URA7 (YBL039C)


Gene profile

Gene name: URA7
Reference locus (S288C): YBL039C
Gene biotype: protein_coding

Description: Major CTP synthase isozyme (see also URA8); catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis; capable of forming cytoplasmic filaments termed cytoophidium, especially during conditions of glucose depletion; URA7 has a paralog, URA8, that arose from the whole genome duplication

Top 10 interactors (score): URA8 (0.999); GUA1 (0.998); RPA135 (0.993); ARX1 (0.981); LIA1 (0.978); RRB1 (0.965); ERB1 (0.964); YNK1 (0.963); AAH1 (0.961); BRX1 (0.961); NOP56 (0.955); NOG1 (0.953); MRT4 (0.945); PWP1 (0.945); YTM1 (0.944); ASN2 (0.944); CIC1 (0.936); HAS1 (0.936); NOP1 (0.936); RPA190 (0.934)

Homologues (species, bitscore): CTPS1 (Homo sapiens, 684.1); Ctps (Mus musculus, 688.7); ctps1a (Danio rerio, 688.7); ctps1 (Xenopus tropicalis, 679.9); CTPsyn (Drosophila melanogaster, 634.0); ctps-1 (Caenorhabditis elegans, 550.1); emb2742 (Arabidopsis thaliana, 665.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:137604-139343:- gene-YBL039C_AKU4011 rna-NM_001178279.1_AKU4011 cds-NP_009514.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:128430-130169:- gene-YBL039C_BG1 rna-NM_001178279.1_BG1 cds-NP_009514.1_BG1 99.4 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:138199-139938:- gene-YBL039C_Bruggeman rna-NM_001178279.1_Bruggeman cds-NP_009514.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:140827-142566:- gene-YBL039C_CAT1 rna-NM_001178279.1_CAT1 cds-NP_009514.1_CAT1 99.4 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:130144-131883:- gene-YBL039C_CBS1585 rna-NM_001178279.1_CBS1585 cds-NP_009514.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:138661-140400:- gene-YBL039C_CBS436 rna-NM_001178279.1_CBS436 cds-NP_009514.1_CBS436 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:228898-230637:- gene-YBL039C_CBS6412 rna-NM_001178279.1_CBS6412 cds-NP_009514.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:135715-137454:- gene-YBL039C_CBS6413 rna-NM_001178279.1_CBS6413 cds-NP_009514.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:137746-139485:- gene-YBL039C_CENPK1137D rna-NM_001178279.1_CENPK1137D cds-NP_009514.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:151562-153301:- gene-YBL039C_EthanolRed rna-NM_001178279.1_EthanolRed cds-NP_009514.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:152412-154151:- gene-YBL039C_FaliES1 rna-NM_001178279.1_FaliES1 cds-NP_009514.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000072.1:55054-56793:- gene-YBL039C_JAY291 rna-NM_001178279.1_JAY291 cds-NP_009514.1_JAY291 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:137576-139315:- gene-YBL039C_MUCL30387 rna-NM_001178279.1_MUCL30387 cds-NP_009514.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:138850-140589:- gene-YBL039C_MUCL30388 rna-NM_001178279.1_MUCL30388 cds-NP_009514.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:130319-132058:- gene-YBL039C_MUCL39482 rna-NM_001178279.1_MUCL39482 cds-NP_009514.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:137161-138900:- gene-YBL039C_MUCL42920 rna-NM_001178279.1_MUCL42920 cds-NP_009514.1_MUCL42920 99.5 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:143786-145525:- gene-YBL039C_NCIM3186 rna-NM_001178279.1_NCIM3186 cds-NP_009514.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:131456-133195:- gene-YBL039C_NCYC1407 rna-NM_001178279.1_NCYC1407 cds-NP_009514.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:137731-139470:- gene-YBL039C_PE2H3 rna-NM_001178279.1_PE2H3 cds-NP_009514.1_PE2H3 99.5 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:135375-137114:- gene-YBL039C_PE2H4 rna-NM_001178279.1_PE2H4 cds-NP_009514.1_PE2H4 99.5 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:143989-145728:- gene-YBL039C_S288C rna-NM_001178279.1_S288C cds-NP_009514.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000051.1:28582-30321:- gene-YBL039C_SA1 rna-NM_001178279.1_SA1 cds-NP_009514.1_SA1 99.4 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:152376-154115:- gene-YBL039C_ThermosaccDry rna-NM_001178279.1_ThermosaccDry cds-NP_009514.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:134560-136299:- gene-YBL039C_VR1 rna-NM_001178279.1_VR1 cds-NP_009514.1_VR1 99.5 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:129078-130817:- gene-YBL039C_ZTW1 rna-NM_001178279.1_ZTW1 cds-NP_009514.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:163958-165697:- gene-YBL039C_Sparadoxus rna-NM_001178279.1_Sparadoxus cds-NP_009514.1_Sparadoxus 91.7 100.0 Verified 1 1 1 False True False False False

Additional files