Gene name: VHS3
Reference locus (S288C): YOR054C
Gene biotype: protein_coding
Description: Phosphopantothenoylcysteine decarboxylase subunit VHS3; Negative regulatory subunit of protein phosphatase 1 Ppz1p; involved in coenzyme A biosynthesis; subunit of the phosphopantothenoylcysteine decarboxylase (PPCDC; Cab3p, Sis2p, Vhs3p) complex and the CoA-Synthesizing Protein Complex (CoA-SPC: Cab2p, Cab3p, Cab4p, Cab5p, Sis2p and Vhs3p)
Top 10 interactors (score): SIS2 (0.999); CAB3 (0.993); CAB4 (0.988); CAB5 (0.988); CAB2 (0.987); PPZ1 (0.985); PPZ2 (0.862); SIT4 (0.833); CAB1 (0.788); CDC21 (0.679); GLC8 (0.665); TRK2 (0.664); ENA1 (0.66); PPQ1 (0.611); YPI1 (0.597); GLC7 (0.573); NPY1 (0.527); TRK1 (0.516); FLO11 (0.469); CIR2 (0.468)
Homologues (species, bitscore): PPCDC (Homo sapiens, 120.9); Ppcdc (Mus musculus, 120.9); ppcdc (Danio rerio, 121.7); ppcdc (Xenopus tropicalis, 110.5); Ppcdc (Drosophila melanogaster, 105.5); F25H9.6 (Caenorhabditis elegans, 119.0); HAL3A (Arabidopsis thaliana, 131.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:412178-414199:- | gene-YOR054C_AKU4011 | rna-NM_001183473.1_AKU4011 | cds-NP_014697.1_AKU4011 | 99.6 | 99.8 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000124.1:1220-3181:- | gene-YOR054C_BG1 | rna-NM_001183473.1_BG1 | cds-NP_014697.1_BG1 | 96.1 | 96.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:414900-416897:- | gene-YOR054C_Bruggeman | rna-NM_001183473.1_Bruggeman | cds-NP_014697.1_Bruggeman | 98.4 | 98.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:413091-415088:- | gene-YOR054C_CAT1 | rna-NM_001183473.1_CAT1 | cds-NP_014697.1_CAT1 | 98.3 | 98.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:406869-408887:- | gene-YOR054C_CBS1585 | rna-NM_001183473.1_CBS1585 | cds-NP_014697.1_CBS1585 | 99.5 | 99.7 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:411223-413184:- | gene-YOR054C_CBS436 | rna-NM_001183473.1_CBS436 | cds-NP_014697.1_CBS436 | 96.0 | 96.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:406219-408216:- | gene-YOR054C_CBS6412 | rna-NM_001183473.1_CBS6412 | cds-NP_014697.1_CBS6412 | 98.4 | 98.6 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:413596-415590:- | gene-YOR054C_CBS6413 | rna-NM_001183473.1_CBS6413 | cds-NP_014697.1_CBS6413 | 98.3 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:427829-429853:- | gene-YOR054C_CENPK1137D | rna-NM_001183473.1_CENPK1137D | cds-NP_014697.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:408877-410910:- | gene-YOR054C_EthanolRed | rna-NM_001183473.1_EthanolRed | cds-NP_014697.1_EthanolRed | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:412220-414253:- | gene-YOR054C_FaliES1 | rna-NM_001183473.1_FaliES1 | cds-NP_014697.1_FaliES1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000035.1:82884-84878:- | gene-YOR054C_JAY291 | rna-NM_001183473.1_JAY291 | cds-NP_014697.1_JAY291 | 98.3 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:419696-421690:- | gene-YOR054C_MUCL30387 | rna-NM_001183473.1_MUCL30387 | cds-NP_014697.1_MUCL30387 | 98.2 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:424081-426105:- | gene-YOR054C_MUCL30388 | rna-NM_001183473.1_MUCL30388 | cds-NP_014697.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:414352-416370:- | gene-YOR054C_MUCL39482 | rna-NM_001183473.1_MUCL39482 | cds-NP_014697.1_MUCL39482 | 99.5 | 99.7 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:429178-431172:- | gene-YOR054C_MUCL42920 | rna-NM_001183473.1_MUCL42920 | cds-NP_014697.1_MUCL42920 | 98.2 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:427722-429746:- | gene-YOR054C_NCIM3186 | rna-NM_001183473.1_NCIM3186 | cds-NP_014697.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:421051-423060:- | gene-YOR054C_NCYC1407 | rna-NM_001183473.1_NCYC1407 | cds-NP_014697.1_NCYC1407 | 99.0 | 99.2 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:419909-421870:- | gene-YOR054C_PE2H3 | rna-NM_001183473.1_PE2H3 | cds-NP_014697.1_PE2H3 | 96.1 | 96.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:430290-432251:- | gene-YOR054C_PE2H4 | rna-NM_001183473.1_PE2H4 | cds-NP_014697.1_PE2H4 | 96.1 | 96.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:427833-429857:- | gene-YOR054C_S288C | rna-NM_001183473.1_S288C | cds-NP_014697.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:395776-397773:- | gene-YOR054C_SA1 | rna-NM_001183473.1_SA1 | cds-NP_014697.1_SA1 | 98.3 | 98.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:410760-412793:- | gene-YOR054C_ThermosaccDry | rna-NM_001183473.1_ThermosaccDry | cds-NP_014697.1_ThermosaccDry | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:412231-414189:- | gene-YOR054C_VR1 | rna-NM_001183473.1_VR1 | cds-NP_014697.1_VR1 | 96.1 | 96.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:145403-147406:- | gene-YOR054C_ZTW1 | rna-NM_001183473.1_ZTW1 | cds-NP_014697.1_ZTW1 | 98.8 | 98.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:418293-420275:- | gene-YOR054C_Sparadoxus | rna-NM_001183473.1_Sparadoxus | cds-NP_014697.1_Sparadoxus | 86.4 | 97.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |