Gene name: URA1
Reference locus (S288C): YKL216W
Gene biotype: protein_coding
Description: Dihydroorotate dehydrogenase (fumarate); Dihydroorotate dehydrogenase; catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid
Top 10 interactors (score): URA4 (0.999); URA5 (0.999); URA2 (0.993); URA10 (0.991); PPR1 (0.98); URA3 (0.975); GUA1 (0.943); RPC40 (0.939); URA6 (0.92); NOP2 (0.917); MRT4 (0.915); NUG1 (0.914); RRB1 (0.907); RRP3 (0.905); BRX1 (0.902); PWP1 (0.902); NOP1 (0.901); UTP4 (0.898); PNO1 (0.896); RRS1 (0.896)
Homologues (species, bitscore): DPYD (Homo sapiens, 68.6); Dhodh (Mus musculus, 72.4); dhodh (Danio rerio, 76.6); dhodh (Xenopus tropicalis, 80.9); Dhod (Drosophila melanogaster, 66.2); dhod-1 (Caenorhabditis elegans, 78.2); PYD1 (Arabidopsis thaliana, 68.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:11032-11976:+ | gene-YKL216W_AKU4011 | rna-NM_001179781.1_AKU4011 | cds-NP_012706.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000083.1:13461-14405:- | gene-YKL216W_BG1 | rna-NM_001179781.1_BG1 | cds-NP_012706.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:29216-30160:+ | gene-YKL216W_Bruggeman | rna-NM_001179781.1_Bruggeman | cds-NP_012706.1_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:23852-24796:+ | gene-YKL216W_CAT1 | rna-NM_001179781.1_CAT1 | cds-NP_012706.1_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:23054-23998:+ | gene-YKL216W_CBS1585 | rna-NM_001179781.1_CBS1585 | cds-NP_012706.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:22760-23704:+ | gene-YKL216W_CBS436 | rna-NM_001179781.1_CBS436 | cds-NP_012706.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:9201-10145:+ | gene-YKL216W_CBS6412 | rna-NM_001179781.1_CBS6412 | cds-NP_012706.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:23679-24623:+ | gene-YKL216W_CBS6413 | rna-NM_001179781.1_CBS6413 | cds-NP_012706.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:25057-26001:+ | gene-YKL216W_CENPK1137D | rna-NM_001179781.1_CENPK1137D | cds-NP_012706.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:23401-24345:+ | gene-YKL216W_EthanolRed | rna-NM_001179781.1_EthanolRed | cds-NP_012706.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:23044-23988:+ | gene-YKL216W_FaliES1 | rna-NM_001179781.1_FaliES1 | cds-NP_012706.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000006.2:22692-23636:+ | gene-YKL216W_JAY291 | rna-NM_001179781.1_JAY291 | cds-NP_012706.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:30771-31715:+ | gene-YKL216W_MUCL30387 | rna-NM_001179781.1_MUCL30387 | cds-NP_012706.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:25098-26042:+ | gene-YKL216W_MUCL30388 | rna-NM_001179781.1_MUCL30388 | cds-NP_012706.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:23106-24050:+ | gene-YKL216W_MUCL39482 | rna-NM_001179781.1_MUCL39482 | cds-NP_012706.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:26903-27847:+ | gene-YKL216W_MUCL42920 | rna-NM_001179781.1_MUCL42920 | cds-NP_012706.1_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:25204-26148:+ | gene-YKL216W_NCIM3186 | rna-NM_001179781.1_NCIM3186 | cds-NP_012706.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:23149-24093:+ | gene-YKL216W_NCYC1407 | rna-NM_001179781.1_NCYC1407 | cds-NP_012706.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:31312-32256:+ | gene-YKL216W_PE2H3 | rna-NM_001179781.1_PE2H3 | cds-NP_012706.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:27516-28460:+ | gene-YKL216W_PE2H4 | rna-NM_001179781.1_PE2H4 | cds-NP_012706.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:25215-26159:+ | gene-YKL216W_S288C | rna-NM_001179781.1_S288C | cds-NP_012706.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000199.1:708-1450:- | gene-YKL216W_SA1 | rna-NM_001179781.1_SA1 | cds-NP_012706.1_SA1 | 77.6 | 78.6 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:23770-24714:+ | gene-YKL216W_ThermosaccDry | rna-NM_001179781.1_ThermosaccDry | cds-NP_012706.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:22941-23885:+ | gene-YKL216W_VR1 | rna-NM_001179781.1_VR1 | cds-NP_012706.1_VR1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:22735-23679:+ | gene-YKL216W_ZTW1 | rna-NM_001179781.1_ZTW1 | cds-NP_012706.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:31466-32410:+ | gene-YKL216W_Sparadoxus | rna-NM_001179781.1_Sparadoxus | cds-NP_012706.1_Sparadoxus | 92.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |