Gene name: URA3
Reference locus (S288C): YEL021W
Gene biotype: protein_coding
Description: Orotidine-5'-phosphate (OMP) decarboxylase; catalyzes the sixth enzymatic step in the de novo biosynthesis of pyrimidines, converting OMP into uridine monophosphate (UMP); converts 5-FOA into 5-fluorouracil, a toxic compound
Top 10 interactors (score): URA5 (0.994); ADE2 (0.994); URK1 (0.993); FUR1 (0.991); LEU2 (0.982); ADE1 (0.978); URA10 (0.977); URA1 (0.975); HIS3 (0.971); URA2 (0.97); TRP1 (0.97); PGK1 (0.967); HIS4 (0.965); ARG4 (0.965); URA6 (0.965); URA4 (0.963); GAL1 (0.963); LYS2 (0.96); MET17 (0.957); CAN1 (0.951)
Homologues (species, bitscore): UMPS (Homo sapiens, 250.4); Umps (Mus musculus, 251.9); umps (Danio rerio, 250.0); umps (Xenopus tropicalis, 148.3); r-l (Drosophila melanogaster, 208.0); umps-1 (Caenorhabditis elegans, 179.1); AT3G54470 (Arabidopsis thaliana, 252.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:110201-111004:+ | gene-YEL021W_AKU4011 | rna-NM_001178836.3_AKU4011 | cds-NP_010893.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:314955-315758:- | gene-YEL021W_BG1 | rna-NM_001178836.3_BG1 | cds-NP_010893.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:115603-116406:+ | gene-YEL021W_Bruggeman | rna-NM_001178836.3_Bruggeman | cds-NP_010893.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:112385-113188:+ | gene-YEL021W_CAT1 | rna-NM_001178836.3_CAT1 | cds-NP_010893.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:110142-110945:+ | gene-YEL021W_CBS1585 | rna-NM_001178836.3_CBS1585 | cds-NP_010893.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:111775-112578:+ | gene-YEL021W_CBS436 | rna-NM_001178836.3_CBS436 | cds-NP_010893.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:110421-111224:+ | gene-YEL021W_CBS6412 | rna-NM_001178836.3_CBS6412 | cds-NP_010893.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:115034-115837:+ | gene-YEL021W_CBS6413 | rna-NM_001178836.3_CBS6413 | cds-NP_010893.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:114025-114828:+ | gene-YEL021W_CENPK1137D | rna-NM_001178836.3_CENPK1137D | cds-NP_010893.3_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:110532-111335:+ | gene-YEL021W_EthanolRed | rna-NM_001178836.3_EthanolRed | cds-NP_010893.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:110791-111594:+ | gene-YEL021W_FaliES1 | rna-NM_001178836.3_FaliES1 | cds-NP_010893.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000398.1:29676-30479:+ | gene-YEL021W_JAY291 | rna-NM_001178836.3_JAY291 | cds-NP_010893.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:114456-115259:+ | gene-YEL021W_MUCL30387 | rna-NM_001178836.3_MUCL30387 | cds-NP_010893.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:110427-111230:+ | gene-YEL021W_MUCL30388 | rna-NM_001178836.3_MUCL30388 | cds-NP_010893.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:109511-110314:+ | gene-YEL021W_MUCL39482 | rna-NM_001178836.3_MUCL39482 | cds-NP_010893.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:114141-114944:+ | gene-YEL021W_MUCL42920 | rna-NM_001178836.3_MUCL42920 | cds-NP_010893.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:116166-116969:+ | gene-YEL021W_NCIM3186 | rna-NM_001178836.3_NCIM3186 | cds-NP_010893.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:114611-115414:+ | gene-YEL021W_NCYC1407 | rna-NM_001178836.3_NCYC1407 | cds-NP_010893.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:118643-119446:+ | gene-YEL021W_PE2H3 | rna-NM_001178836.3_PE2H3 | cds-NP_010893.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:114558-115361:+ | gene-YEL021W_PE2H4 | rna-NM_001178836.3_PE2H4 | cds-NP_010893.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:116167-116970:+ | gene-YEL021W_S288C | rna-NM_001178836.3_S288C | cds-NP_010893.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000020.1:126262-127065:- | gene-YEL021W_SA1 | rna-NM_001178836.3_SA1 | cds-NP_010893.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:111196-111999:+ | gene-YEL021W_ThermosaccDry | rna-NM_001178836.3_ThermosaccDry | cds-NP_010893.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:110732-111535:+ | gene-YEL021W_VR1 | rna-NM_001178836.3_VR1 | cds-NP_010893.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:109553-110356:+ | gene-YEL021W_ZTW1 | rna-NM_001178836.3_ZTW1 | cds-NP_010893.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:112784-113587:+ | gene-YEL021W_Sparadoxus | rna-NM_001178836.3_Sparadoxus | cds-NP_010893.3_Sparadoxus | 92.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |