VFA1 (YER128W)


Gene profile

Gene name: VFA1
Reference locus (S288C): YER128W
Gene biotype: protein_coding

Description: VPS4-associated protein 1; Protein that interacts with Vps4p and has a role in vacuolar sorting; stimulates the ATPase activity of Vps4; localizes to endosomes in a Vps4-dependent manner; overexpression causes canavanine sensitivity and confers a partial class D vacuole morphology

Top 10 interactors (score): VPS4 (0.959); MIM2 (0.749); IST1 (0.713); EMP70 (0.694); VAB2 (0.692); RCR1 (0.69); VTA1 (0.645); PFA3 (0.611); IVY1 (0.61); GYP5 (0.572); MIM1 (0.529); PKR1 (0.526); VMA21 (0.522); YIP5 (0.521); VMA22 (0.497); SYN8 (0.489); VPS3 (0.482); VMA16 (0.481); VMA5 (0.45)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:409735-410346:+ gene-YER128W_AKU4011 rna-NM_001179018.3_AKU4011 cds-NP_011054.3_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:15308-15919:- gene-YER128W_BG1 rna-NM_001179018.3_BG1 cds-NP_011054.3_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:420201-420812:+ gene-YER128W_Bruggeman rna-NM_001179018.3_Bruggeman cds-NP_011054.3_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:415442-416053:+ gene-YER128W_CAT1 rna-NM_001179018.3_CAT1 cds-NP_011054.3_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:409130-409741:+ gene-YER128W_CBS1585 rna-NM_001179018.3_CBS1585 cds-NP_011054.3_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:411835-412446:+ gene-YER128W_CBS436 rna-NM_001179018.3_CBS436 cds-NP_011054.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:408208-408819:+ gene-YER128W_CBS6412 rna-NM_001179018.3_CBS6412 cds-NP_011054.3_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:415051-415662:+ gene-YER128W_CBS6413 rna-NM_001179018.3_CBS6413 cds-NP_011054.3_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:413623-414234:+ gene-YER128W_CENPK1137D rna-NM_001179018.3_CENPK1137D cds-NP_011054.3_CENPK1137D 99.8 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:409579-410190:+ gene-YER128W_EthanolRed rna-NM_001179018.3_EthanolRed cds-NP_011054.3_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:410060-410671:+ gene-YER128W_FaliES1 rna-NM_001179018.3_FaliES1 cds-NP_011054.3_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000028.1:18282-18893:+ gene-YER128W_JAY291 rna-NM_001179018.3_JAY291 cds-NP_011054.3_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:417150-417761:+ gene-YER128W_MUCL30387 rna-NM_001179018.3_MUCL30387 cds-NP_011054.3_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:412096-412707:+ gene-YER128W_MUCL30388 rna-NM_001179018.3_MUCL30388 cds-NP_011054.3_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:408155-408766:+ gene-YER128W_MUCL39482 rna-NM_001179018.3_MUCL39482 cds-NP_011054.3_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:416642-417253:+ gene-YER128W_MUCL42920 rna-NM_001179018.3_MUCL42920 cds-NP_011054.3_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:415858-416469:+ gene-YER128W_NCIM3186 rna-NM_001179018.3_NCIM3186 cds-NP_011054.3_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:413688-414299:+ gene-YER128W_NCYC1407 rna-NM_001179018.3_NCYC1407 cds-NP_011054.3_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:424233-424844:+ gene-YER128W_PE2H3 rna-NM_001179018.3_PE2H3 cds-NP_011054.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:414174-414785:+ gene-YER128W_PE2H4 rna-NM_001179018.3_PE2H4 cds-NP_011054.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:415859-416470:+ gene-YER128W_S288C rna-NM_001179018.3_S288C cds-NP_011054.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000023.1:125459-126070:+ gene-YER128W_SA1 rna-NM_001179018.3_SA1 cds-NP_011054.3_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:410858-411469:+ gene-YER128W_ThermosaccDry rna-NM_001179018.3_ThermosaccDry cds-NP_011054.3_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:411910-412521:+ gene-YER128W_VR1 rna-NM_001179018.3_VR1 cds-NP_011054.3_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:407987-408598:+ gene-YER128W_ZTW1 rna-NM_001179018.3_ZTW1 cds-NP_011054.3_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:411795-412409:+ gene-YER128W_Sparadoxus rna-NM_001179018.3_Sparadoxus cds-NP_011054.3_Sparadoxus 88.4 100.0 Verified 1 1 1 False True False False False

Additional files