URA4 (YLR420W)


Gene profile

Gene name: URA4
Reference locus (S288C): YLR420W
Gene biotype: protein_coding

Description: Dihydroorotase; catalyzes the third enzymatic step in the de novo biosynthesis of pyrimidines, converting carbamoyl-L-aspartate into dihydroorotate

Top 10 interactors (score): URA1 (0.999); URA2 (0.997); PPR1 (0.994); URA5 (0.986); URA3 (0.963); ADE6 (0.913); URA6 (0.912); YNK1 (0.908); URA10 (0.898); SIR3 (0.889); AAT2 (0.879); MON2 (0.872); PML39 (0.872); CST6 (0.872); TFC7 (0.868); NMT1 (0.823); LCD1 (0.809); LYP1 (0.787); LEU1 (0.779); ESA1 (0.754)

Homologues (species, bitscore): PYR4 (Arabidopsis thaliana, 178.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:907334-908428:+ gene-YLR420W_AKU4011 rna-NM_001182308.1_AKU4011 cds-NP_013524.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000048.1:139499-140593:+ gene-YLR420W_BG1 rna-NM_001182308.1_BG1 cds-NP_013524.1_BG1 99.0 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:945637-946731:+ gene-YLR420W_Bruggeman rna-NM_001182308.1_Bruggeman cds-NP_013524.1_Bruggeman 99.1 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:941184-942278:+ gene-YLR420W_CAT1 rna-NM_001182308.1_CAT1 cds-NP_013524.1_CAT1 99.0 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:942931-944025:+ gene-YLR420W_CBS1585 rna-NM_001182308.1_CBS1585 cds-NP_013524.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:926588-927682:+ gene-YLR420W_CBS436 rna-NM_001182308.1_CBS436 cds-NP_013524.1_CBS436 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:978971-980065:+ gene-YLR420W_CBS6412 rna-NM_001182308.1_CBS6412 cds-NP_013524.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:943223-944317:+ gene-YLR420W_CBS6413 rna-NM_001182308.1_CBS6413 cds-NP_013524.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:942985-944079:+ gene-YLR420W_CENPK1137D rna-NM_001182308.1_CENPK1137D cds-NP_013524.1_CENPK1137D 99.4 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:900214-901308:+ gene-YLR420W_EthanolRed rna-NM_001182308.1_EthanolRed cds-NP_013524.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:929695-930789:+ gene-YLR420W_FaliES1 rna-NM_001182308.1_FaliES1 cds-NP_013524.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000434.1:82328-83422:+ gene-YLR420W_JAY291 rna-NM_001182308.1_JAY291 cds-NP_013524.1_JAY291 99.0 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:944500-945594:+ gene-YLR420W_MUCL30387 rna-NM_001182308.1_MUCL30387 cds-NP_013524.1_MUCL30387 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:950603-951697:+ gene-YLR420W_MUCL30388 rna-NM_001182308.1_MUCL30388 cds-NP_013524.1_MUCL30388 99.1 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:944151-945245:+ gene-YLR420W_MUCL39482 rna-NM_001182308.1_MUCL39482 cds-NP_013524.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:938808-939902:+ gene-YLR420W_MUCL42920 rna-NM_001182308.1_MUCL42920 cds-NP_013524.1_MUCL42920 99.1 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:963759-964853:+ gene-YLR420W_NCIM3186 rna-NM_001182308.1_NCIM3186 cds-NP_013524.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:953330-954424:+ gene-YLR420W_NCYC1407 rna-NM_001182308.1_NCYC1407 cds-NP_013524.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:939709-940803:+ gene-YLR420W_PE2H3 rna-NM_001182308.1_PE2H3 cds-NP_013524.1_PE2H3 99.0 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:939453-940547:+ gene-YLR420W_PE2H4 rna-NM_001182308.1_PE2H4 cds-NP_013524.1_PE2H4 99.0 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:963785-964879:+ gene-YLR420W_S288C rna-NM_001182308.1_S288C cds-NP_013524.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000007.1:89794-90888:- gene-YLR420W_SA1 rna-NM_001182308.1_SA1 cds-NP_013524.1_SA1 98.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:932774-933868:+ gene-YLR420W_ThermosaccDry rna-NM_001182308.1_ThermosaccDry cds-NP_013524.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:945151-946245:+ gene-YLR420W_VR1 rna-NM_001182308.1_VR1 cds-NP_013524.1_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000025.1:268987-270081:+ gene-YLR420W_ZTW1 rna-NM_001182308.1_ZTW1 cds-NP_013524.1_ZTW1 99.9 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:918185-919279:+ gene-YLR420W_Sparadoxus rna-NM_001182308.1_Sparadoxus cds-NP_013524.1_Sparadoxus 90.8 100.0 Verified 1 1 1 False True False False False

Additional files