Gene name: VHS1
Reference locus (S288C): YDR247W
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase VHS1; Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication
Top 10 interactors (score): SIP5 (0.835); PTC4 (0.76); FUS3 (0.701); YOR385W (0.631); PAA1 (0.613); KSS1 (0.589); YGK3 (0.563); HYM1 (0.562); SEF1 (0.562); CAK1 (0.547); SMK1 (0.546); NNK1 (0.543); SPS1 (0.542); STD1 (0.538); TPK3 (0.536); SDS24 (0.533); TPK1 (0.529); ECM25 (0.528); TPK2 (0.525); PUS9 (0.525)
Homologues (species, bitscore): MARK2 (Homo sapiens, 99.0); Mark2 (Mus musculus, 99.0); mark4a (Danio rerio, 100.1); mark3 (Xenopus tropicalis, 97.8); AMPKalpha (Drosophila melanogaster, 91.7); air-1 (Caenorhabditis elegans, 96.7); SIP4 (Arabidopsis thaliana, 109.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:912345-913730:+ | gene-YDR247W_AKU4011 | rna-NM_001180555.1_AKU4011 | cds-NP_010533.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:211578-212963:- | gene-YDR247W_BG1 | rna-NM_001180555.1_BG1 | cds-NP_010533.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:944673-946058:+ | gene-YDR247W_Bruggeman | rna-NM_001180555.1_Bruggeman | cds-NP_010533.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:931958-933343:+ | gene-YDR247W_CAT1 | rna-NM_001180555.1_CAT1 | cds-NP_010533.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:902694-904079:+ | gene-YDR247W_CBS1585 | rna-NM_001180555.1_CBS1585 | cds-NP_010533.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:932250-933635:+ | gene-YDR247W_CBS436 | rna-NM_001180555.1_CBS436 | cds-NP_010533.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:899454-900839:+ | gene-YDR247W_CBS6412 | rna-NM_001180555.1_CBS6412 | cds-NP_010533.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:930548-931933:+ | gene-YDR247W_CBS6413 | rna-NM_001180555.1_CBS6413 | cds-NP_010533.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:954940-956325:+ | gene-YDR247W_CENPK1137D | rna-NM_001180555.1_CENPK1137D | cds-NP_010533.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:913013-914398:+ | gene-YDR247W_EthanolRed | rna-NM_001180555.1_EthanolRed | cds-NP_010533.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:921215-922600:+ | gene-YDR247W_FaliES1 | rna-NM_001180555.1_FaliES1 | cds-NP_010533.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000261.1:9749-11131:+ | gene-YDR247W_JAY291 | rna-NM_001180555.1_JAY291 | cds-NP_010533.1_JAY291 | 99.6 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:930571-931956:+ | gene-YDR247W_MUCL30387 | rna-NM_001180555.1_MUCL30387 | cds-NP_010533.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:918601-919986:+ | gene-YDR247W_MUCL30388 | rna-NM_001180555.1_MUCL30388 | cds-NP_010533.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:904099-905484:+ | gene-YDR247W_MUCL39482 | rna-NM_001180555.1_MUCL39482 | cds-NP_010533.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:843861-845246:+ | gene-YDR247W_MUCL42920 | rna-NM_001180555.1_MUCL42920 | cds-NP_010533.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:955936-957321:+ | gene-YDR247W_NCIM3186 | rna-NM_001180555.1_NCIM3186 | cds-NP_010533.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:907768-909153:+ | gene-YDR247W_NCYC1407 | rna-NM_001180555.1_NCYC1407 | cds-NP_010533.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:924023-925408:+ | gene-YDR247W_PE2H3 | rna-NM_001180555.1_PE2H3 | cds-NP_010533.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:929300-930685:+ | gene-YDR247W_PE2H4 | rna-NM_001180555.1_PE2H4 | cds-NP_010533.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:956013-957398:+ | gene-YDR247W_S288C | rna-NM_001180555.1_S288C | cds-NP_010533.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:161860-163245:+ | gene-YDR247W_SA1 | rna-NM_001180555.1_SA1 | cds-NP_010533.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:919369-920754:+ | gene-YDR247W_ThermosaccDry | rna-NM_001180555.1_ThermosaccDry | cds-NP_010533.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:934622-936007:+ | gene-YDR247W_VR1 | rna-NM_001180555.1_VR1 | cds-NP_010533.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:182115-183500:+ | gene-YDR247W_ZTW1 | rna-NM_001180555.1_ZTW1 | cds-NP_010533.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:924765-926156:+ | gene-YDR247W_Sparadoxus | rna-NM_001180555.1_Sparadoxus | cds-NP_010533.1_Sparadoxus | 87.6 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |