816510-819032:- | gene-YOR270C_MUCL30388 | rna-NM_001183689.3_MUCL30388 | cds-NP_014913.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:809226-811748:- | gene-YOR270C_MUCL39482 | rna-NM_001183689.3_MUCL39482 | cds-NP_014913.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:818714-821236:- | gene-YOR270C_MUCL42920 | rna-NM_001183689.3_MUCL42920 | cds-NP_014913.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:827941-830463:- | gene-YOR270C_NCIM3186 | rna-NM_001183689.3_NCIM3186 | cds-NP_014913.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:809432-811954:- | gene-YOR270C_NCYC1407 | rna-NM_001183689.3_NCYC1407 | cds-NP_014913.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:808510-811032:- | gene-YOR270C_PE2H3 | rna-NM_001183689.3_PE2H3 | cds-NP_014913.3_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:818887-821409:- | gene-YOR270C_PE2H4 | rna-NM_001183689.3_PE2H4 | cds-NP_014913.3_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:828052-830574:- | gene-YOR270C_S288C | rna-NM_001183689.3_S288C | cds-NP_014913.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:238071-240593:- | gene-YOR270C_SA1 | rna-NM_001183689.3_SA1 | cds-NP_014913.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:799572-802094:- | gene-YOR270C_ThermosaccDry | rna-NM_001183689.3_ThermosaccDry | cds-NP_014913.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:862950-865472:- | gene-YOR270C_VR1 | rna-NM_001183689.3_VR1 | cds-NP_014913.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:532460-534982:- | gene-YOR270C_ZTW1 | rna-NM_001183689.3_ZTW1 | cds-NP_014913.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:805195-807717:- | gene-YOR270C_Sparadoxus | rna-NM_001183689.3_Sparadoxus | cds-NP_014913.3_Sparadoxus | 93.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |