URA6 (YKL024C)


Gene profile

Gene name: URA6
Reference locus (S288C): YKL024C
Gene biotype: protein_coding

Description: Uridylate kinase; catalyzes the seventh enzymatic step in the de novo biosynthesis of pyrimidines, converting uridine monophosphate (UMP) into uridine-5'-diphosphate (UDP); Belongs to the adenylate kinase family. UMP-CMP kinase subfamily

Top 10 interactors (score): URK1 (0.997); YNK1 (0.991); CDC8 (0.977); URA3 (0.965); FUR1 (0.957); DAS2 (0.955); DCD1 (0.948); RNR3 (0.92); URA1 (0.92); RNR1 (0.92); URA2 (0.916); URA4 (0.912); YND1 (0.907); RNR2 (0.906); URA5 (0.903); RNR4 (0.902); CDD1 (0.893); PCM1 (0.866); QRI1 (0.841); DUG1 (0.838)

Homologues (species, bitscore): CMPK1 (Homo sapiens, 191.4); Cmpk1 (Mus musculus, 192.2); cmpk (Danio rerio, 203.4); cmpk1 (Xenopus tropicalis, 203.0); Dak1 (Drosophila melanogaster, 188.3); C29F7.3 (Caenorhabditis elegans, 183.3); PYR6 (Arabidopsis thaliana, 199.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:378544-379158:- gene-YKL024C_AKU4011 rna-NM_001179590.3_AKU4011 cds-NP_012901.3_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:264746-265360:+ gene-YKL024C_BG1 rna-NM_001179590.3_BG1 cds-NP_012901.3_BG1 99.3 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:400239-400853:- gene-YKL024C_Bruggeman rna-NM_001179590.3_Bruggeman cds-NP_012901.3_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:395354-395968:- gene-YKL024C_CAT1 rna-NM_001179590.3_CAT1 cds-NP_012901.3_CAT1 99.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:391263-391877:- gene-YKL024C_CBS1585 rna-NM_001179590.3_CBS1585 cds-NP_012901.3_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:390113-390727:- gene-YKL024C_CBS436 rna-NM_001179590.3_CBS436 cds-NP_012901.3_CBS436 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:375419-376033:- gene-YKL024C_CBS6412 rna-NM_001179590.3_CBS6412 cds-NP_012901.3_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:391118-391732:- gene-YKL024C_CBS6413 rna-NM_001179590.3_CBS6413 cds-NP_012901.3_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:392203-392817:- gene-YKL024C_CENPK1137D rna-NM_001179590.3_CENPK1137D cds-NP_012901.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:389040-389654:- gene-YKL024C_EthanolRed rna-NM_001179590.3_EthanolRed cds-NP_012901.3_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:391130-391744:- gene-YKL024C_FaliES1 rna-NM_001179590.3_FaliES1 cds-NP_012901.3_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000142.1:39305-39919:+ gene-YKL024C_JAY291 rna-NM_001179590.3_JAY291 cds-NP_012901.3_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:399554-400168:- gene-YKL024C_MUCL30387 rna-NM_001179590.3_MUCL30387 cds-NP_012901.3_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:395163-395777:- gene-YKL024C_MUCL30388 rna-NM_001179590.3_MUCL30388 cds-NP_012901.3_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:390580-391194:- gene-YKL024C_MUCL39482 rna-NM_001179590.3_MUCL39482 cds-NP_012901.3_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:396407-397021:- gene-YKL024C_MUCL42920 rna-NM_001179590.3_MUCL42920 cds-NP_012901.3_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:392515-393129:- gene-YKL024C_NCIM3186 rna-NM_001179590.3_NCIM3186 cds-NP_012901.3_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:390772-391386:- gene-YKL024C_NCYC1407 rna-NM_001179590.3_NCYC1407 cds-NP_012901.3_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:415463-416077:- gene-YKL024C_PE2H3 rna-NM_001179590.3_PE2H3 cds-NP_012901.3_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:400207-400821:- gene-YKL024C_PE2H4 rna-NM_001179590.3_PE2H4 cds-NP_012901.3_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:392526-393140:- gene-YKL024C_S288C rna-NM_001179590.3_S288C cds-NP_012901.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000027.1:70805-71419:- gene-YKL024C_SA1 rna-NM_001179590.3_SA1 cds-NP_012901.3_SA1 99.0 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:391229-391843:- gene-YKL024C_ThermosaccDry rna-NM_001179590.3_ThermosaccDry cds-NP_012901.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:390486-391100:- gene-YKL024C_VR1 rna-NM_001179590.3_VR1 cds-NP_012901.3_VR1 98.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:389257-389871:- gene-YKL024C_ZTW1 rna-NM_001179590.3_ZTW1 cds-NP_012901.3_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:414241-414855:- gene-YKL024C_Sparadoxus rna-NM_001179590.3_Sparadoxus cds-NP_012901.3_Sparadoxus 88.7 100.0 Verified 1 1 1 False True False False False

Additional files