Gene name: USB1
Reference locus (S288C): YLR132C
Gene biotype: protein_coding
Description: U6 snRNA phosphodiesterase; Putative poly(U)-specific 3'-to-5' RNA exonuclease; involved in 3'-end processing of U6 snRNA removing uridines and generating a terminal 2′,3′ cyclic phosphate; essential protein that localizes to the nucleus and mitochondria; overexpression suppresses the respiratory defects of oxa1 and mtf2 mutants; homolog of S.pombe gene, mpn1 and human gene, hUSB1; mutations in hUSB1 are associated with a rare genodermatosis, poikiloderma with neutropenia (OMIM 604173); Belongs to the 2H phosphoesterase superfamily. USB1 family
Top 10 interactors (score): QCR2 (0.833); PRP19 (0.763); COR1 (0.73); MTF2 (0.684); MMT2 (0.676); RMD9 (0.67); BCS1 (0.574); RBS1 (0.569); MHT1 (0.568); MOG1 (0.567); LSM8 (0.506); BIO4 (0.499); ORT1 (0.497); YJU2 (0.497); CWC22 (0.495); OXA1 (0.488); ARG2 (0.483); WSC4 (0.483); VHR1 (0.481); BIO5 (0.479)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:389762-390634:- | gene-YLR132C_AKU4011 | rna-NM_001182019.1_AKU4011 | cds-NP_013233.1_AKU4011 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:353547-354419:- | gene-YLR132C_BG1 | rna-NM_001182019.1_BG1 | cds-NP_013233.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:401645-402517:- | gene-YLR132C_Bruggeman | rna-NM_001182019.1_Bruggeman | cds-NP_013233.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:401056-401928:- | gene-YLR132C_CAT1 | rna-NM_001182019.1_CAT1 | cds-NP_013233.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:396906-397778:- | gene-YLR132C_CBS1585 | rna-NM_001182019.1_CBS1585 | cds-NP_013233.1_CBS1585 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:387147-388019:- | gene-YLR132C_CBS436 | rna-NM_001182019.1_CBS436 | cds-NP_013233.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:395323-396195:- | gene-YLR132C_CBS6412 | rna-NM_001182019.1_CBS6412 | cds-NP_013233.1_CBS6412 | 98.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:397171-398043:- | gene-YLR132C_CBS6413 | rna-NM_001182019.1_CBS6413 | cds-NP_013233.1_CBS6413 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:392305-393177:- | gene-YLR132C_CENPK1137D | rna-NM_001182019.1_CENPK1137D | cds-NP_013233.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:389963-390835:- | gene-YLR132C_EthanolRed | rna-NM_001182019.1_EthanolRed | cds-NP_013233.1_EthanolRed | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:389474-390346:- | gene-YLR132C_FaliES1 | rna-NM_001182019.1_FaliES1 | cds-NP_013233.1_FaliES1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000117.1:2844-3716:+ | gene-YLR132C_JAY291 | rna-NM_001182019.1_JAY291 | cds-NP_013233.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:401637-402509:- | gene-YLR132C_MUCL30387 | rna-NM_001182019.1_MUCL30387 | cds-NP_013233.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:406456-407328:- | gene-YLR132C_MUCL30388 | rna-NM_001182019.1_MUCL30388 | cds-NP_013233.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:397415-398287:- | gene-YLR132C_MUCL39482 | rna-NM_001182019.1_MUCL39482 | cds-NP_013233.1_MUCL39482 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:397545-398417:- | gene-YLR132C_MUCL42920 | rna-NM_001182019.1_MUCL42920 | cds-NP_013233.1_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:407257-408129:- | gene-YLR132C_NCIM3186 | rna-NM_001182019.1_NCIM3186 | cds-NP_013233.1_NCIM3186 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:389687-390559:- | gene-YLR132C_NCYC1407 | rna-NM_001182019.1_NCYC1407 | cds-NP_013233.1_NCYC1407 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:395257-396129:- | gene-YLR132C_PE2H3 | rna-NM_001182019.1_PE2H3 | cds-NP_013233.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:394998-395870:- | gene-YLR132C_PE2H4 | rna-NM_001182019.1_PE2H4 | cds-NP_013233.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:407283-408155:- | gene-YLR132C_S288C | rna-NM_001182019.1_S288C | cds-NP_013233.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000055.1:33194-34066:- | gene-YLR132C_SA1 | rna-NM_001182019.1_SA1 | cds-NP_013233.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:390684-391556:- | gene-YLR132C_ThermosaccDry | rna-NM_001182019.1_ThermosaccDry | cds-NP_013233.1_ThermosaccDry | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:403398-404270:- | gene-YLR132C_VR1 | rna-NM_001182019.1_VR1 | cds-NP_013233.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:388482-389354:- | gene-YLR132C_ZTW1 | rna-NM_001182019.1_ZTW1 | cds-NP_013233.1_ZTW1 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:398584-399456:- | gene-YLR132C_Sparadoxus | rna-NM_001182019.1_Sparadoxus | cds-NP_013233.1_Sparadoxus | 88.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |