Gene name: VMA1
Reference locus (S288C): YDL185W
Gene biotype: protein_coding
Description: Subunit A of the V1 peripheral membrane domain of V-ATPase; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease; the V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) has eight subunits; involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner; Belongs to the ATPase alpha/beta chains family
Top 10 interactors (score): VMA11 (0.999); STV1 (0.999); VMA13 (0.999); VMA16 (0.999); VMA4 (0.999); VMA10 (0.999); VMA6 (0.999); VMA2 (0.999); VMA8 (0.999); VMA7 (0.999); VPH1 (0.999); VMA3 (0.999); VMA5 (0.999); ATP2 (0.997); GTR1 (0.993); ATP3 (0.962); GTR2 (0.953); ATP1 (0.95); RAV1 (0.936); VPS41 (0.932)
Homologues (species, bitscore): ATP6V1A (Homo sapiens, 653.3); Atp6v1a (Mus musculus, 649.4); atp6v1ab (Danio rerio, 663.3); ENSXETP00000021824 (Xenopus tropicalis, 575.9); Vha68-2 (Drosophila melanogaster, 656.0); vha-13 (Caenorhabditis elegans, 651.7); VHA-A (Arabidopsis thaliana, 609.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:110786-114001:+ | gene-YDL185W_AKU4011 | rna-NM_001180245.1_AKU4011 | cds-NP_010096.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:435213-438428:- | gene-YDL185W_BG1 | rna-NM_001180245.1_BG1 | cds-NP_010096.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:127128-130343:+ | gene-YDL185W_Bruggeman | rna-NM_001180245.1_Bruggeman | cds-NP_010096.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | MBWC01000024.1:1-2683:- | gene-YDL185W_CAT1 | rna-NM_001180245.1_CAT1 | cds-NP_010096.1_CAT1 | 81.7 | 83.4 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:109335-112550:+ | gene-YDL185W_CBS1585 | rna-NM_001180245.1_CBS1585 | cds-NP_010096.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:126281-129496:+ | gene-YDL185W_CBS436 | rna-NM_001180245.1_CBS436 | cds-NP_010096.1_CBS436 | 98.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:109241-112456:+ | gene-YDL185W_CBS6412 | rna-NM_001180245.1_CBS6412 | cds-NP_010096.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:127211-130426:+ | gene-YDL185W_CBS6413 | rna-NM_001180245.1_CBS6413 | cds-NP_010096.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:125461-128676:+ | gene-YDL185W_CENPK1137D | rna-NM_001180245.1_CENPK1137D | cds-NP_010096.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:122924-126139:+ | gene-YDL185W_EthanolRed | rna-NM_001180245.1_EthanolRed | cds-NP_010096.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:128031-131246:+ | gene-YDL185W_FaliES1 | rna-NM_001180245.1_FaliES1 | cds-NP_010096.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000316.1:3736-6951:- | gene-YDL185W_JAY291 | rna-NM_001180245.1_JAY291 | cds-NP_010096.1_JAY291 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:125393-128608:+ | gene-YDL185W_MUCL30387 | rna-NM_001180245.1_MUCL30387 | cds-NP_010096.1_MUCL30387 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:115206-120504:+ | gene-YDL185W_MUCL30388 | rna-NM_001180245.1_MUCL30388 | cds-NP_010096.1_MUCL30388 | 60.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:110465-113680:+ | gene-YDL185W_MUCL39482 | rna-NM_001180245.1_MUCL39482 | cds-NP_010096.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:126549-129764:+ | gene-YDL185W_MUCL42920 | rna-NM_001180245.1_MUCL42920 | cds-NP_010096.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:126710-129925:+ | gene-YDL185W_NCIM3186 | rna-NM_001180245.1_NCIM3186 | cds-NP_010096.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:110117-113332:+ | gene-YDL185W_NCYC1407 | rna-NM_001180245.1_NCYC1407 | cds-NP_010096.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:117662-120877:+ | gene-YDL185W_PE2H3 | rna-NM_001180245.1_PE2H3 | cds-NP_010096.1_PE2H3 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:117666-120881:+ | gene-YDL185W_PE2H4 | rna-NM_001180245.1_PE2H4 | cds-NP_010096.1_PE2H4 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:126787-130002:+ | gene-YDL185W_S288C | rna-NM_001180245.1_S288C | cds-NP_010096.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000110.1:3863-7078:- | gene-YDL185W_SA1 | rna-NM_001180245.1_SA1 | cds-NP_010096.1_SA1 | 94.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:127790-131005:+ | gene-YDL185W_ThermosaccDry | rna-NM_001180245.1_ThermosaccDry | cds-NP_010096.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:128223-131438:+ | gene-YDL185W_VR1 | rna-NM_001180245.1_VR1 | cds-NP_010096.1_VR1 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:125963-129178:+ | gene-YDL185W_ZTW1 | rna-NM_001180245.1_ZTW1 | cds-NP_010096.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:129414-131267:+ | gene-YDL185W_Sparadoxus | rna-NM_001180245.1_Sparadoxus | cds-NP_010096.1_Sparadoxus | 55.3 | 57.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |