Gene name: VHS2
Reference locus (S288C): YIL135C
Gene biotype: protein_coding
Description: Protein VHS2; Regulator of septin dynamics; involved in the regulation of septin dynamics at bud neck after mitotic entry, likely by stabilizing septin structure; regulated at post-translational level by cell cycle dependent phosphorylation; likely phosphorylated by Cdc28p and dephosphorylated by Cdc14p before cytokinesis; high-copy suppressor of synthetic lethality of sis2 sit4 double mutant; VHS2 has a paralog, MLF3, that arose from the whole genome duplication
Top 10 interactors (score): CUE4 (0.842); OAF1 (0.696); COS9 (0.692); YBR285W (0.691); GIC2 (0.629); YDR365W-A (0.617); YBR138C (0.612); AVT4 (0.612); DBF2 (0.602); LRE1 (0.572); SKG6 (0.57); PRM10 (0.559); TOS2 (0.529); MSA2 (0.521); AIM3 (0.499); WHI2 (0.495); PSR1 (0.495); CDC3 (0.467); ADD37 (0.454); BDF2 (0.45)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:96286-97596:- | gene-YIL135C_AKU4011 | rna-NM_001179483.1_AKU4011 | cds-NP_012131.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000174.1:39768-41078:+ | gene-YIL135C_BG1 | rna-NM_001179483.1_BG1 | cds-NP_012131.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:99041-100351:- | gene-YIL135C_Bruggeman | rna-NM_001179483.1_Bruggeman | cds-NP_012131.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:92853-94163:- | gene-YIL135C_CAT1 | rna-NM_001179483.1_CAT1 | cds-NP_012131.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:96488-97798:- | gene-YIL135C_CBS1585 | rna-NM_001179483.1_CBS1585 | cds-NP_012131.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:87626-88936:- | gene-YIL135C_CBS436 | rna-NM_001179483.1_CBS436 | cds-NP_012131.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:94019-95329:- | gene-YIL135C_CBS6412 | rna-NM_001179483.1_CBS6412 | cds-NP_012131.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:88174-89484:- | gene-YIL135C_CBS6413 | rna-NM_001179483.1_CBS6413 | cds-NP_012131.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:86773-88083:- | gene-YIL135C_CENPK1137D | rna-NM_001179483.1_CENPK1137D | cds-NP_012131.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:81822-83132:- | gene-YIL135C_EthanolRed | rna-NM_001179483.1_EthanolRed | cds-NP_012131.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:97625-98935:- | gene-YIL135C_FaliES1 | rna-NM_001179483.1_FaliES1 | cds-NP_012131.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000319.1:9421-10731:+ | gene-YIL135C_JAY291 | rna-NM_001179483.1_JAY291 | cds-NP_012131.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:96803-98113:- | gene-YIL135C_MUCL30387 | rna-NM_001179483.1_MUCL30387 | cds-NP_012131.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:96481-97791:- | gene-YIL135C_MUCL30388 | rna-NM_001179483.1_MUCL30388 | cds-NP_012131.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:97416-98726:- | gene-YIL135C_MUCL39482 | rna-NM_001179483.1_MUCL39482 | cds-NP_012131.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:100615-101925:- | gene-YIL135C_MUCL42920 | rna-NM_001179483.1_MUCL42920 | cds-NP_012131.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:95065-96375:- | gene-YIL135C_NCIM3186 | rna-NM_001179483.1_NCIM3186 | cds-NP_012131.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:101380-102690:- | gene-YIL135C_NCYC1407 | rna-NM_001179483.1_NCYC1407 | cds-NP_012131.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:96001-97311:- | gene-YIL135C_PE2H3 | rna-NM_001179483.1_PE2H3 | cds-NP_012131.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:89963-91273:- | gene-YIL135C_PE2H4 | rna-NM_001179483.1_PE2H4 | cds-NP_012131.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:95065-96375:- | gene-YIL135C_S288C | rna-NM_001179483.1_S288C | cds-NP_012131.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000050.1:73642-74952:- | gene-YIL135C_SA1 | rna-NM_001179483.1_SA1 | cds-NP_012131.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:96235-97545:- | gene-YIL135C_ThermosaccDry | rna-NM_001179483.1_ThermosaccDry | cds-NP_012131.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:93390-94700:- | gene-YIL135C_VR1 | rna-NM_001179483.1_VR1 | cds-NP_012131.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:71216-72526:- | gene-YIL135C_ZTW1 | rna-NM_001179483.1_ZTW1 | cds-NP_012131.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:89050-90357:- | gene-YIL135C_Sparadoxus | rna-NM_001179483.1_Sparadoxus | cds-NP_012131.1_Sparadoxus | 91.5 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |