Gene name: URA8
Reference locus (S288C): YJR103W
Gene biotype: protein_coding
Description: Minor CTP synthase isozyme (see also URA7); catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis; capable of forming cytoplasmic filaments termed cytoophidium, especially during conditions of glucose depletion; URA8 has a paralog, URA7, that arose from the whole genome duplication
Top 10 interactors (score): URA7 (0.999); GUA1 (0.978); YNK1 (0.962); IMD2 (0.941); IMD3 (0.937); URA2 (0.935); ADE12 (0.931); RPA135 (0.925); RPA190 (0.916); YND1 (0.908); URA1 (0.874); ASN2 (0.865); LIA1 (0.857); SGT2 (0.851); ADE4 (0.832); IMD4 (0.832); URA10 (0.83); ASN1 (0.829); IMD1 (0.825); GCD7 (0.814)
Homologues (species, bitscore): CTPS1 (Homo sapiens, 664.5); Ctps (Mus musculus, 667.2); ctps1b (Danio rerio, 679.1); ctps1 (Xenopus tropicalis, 659.1); CTPsyn (Drosophila melanogaster, 637.1); ctps-1 (Caenorhabditis elegans, 565.1); emb2742 (Arabidopsis thaliana, 643.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:592258-593994:+ | gene-YJR103W_AKU4011 | rna-NM_001181761.4_AKU4011 | cds-NP_012637.4_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:13600-15336:- | gene-YJR103W_BG1 | rna-NM_001181761.4_BG1 | cds-NP_012637.4_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:607987-609722:+ | gene-YJR103W_Bruggeman | rna-NM_001181761.4_Bruggeman | cds-NP_012637.4_Bruggeman | 99.7 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:611466-613202:+ | gene-YJR103W_CAT1 | rna-NM_001181761.4_CAT1 | cds-NP_012637.4_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:604314-606050:+ | gene-YJR103W_CBS1585 | rna-NM_001181761.4_CBS1585 | cds-NP_012637.4_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:622905-624641:+ | gene-YJR103W_CBS436 | rna-NM_001181761.4_CBS436 | cds-NP_012637.4_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:591461-593197:+ | gene-YJR103W_CBS6412 | rna-NM_001181761.4_CBS6412 | cds-NP_012637.4_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:593722-595458:+ | gene-YJR103W_CBS6413 | rna-NM_001181761.4_CBS6413 | cds-NP_012637.4_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:603072-604808:+ | gene-YJR103W_CENPK1137D | rna-NM_001181761.4_CENPK1137D | cds-NP_012637.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:596676-598412:+ | gene-YJR103W_EthanolRed | rna-NM_001181761.4_EthanolRed | cds-NP_012637.4_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:608142-609878:+ | gene-YJR103W_FaliES1 | rna-NM_001181761.4_FaliES1 | cds-NP_012637.4_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000054.1:79543-81279:- | gene-YJR103W_JAY291 | rna-NM_001181761.4_JAY291 | cds-NP_012637.4_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:606536-608271:+ | gene-YJR103W_MUCL30387 | rna-NM_001181761.4_MUCL30387 | cds-NP_012637.4_MUCL30387 | 99.7 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:604505-606241:+ | gene-YJR103W_MUCL30388 | rna-NM_001181761.4_MUCL30388 | cds-NP_012637.4_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:597782-599518:+ | gene-YJR103W_MUCL39482 | rna-NM_001181761.4_MUCL39482 | cds-NP_012637.4_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:602033-603769:+ | gene-YJR103W_MUCL42920 | rna-NM_001181761.4_MUCL42920 | cds-NP_012637.4_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:620733-622469:+ | gene-YJR103W_NCIM3186 | rna-NM_001181761.4_NCIM3186 | cds-NP_012637.4_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:595340-597076:+ | gene-YJR103W_NCYC1407 | rna-NM_001181761.4_NCYC1407 | cds-NP_012637.4_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:613237-614973:+ | gene-YJR103W_PE2H3 | rna-NM_001181761.4_PE2H3 | cds-NP_012637.4_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:606926-608662:+ | gene-YJR103W_PE2H4 | rna-NM_001181761.4_PE2H4 | cds-NP_012637.4_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:620754-622490:+ | gene-YJR103W_S288C | rna-NM_001181761.4_S288C | cds-NP_012637.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000038.1:79311-81047:+ | gene-YJR103W_SA1 | rna-NM_001181761.4_SA1 | cds-NP_012637.4_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:602076-603812:+ | gene-YJR103W_ThermosaccDry | rna-NM_001181761.4_ThermosaccDry | cds-NP_012637.4_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:604181-605917:+ | gene-YJR103W_VR1 | rna-NM_001181761.4_VR1 | cds-NP_012637.4_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:581441-583177:+ | gene-YJR103W_ZTW1 | rna-NM_001181761.4_ZTW1 | cds-NP_012637.4_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:615257-616993:+ | gene-YJR103W_Sparadoxus | rna-NM_001181761.4_Sparadoxus | cds-NP_012637.4_Sparadoxus | 91.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |