VAS1 (YGR094W)


Gene profile

Gene name: VAS1
Reference locus (S288C): YGR094W
Gene biotype: protein_coding

Description: Valine--tRNA ligase, mitochondrial; Mitochondrial and cytoplasmic valyl-tRNA synthetase; human homolog VARS2 implicated in mitochondrial diseases, can partially complement yeast null mutant

Top 10 interactors (score): CDC60 (0.999); ILS1 (0.998); GLN4 (0.998); GUS1 (0.997); HTS1 (0.993); TEF4 (0.991); CAM1 (0.988); THS1 (0.988); GRS1 (0.987); ALA1 (0.982); FRS2 (0.968); MSF1 (0.96); ARC1 (0.956); KRS1 (0.956); DED81 (0.948); MES1 (0.933); TYS1 (0.922); YDR341C (0.922); MST1 (0.921); YNL247W (0.906)

Homologues (species, bitscore): VARS (Homo sapiens, 1027.7); Vars (Mus musculus, 1029.2); vars (Danio rerio, 1018.1); vars (Xenopus tropicalis, 944.1); Aats-val (Drosophila melanogaster, 1059.7); vars-2 (Caenorhabditis elegans, 976.1); TWN2 (Arabidopsis thaliana, 946.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:656366-659680:+ gene-YGR094W_AKU4011 rna-NM_001181223.1_AKU4011 cds-NP_011608.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000173.1:92173-95487:+ gene-YGR094W_BG1 rna-NM_001181223.1_BG1 cds-NP_011608.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:658556-661870:+ gene-YGR094W_Bruggeman rna-NM_001181223.1_Bruggeman cds-NP_011608.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:656746-660060:+ gene-YGR094W_CAT1 rna-NM_001181223.1_CAT1 cds-NP_011608.1_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:657330-660644:+ gene-YGR094W_CBS1585 rna-NM_001181223.1_CBS1585 cds-NP_011608.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:658990-662304:+ gene-YGR094W_CBS436 rna-NM_001181223.1_CBS436 cds-NP_011608.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:649023-652337:+ gene-YGR094W_CBS6412 rna-NM_001181223.1_CBS6412 cds-NP_011608.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:653965-657279:+ gene-YGR094W_CBS6413 rna-NM_001181223.1_CBS6413 cds-NP_011608.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:671863-675177:+ gene-YGR094W_CENPK1137D rna-NM_001181223.1_CENPK1137D cds-NP_011608.1_CENPK1137D 99.4 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:643917-647231:+ gene-YGR094W_EthanolRed rna-NM_001181223.1_EthanolRed cds-NP_011608.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:647762-651076:+ gene-YGR094W_FaliES1 rna-NM_001181223.1_FaliES1 cds-NP_011608.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000396.1:25478-28792:- gene-YGR094W_JAY291 rna-NM_001181223.1_JAY291 cds-NP_011608.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:655544-658858:+ gene-YGR094W_MUCL30387 rna-NM_001181223.1_MUCL30387 cds-NP_011608.1_MUCL30387 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:658356-661670:+ gene-YGR094W_MUCL30388 rna-NM_001181223.1_MUCL30388 cds-NP_011608.1_MUCL30388 99.9 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:653058-656372:+ gene-YGR094W_MUCL39482 rna-NM_001181223.1_MUCL39482 cds-NP_011608.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:663368-666682:+ gene-YGR094W_MUCL42920 rna-NM_001181223.1_MUCL42920 cds-NP_011608.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:672186-675500:+ gene-YGR094W_NCIM3186 rna-NM_001181223.1_NCIM3186 cds-NP_011608.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:647747-651061:+ gene-YGR094W_NCYC1407 rna-NM_001181223.1_NCYC1407 cds-NP_011608.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:650436-653750:+ gene-YGR094W_PE2H3 rna-NM_001181223.1_PE2H3 cds-NP_011608.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:655556-658870:+ gene-YGR094W_PE2H4 rna-NM_001181223.1_PE2H4 cds-NP_011608.1_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:672186-675500:+ gene-YGR094W_S288C rna-NM_001181223.1_S288C cds-NP_011608.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000015.1:98760-102074:+ gene-YGR094W_SA1 rna-NM_001181223.1_SA1 cds-NP_011608.1_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:668132-671446:+ gene-YGR094W_ThermosaccDry rna-NM_001181223.1_ThermosaccDry cds-NP_011608.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:764626-767940:+ gene-YGR094W_VR1 rna-NM_001181223.1_VR1 cds-NP_011608.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000015.1:122382-125696:+ gene-YGR094W_ZTW1 rna-NM_001181223.1_ZTW1 cds-NP_011608.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:658184-661498:+ gene-YGR094W_Sparadoxus rna-NM_001181223.1_Sparadoxus cds-NP_011608.1_Sparadoxus 92.9 100.0 Verified 1 1 1 False True False False False

Additional files