Gene name: VMA4
Reference locus (S288C): YOR332W
Gene biotype: protein_coding
Description: Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase); V-ATPase is an electrogenic proton pump found throughout the endomembrane system; V1 domain has eight subunits; required for the V1 domain to assemble onto the vacuolar membrane; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): VMA10 (0.999); VMA2 (0.999); VMA8 (0.999); VMA5 (0.999); VMA3 (0.999); VMA6 (0.999); VMA16 (0.999); VMA1 (0.999); VPH1 (0.999); VMA7 (0.999); VMA11 (0.999); STV1 (0.999); VMA13 (0.999); VMA9 (0.984); SGT2 (0.963); ATP1 (0.963); ATP2 (0.956); RAV1 (0.941); ATP15 (0.937); ATP5 (0.919)
Homologues (species, bitscore): ATP6V1E1 (Homo sapiens, 131.3); Atp6v1e2 (Mus musculus, 128.3); atp6v1e1a (Danio rerio, 134.0); atp6v1e1 (Xenopus tropicalis, 108.2); Vha26 (Drosophila melanogaster, 133.3); vha-8 (Caenorhabditis elegans, 136.7); VHA-E3 (Arabidopsis thaliana, 119.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:934153-934854:+ | gene-YOR332W_AKU4011 | rna-NM_001183752.3_AKU4011 | cds-NP_014977.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:336208-336909:+ | gene-YOR332W_BG1 | rna-NM_001183752.3_BG1 | cds-NP_014977.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:919560-920261:+ | gene-YOR332W_Bruggeman | rna-NM_001183752.3_Bruggeman | cds-NP_014977.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:920276-920977:+ | gene-YOR332W_CAT1 | rna-NM_001183752.3_CAT1 | cds-NP_014977.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:917976-918677:+ | gene-YOR332W_CBS1585 | rna-NM_001183752.3_CBS1585 | cds-NP_014977.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:915792-916493:+ | gene-YOR332W_CBS436 | rna-NM_001183752.3_CBS436 | cds-NP_014977.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:913686-914387:+ | gene-YOR332W_CBS6412 | rna-NM_001183752.3_CBS6412 | cds-NP_014977.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:922815-923516:+ | gene-YOR332W_CBS6413 | rna-NM_001183752.3_CBS6413 | cds-NP_014977.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:943431-944132:+ | gene-YOR332W_CENPK1137D | rna-NM_001183752.3_CENPK1137D | cds-NP_014977.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:910068-910769:+ | gene-YOR332W_EthanolRed | rna-NM_001183752.3_EthanolRed | cds-NP_014977.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:915691-916392:+ | gene-YOR332W_FaliES1 | rna-NM_001183752.3_FaliES1 | cds-NP_014977.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000078.1:86877-87578:- | gene-YOR332W_JAY291 | rna-NM_001183752.3_JAY291 | cds-NP_014977.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:924045-924746:+ | gene-YOR332W_MUCL30387 | rna-NM_001183752.3_MUCL30387 | cds-NP_014977.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:931817-932518:+ | gene-YOR332W_MUCL30388 | rna-NM_001183752.3_MUCL30388 | cds-NP_014977.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:924521-925222:+ | gene-YOR332W_MUCL39482 | rna-NM_001183752.3_MUCL39482 | cds-NP_014977.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:933975-934676:+ | gene-YOR332W_MUCL42920 | rna-NM_001183752.3_MUCL42920 | cds-NP_014977.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:943545-944246:+ | gene-YOR332W_NCIM3186 | rna-NM_001183752.3_NCIM3186 | cds-NP_014977.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:925521-926222:+ | gene-YOR332W_NCYC1407 | rna-NM_001183752.3_NCYC1407 | cds-NP_014977.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:923741-924442:+ | gene-YOR332W_PE2H3 | rna-NM_001183752.3_PE2H3 | cds-NP_014977.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:940093-940794:+ | gene-YOR332W_PE2H4 | rna-NM_001183752.3_PE2H4 | cds-NP_014977.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:943656-944357:+ | gene-YOR332W_S288C | rna-NM_001183752.3_S288C | cds-NP_014977.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000016.1:53984-54685:+ | gene-YOR332W_SA1 | rna-NM_001183752.3_SA1 | cds-NP_014977.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:914874-915575:+ | gene-YOR332W_ThermosaccDry | rna-NM_001183752.3_ThermosaccDry | cds-NP_014977.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:978161-978862:+ | gene-YOR332W_VR1 | rna-NM_001183752.3_VR1 | cds-NP_014977.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:647745-648446:+ | gene-YOR332W_ZTW1 | rna-NM_001183752.3_ZTW1 | cds-NP_014977.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:922122-922823:+ | gene-YOR332W_Sparadoxus | rna-NM_001183752.3_Sparadoxus | cds-NP_014977.3_Sparadoxus | 94.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |