Gene name: VMA2
Reference locus (S288C): YBR127C
Gene biotype: protein_coding
Description: V-type proton ATPase subunit B; Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase; electrogenic proton pump found throughout the endomembrane system; contains nucleotide binding sites; also detected in the cytoplasm; protein abundance increases in response to DNA replication stress; human homolog ATP6V1B1, implicated in autosomal-recessive distal renal tubular acidosis (RTA) with sensorineural deafness, complements yeast null mutant; Belongs to the ATPase alpha/beta chains family
Top 10 interactors (score): VMA8 (0.999); VMA4 (0.999); VMA10 (0.999); VMA5 (0.999); VMA3 (0.999); VMA6 (0.999); VMA16 (0.999); VMA1 (0.999); VMA13 (0.999); STV1 (0.999); VMA11 (0.999); VMA7 (0.999); VPH1 (0.999); RAV1 (0.982); VMA9 (0.98); ATP7 (0.965); ATP2 (0.96); ATP3 (0.956); GTR1 (0.954); ATP1 (0.938)
Homologues (species, bitscore): ATP6V1B2 (Homo sapiens, 796.6); Atp6v1b2 (Mus musculus, 798.5); atp6v1b2 (Danio rerio, 801.6); atp6v1b2 (Xenopus tropicalis, 790.8); Vha55 (Drosophila melanogaster, 792.0); vha-12 (Caenorhabditis elegans, 767.3); VAB1 (Arabidopsis thaliana, 752.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:474184-475737:- | gene-YBR127C_AKU4011 | rna-NM_001178475.3_AKU4011 | cds-NP_009685.3_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:464729-466282:- | gene-YBR127C_BG1 | rna-NM_001178475.3_BG1 | cds-NP_009685.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:475964-477517:- | gene-YBR127C_Bruggeman | rna-NM_001178475.3_Bruggeman | cds-NP_009685.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:479132-480685:- | gene-YBR127C_CAT1 | rna-NM_001178475.3_CAT1 | cds-NP_009685.3_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:465968-467521:- | gene-YBR127C_CBS1585 | rna-NM_001178475.3_CBS1585 | cds-NP_009685.3_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:474044-475597:- | gene-YBR127C_CBS436 | rna-NM_001178475.3_CBS436 | cds-NP_009685.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:563831-565384:- | gene-YBR127C_CBS6412 | rna-NM_001178475.3_CBS6412 | cds-NP_009685.3_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:471596-473149:- | gene-YBR127C_CBS6413 | rna-NM_001178475.3_CBS6413 | cds-NP_009685.3_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:485040-486593:- | gene-YBR127C_CENPK1137D | rna-NM_001178475.3_CENPK1137D | cds-NP_009685.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:600206-601759:- | gene-YBR127C_EthanolRed | rna-NM_001178475.3_EthanolRed | cds-NP_009685.3_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:490223-491776:- | gene-YBR127C_FaliES1 | rna-NM_001178475.3_FaliES1 | cds-NP_009685.3_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000444.1:13635-15188:- | gene-YBR127C_JAY291 | rna-NM_001178475.3_JAY291 | cds-NP_009685.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:478845-480398:- | gene-YBR127C_MUCL30387 | rna-NM_001178475.3_MUCL30387 | cds-NP_009685.3_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:477475-479028:- | gene-YBR127C_MUCL30388 | rna-NM_001178475.3_MUCL30388 | cds-NP_009685.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:464361-465914:- | gene-YBR127C_MUCL39482 | rna-NM_001178475.3_MUCL39482 | cds-NP_009685.3_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:474281-475834:- | gene-YBR127C_MUCL42920 | rna-NM_001178475.3_MUCL42920 | cds-NP_009685.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:491066-492619:- | gene-YBR127C_NCIM3186 | rna-NM_001178475.3_NCIM3186 | cds-NP_009685.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:466889-468442:- | gene-YBR127C_NCYC1407 | rna-NM_001178475.3_NCYC1407 | cds-NP_009685.3_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:479474-481027:- | gene-YBR127C_PE2H3 | rna-NM_001178475.3_PE2H3 | cds-NP_009685.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:477150-478703:- | gene-YBR127C_PE2H4 | rna-NM_001178475.3_PE2H4 | cds-NP_009685.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:491269-492822:- | gene-YBR127C_S288C | rna-NM_001178475.3_S288C | cds-NP_009685.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000032.1:12406-13959:- | gene-YBR127C_SA1 | rna-NM_001178475.3_SA1 | cds-NP_009685.3_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:489230-490783:- | gene-YBR127C_ThermosaccDry | rna-NM_001178475.3_ThermosaccDry | cds-NP_009685.3_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:470727-472280:- | gene-YBR127C_VR1 | rna-NM_001178475.3_VR1 | cds-NP_009685.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:464376-465929:- | gene-YBR127C_ZTW1 | rna-NM_001178475.3_ZTW1 | cds-NP_009685.3_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:501588-503141:- | gene-YBR127C_Sparadoxus | rna-NM_001178475.3_Sparadoxus | cds-NP_009685.3_Sparadoxus | 95.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |