Gene name: URA5
Reference locus (S288C): YML106W
Gene biotype: protein_coding
Description: Major orotate phosphoribosyltransferase (OPRTase) isozyme; catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; URA5 has a paralog, URA10, that arose from the whole genome duplication; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily
Top 10 interactors (score): URA1 (0.999); URA3 (0.994); PPR1 (0.988); URA2 (0.988); URA4 (0.986); URA10 (0.975); LAC1 (0.91); URA6 (0.903); GUA1 (0.899); AAT2 (0.881); PML39 (0.872); SOD1 (0.872); URA7 (0.872); SIR3 (0.866); GOT1 (0.863); CST6 (0.856); ZAP1 (0.854); OPI1 (0.85); URA8 (0.809); URK1 (0.788)
Homologues (species, bitscore): UMPS (Homo sapiens, 90.1); Umps (Mus musculus, 84.7); umps (Danio rerio, 90.1); r-l (Drosophila melanogaster, 59.7); R12E2.11 (Caenorhabditis elegans, 86.7); AT3G54470 (Arabidopsis thaliana, 70.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:50496-51176:+ | gene-YML106W_AKU4011 | rna-NM_001182468.1_AKU4011 | cds-NP_013601.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:424948-425628:- | gene-YML106W_BG1 | rna-NM_001182468.1_BG1 | cds-NP_013601.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:56755-57435:+ | gene-YML106W_Bruggeman | rna-NM_001182468.1_Bruggeman | cds-NP_013601.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:58309-58989:+ | gene-YML106W_CAT1 | rna-NM_001182468.1_CAT1 | cds-NP_013601.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:50497-51177:+ | gene-YML106W_CBS1585 | rna-NM_001182468.1_CBS1585 | cds-NP_013601.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:56493-57173:+ | gene-YML106W_CBS436 | rna-NM_001182468.1_CBS436 | cds-NP_013601.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:51260-51940:+ | gene-YML106W_CBS6412 | rna-NM_001182468.1_CBS6412 | cds-NP_013601.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:49724-50404:+ | gene-YML106W_CBS6413 | rna-NM_001182468.1_CBS6413 | cds-NP_013601.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:51371-52051:+ | gene-YML106W_CENPK1137D | rna-NM_001182468.1_CENPK1137D | cds-NP_013601.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:51007-51687:+ | gene-YML106W_EthanolRed | rna-NM_001182468.1_EthanolRed | cds-NP_013601.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:51283-51963:+ | gene-YML106W_FaliES1 | rna-NM_001182468.1_FaliES1 | cds-NP_013601.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000345.1:38218-38898:- | gene-YML106W_JAY291 | rna-NM_001182468.1_JAY291 | cds-NP_013601.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:55206-55886:+ | gene-YML106W_MUCL30387 | rna-NM_001182468.1_MUCL30387 | cds-NP_013601.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:58425-59105:+ | gene-YML106W_MUCL30388 | rna-NM_001182468.1_MUCL30388 | cds-NP_013601.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:50512-51192:+ | gene-YML106W_MUCL39482 | rna-NM_001182468.1_MUCL39482 | cds-NP_013601.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:54669-55349:+ | gene-YML106W_MUCL42920 | rna-NM_001182468.1_MUCL42920 | cds-NP_013601.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:56727-57407:+ | gene-YML106W_NCIM3186 | rna-NM_001182468.1_NCIM3186 | cds-NP_013601.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:51306-51986:+ | gene-YML106W_NCYC1407 | rna-NM_001182468.1_NCYC1407 | cds-NP_013601.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:56744-57424:+ | gene-YML106W_PE2H3 | rna-NM_001182468.1_PE2H3 | cds-NP_013601.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:56682-57362:+ | gene-YML106W_PE2H4 | rna-NM_001182468.1_PE2H4 | cds-NP_013601.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:56773-57453:+ | gene-YML106W_S288C | rna-NM_001182468.1_S288C | cds-NP_013601.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000054.1:48758-49438:+ | gene-YML106W_SA1 | rna-NM_001182468.1_SA1 | cds-NP_013601.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:50581-51261:+ | gene-YML106W_ThermosaccDry | rna-NM_001182468.1_ThermosaccDry | cds-NP_013601.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:54963-55643:+ | gene-YML106W_VR1 | rna-NM_001182468.1_VR1 | cds-NP_013601.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:30066-30746:+ | gene-YML106W_ZTW1 | rna-NM_001182468.1_ZTW1 | cds-NP_013601.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:61515-62195:+ | gene-YML106W_Sparadoxus | rna-NM_001182468.1_Sparadoxus | cds-NP_013601.1_Sparadoxus | 93.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |