Gene name: URE2
Reference locus (S288C): YNL229C
Gene biotype: protein_coding
Description: Nitrogen catabolite repression transcriptional regulator; inhibits GLN3 transcription in good nitrogen source; role in sequestering Gln3p and Gat1p to the cytoplasm; has glutathione peroxidase activity and can mutate to acquire GST activity; self-assembly under limited nitrogen conditions creates [URE3] prion and releases catabolite repression
Top 10 interactors (score): GLN3 (0.999); GLR1 (0.98); SUP35 (0.979); YDJ1 (0.977); HSP104 (0.965); SSA1 (0.964); RNQ1 (0.959); GTT1 (0.955); PRX1 (0.948); SWI1 (0.935); NEW1 (0.932); ECM38 (0.929); GSH2 (0.927); DAL80 (0.925); GAT1 (0.92); PRC1 (0.919); YBR139W (0.913); YCF1 (0.909); SIS1 (0.903); YBT1 (0.902)
Homologues (species, bitscore): GstD3 (Drosophila melanogaster, 70.5); GSTF9 (Arabidopsis thaliana, 68.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:212916-213980:- | gene-YNL229C_AKU4011 | rna-NM_001183067.1_AKU4011 | cds-NP_014170.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:116861-117925:- | gene-YNL229C_BG1 | rna-NM_001183067.1_BG1 | cds-NP_014170.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:222967-224031:- | gene-YNL229C_Bruggeman | rna-NM_001183067.1_Bruggeman | cds-NP_014170.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:230123-231187:- | gene-YNL229C_CAT1 | rna-NM_001183067.1_CAT1 | cds-NP_014170.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:213313-214377:- | gene-YNL229C_CBS1585 | rna-NM_001183067.1_CBS1585 | cds-NP_014170.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:208399-209463:- | gene-YNL229C_CBS436 | rna-NM_001183067.1_CBS436 | cds-NP_014170.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:209347-210411:- | gene-YNL229C_CBS6412 | rna-NM_001183067.1_CBS6412 | cds-NP_014170.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:209995-211059:- | gene-YNL229C_CBS6413 | rna-NM_001183067.1_CBS6413 | cds-NP_014170.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:212945-214009:- | gene-YNL229C_CENPK1137D | rna-NM_001183067.1_CENPK1137D | cds-NP_014170.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:210566-211630:- | gene-YNL229C_EthanolRed | rna-NM_001183067.1_EthanolRed | cds-NP_014170.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:205308-206372:- | gene-YNL229C_FaliES1 | rna-NM_001183067.1_FaliES1 | cds-NP_014170.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:116453-117517:- | gene-YNL229C_JAY291 | rna-NM_001183067.1_JAY291 | cds-NP_014170.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:218501-219565:- | gene-YNL229C_MUCL30387 | rna-NM_001183067.1_MUCL30387 | cds-NP_014170.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:217086-218150:- | gene-YNL229C_MUCL30388 | rna-NM_001183067.1_MUCL30388 | cds-NP_014170.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:210803-211867:- | gene-YNL229C_MUCL39482 | rna-NM_001183067.1_MUCL39482 | cds-NP_014170.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:213058-214122:- | gene-YNL229C_MUCL42920 | rna-NM_001183067.1_MUCL42920 | cds-NP_014170.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:219106-220170:- | gene-YNL229C_NCIM3186 | rna-NM_001183067.1_NCIM3186 | cds-NP_014170.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:212896-213960:- | gene-YNL229C_NCYC1407 | rna-NM_001183067.1_NCYC1407 | cds-NP_014170.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:209796-210860:- | gene-YNL229C_PE2H3 | rna-NM_001183067.1_PE2H3 | cds-NP_014170.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:209184-210248:- | gene-YNL229C_PE2H4 | rna-NM_001183067.1_PE2H4 | cds-NP_014170.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:219137-220201:- | gene-YNL229C_S288C | rna-NM_001183067.1_S288C | cds-NP_014170.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:32102-33166:+ | gene-YNL229C_SA1 | rna-NM_001183067.1_SA1 | cds-NP_014170.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:206164-207228:- | gene-YNL229C_ThermosaccDry | rna-NM_001183067.1_ThermosaccDry | cds-NP_014170.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:225152-226216:- | gene-YNL229C_VR1 | rna-NM_001183067.1_VR1 | cds-NP_014170.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:116482-117546:- | gene-YNL229C_ZTW1 | rna-NM_001183067.1_ZTW1 | cds-NP_014170.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:216531-217610:- | gene-YNL229C_Sparadoxus | rna-NM_001183067.1_Sparadoxus | cds-NP_014170.1_Sparadoxus | 91.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |