Gene name: VHC1
Reference locus (S288C): YBR235W
Gene biotype: protein_coding
Description: Solute carrier family 12 (potassium/chloride transporters), member 9; Vacuolar membrane cation-chloride cotransporter (CCC); likely mediates K+ and Cl- cotransport into the vacuole; has a role in potassium homeostasis and salt tolerance; localizes to sites of contact between the vacuole and mitochondria (vCLAMPs); similar to mammalian electroneutral Na(+)-(K+)-C1- cotransporter family
Top 10 interactors (score): TRP3 (0.908); TRP1 (0.841); TRK2 (0.786); YPR003C (0.73); ENA1 (0.72); YNR029C (0.693); TRK1 (0.686); NST1 (0.676); YJL193W (0.66); SRP40 (0.654); YHL008C (0.619); PSK1 (0.592); PSK2 (0.592); MCH4 (0.586); GEF1 (0.57); SPG5 (0.562); ABD1 (0.557); SIP5 (0.554); NHA1 (0.547); REV3 (0.539)
Homologues (species, bitscore): SLC12A9 (Homo sapiens, 407.5); Slc12a9 (Mus musculus, 406.4); slc12a9 (Danio rerio, 464.9); ENSXETP00000061390 (Xenopus tropicalis, 386.7); CG10413 (Drosophila melanogaster, 392.1); T04B8.5 (Caenorhabditis elegans, 419.5); CCC1 (Arabidopsis thaliana, 238.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:671208-674570:+ | gene-YBR235W_AKU4011 | rna-NM_001178583.3_AKU4011 | cds-NP_009794.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000066.1:42171-45533:+ | gene-YBR235W_BG1 | rna-NM_001178583.3_BG1 | cds-NP_009794.3_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:672363-675725:+ | gene-YBR235W_Bruggeman | rna-NM_001178583.3_Bruggeman | cds-NP_009794.3_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:675569-678931:+ | gene-YBR235W_CAT1 | rna-NM_001178583.3_CAT1 | cds-NP_009794.3_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:662740-666102:+ | gene-YBR235W_CBS1585 | rna-NM_001178583.3_CBS1585 | cds-NP_009794.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:669165-672527:+ | gene-YBR235W_CBS436 | rna-NM_001178583.3_CBS436 | cds-NP_009794.3_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:757720-761082:+ | gene-YBR235W_CBS6412 | rna-NM_001178583.3_CBS6412 | cds-NP_009794.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:668783-672145:+ | gene-YBR235W_CBS6413 | rna-NM_001178583.3_CBS6413 | cds-NP_009794.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:680678-684040:+ | gene-YBR235W_CENPK1137D | rna-NM_001178583.3_CENPK1137D | cds-NP_009794.3_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:794449-797811:+ | gene-YBR235W_EthanolRed | rna-NM_001178583.3_EthanolRed | cds-NP_009794.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:687556-690918:+ | gene-YBR235W_FaliES1 | rna-NM_001178583.3_FaliES1 | cds-NP_009794.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000067.1:111432-114794:- | gene-YBR235W_JAY291 | rna-NM_001178583.3_JAY291 | cds-NP_009794.3_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:674379-677741:+ | gene-YBR235W_MUCL30387 | rna-NM_001178583.3_MUCL30387 | cds-NP_009794.3_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:691458-694820:+ | gene-YBR235W_MUCL30388 | rna-NM_001178583.3_MUCL30388 | cds-NP_009794.3_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:661092-664454:+ | gene-YBR235W_MUCL39482 | rna-NM_001178583.3_MUCL39482 | cds-NP_009794.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:670941-674303:+ | gene-YBR235W_MUCL42920 | rna-NM_001178583.3_MUCL42920 | cds-NP_009794.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:686698-690060:+ | gene-YBR235W_NCIM3186 | rna-NM_001178583.3_NCIM3186 | cds-NP_009794.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:662955-666317:+ | gene-YBR235W_NCYC1407 | rna-NM_001178583.3_NCYC1407 | cds-NP_009794.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:686071-689433:+ | gene-YBR235W_PE2H3 | rna-NM_001178583.3_PE2H3 | cds-NP_009794.3_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:683747-687109:+ | gene-YBR235W_PE2H4 | rna-NM_001178583.3_PE2H4 | cds-NP_009794.3_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:686901-690263:+ | gene-YBR235W_S288C | rna-NM_001178583.3_S288C | cds-NP_009794.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000019.1:42028-45390:+ | gene-YBR235W_SA1 | rna-NM_001178583.3_SA1 | cds-NP_009794.3_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:686566-689928:+ | gene-YBR235W_ThermosaccDry | rna-NM_001178583.3_ThermosaccDry | cds-NP_009794.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:666745-670107:+ | gene-YBR235W_VR1 | rna-NM_001178583.3_VR1 | cds-NP_009794.3_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:659429-662791:+ | gene-YBR235W_ZTW1 | rna-NM_001178583.3_ZTW1 | cds-NP_009794.3_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:703430-706780:+ | gene-YBR235W_Sparadoxus | rna-NM_001178583.3_Sparadoxus | cds-NP_009794.3_Sparadoxus | 90.1 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |