Gene name: URA10
Reference locus (S288C): YMR271C
Gene biotype: protein_coding
Description: Minor orotate phosphoribosyltransferase (OPRTase) isozyme; catalyzes the fifth enzymatic step in the de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; URA10 has a paralog, URA5, that arose from the whole genome duplication; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily
Top 10 interactors (score): URA1 (0.991); URA3 (0.977); URA5 (0.975); PPR1 (0.916); URA4 (0.898); URA2 (0.875); ZAP1 (0.859); OPI1 (0.855); GOT1 (0.849); URA7 (0.848); URA8 (0.83); TRP3 (0.79); CDC21 (0.738); CPA2 (0.733); CPA1 (0.731); GUA1 (0.722); AIM18 (0.715); ADE5,7 (0.692); ARG5,6 (0.688); ADE4 (0.681)
Homologues (species, bitscore): UMPS (Homo sapiens, 72.4); Umps (Mus musculus, 72.0); umps (Danio rerio, 77.0); r-l (Drosophila melanogaster, 56.2); R12E2.11 (Caenorhabditis elegans, 74.3); AT3G54470 (Arabidopsis thaliana, 72.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:846320-847003:- | gene-YMR271C_AKU4011 | rna-NM_001182778.1_AKU4011 | cds-NP_013998.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:107390-108073:+ | gene-YMR271C_BG1 | rna-NM_001182778.1_BG1 | cds-NP_013998.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:791532-792215:- | gene-YMR271C_Bruggeman | rna-NM_001182778.1_Bruggeman | cds-NP_013998.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:794558-795241:- | gene-YMR271C_CAT1 | rna-NM_001182778.1_CAT1 | cds-NP_013998.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:778570-779253:- | gene-YMR271C_CBS1585 | rna-NM_001182778.1_CBS1585 | cds-NP_013998.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:800501-801184:- | gene-YMR271C_CBS436 | rna-NM_001182778.1_CBS436 | cds-NP_013998.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:890125-890808:- | gene-YMR271C_CBS6412 | rna-NM_001182778.1_CBS6412 | cds-NP_013998.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:777672-778355:- | gene-YMR271C_CBS6413 | rna-NM_001182778.1_CBS6413 | cds-NP_013998.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:801273-801956:- | gene-YMR271C_CENPK1137D | rna-NM_001182778.1_CENPK1137D | cds-NP_013998.1_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:839008-839691:- | gene-YMR271C_EthanolRed | rna-NM_001182778.1_EthanolRed | cds-NP_013998.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:785035-785718:- | gene-YMR271C_FaliES1 | rna-NM_001182778.1_FaliES1 | cds-NP_013998.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000141.1:815-1498:+ | gene-YMR271C_JAY291 | rna-NM_001182778.1_JAY291 | cds-NP_013998.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:785358-786041:- | gene-YMR271C_MUCL30387 | rna-NM_001182778.1_MUCL30387 | cds-NP_013998.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:794749-795432:- | gene-YMR271C_MUCL30388 | rna-NM_001182778.1_MUCL30388 | cds-NP_013998.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:779658-780341:- | gene-YMR271C_MUCL39482 | rna-NM_001182778.1_MUCL39482 | cds-NP_013998.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:787706-788389:- | gene-YMR271C_MUCL42920 | rna-NM_001182778.1_MUCL42920 | cds-NP_013998.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:806819-807502:- | gene-YMR271C_NCIM3186 | rna-NM_001182778.1_NCIM3186 | cds-NP_013998.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:779282-779965:- | gene-YMR271C_NCYC1407 | rna-NM_001182778.1_NCYC1407 | cds-NP_013998.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:789274-789957:- | gene-YMR271C_PE2H3 | rna-NM_001182778.1_PE2H3 | cds-NP_013998.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:790346-791029:- | gene-YMR271C_PE2H4 | rna-NM_001182778.1_PE2H4 | cds-NP_013998.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:806865-807548:- | gene-YMR271C_S288C | rna-NM_001182778.1_S288C | cds-NP_013998.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:887-1570:+ | gene-YMR271C_SA1 | rna-NM_001182778.1_SA1 | cds-NP_013998.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:781204-781887:- | gene-YMR271C_ThermosaccDry | rna-NM_001182778.1_ThermosaccDry | cds-NP_013998.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:793814-794497:- | gene-YMR271C_VR1 | rna-NM_001182778.1_VR1 | cds-NP_013998.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:196404-197087:- | gene-YMR271C_ZTW1 | rna-NM_001182778.1_ZTW1 | cds-NP_013998.1_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:799613-800296:- | gene-YMR271C_Sparadoxus | rna-NM_001182778.1_Sparadoxus | cds-NP_013998.1_Sparadoxus | 88.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |