Gene name: UPS3
Reference locus (S288C): YDR185C
Gene biotype: protein_coding
Description: Mitochondrial protein of unknown function; similar to Ups1p and Ups2p which are involved in regulation of mitochondrial cardiolipin and phosphatidylethanolamine levels; null is viable but interacts synthetically with ups1 and ups2 mutations; UPS3 has a paralog, UPS2, that arose from the whole genome duplication
Top 10 interactors (score): MDM35 (0.971); UPS1 (0.795); MGM1 (0.748); PGS1 (0.711); TIM22 (0.701); MDM10 (0.68); MDM12 (0.675); UPS2 (0.654); CRD1 (0.652); MDM34 (0.618); TIM21 (0.61); TIM23 (0.58); PSD2 (0.573); MMM1 (0.572); NAT2 (0.54); PSD1 (0.526); MRPL10 (0.525); CHO2 (0.524); DRS1 (0.509); TIM18 (0.497)
Homologues (species, bitscore): SLMO2 (Homo sapiens, 93.6); Slmo2 (Mus musculus, 89.7); slmo2 (Danio rerio, 93.6); slmo1 (Xenopus tropicalis, 82.0); slmo (Drosophila melanogaster, 100.1); F15D3.6 (Caenorhabditis elegans, 79.7); AT5G13070 (Arabidopsis thaliana, 91.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:800463-801002:- | gene-YDR185C_AKU4011 | rna-NM_001180493.1_AKU4011 | cds-NP_010471.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:324798-325337:+ | gene-YDR185C_BG1 | rna-NM_001180493.1_BG1 | cds-NP_010471.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:832884-833423:- | gene-YDR185C_Bruggeman | rna-NM_001180493.1_Bruggeman | cds-NP_010471.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:820131-820670:- | gene-YDR185C_CAT1 | rna-NM_001180493.1_CAT1 | cds-NP_010471.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:790829-791368:- | gene-YDR185C_CBS1585 | rna-NM_001180493.1_CBS1585 | cds-NP_010471.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:819813-820352:- | gene-YDR185C_CBS436 | rna-NM_001180493.1_CBS436 | cds-NP_010471.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:787634-788173:- | gene-YDR185C_CBS6412 | rna-NM_001180493.1_CBS6412 | cds-NP_010471.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:818177-818716:- | gene-YDR185C_CBS6413 | rna-NM_001180493.1_CBS6413 | cds-NP_010471.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:830768-831307:- | gene-YDR185C_CENPK1137D | rna-NM_001180493.1_CENPK1137D | cds-NP_010471.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:801231-801770:- | gene-YDR185C_EthanolRed | rna-NM_001180493.1_EthanolRed | cds-NP_010471.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:809443-809982:- | gene-YDR185C_FaliES1 | rna-NM_001180493.1_FaliES1 | cds-NP_010471.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000068.1:39380-39919:+ | gene-YDR185C_JAY291 | rna-NM_001180493.1_JAY291 | cds-NP_010471.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:818530-819069:- | gene-YDR185C_MUCL30387 | rna-NM_001180493.1_MUCL30387 | cds-NP_010471.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:806772-807311:- | gene-YDR185C_MUCL30388 | rna-NM_001180493.1_MUCL30388 | cds-NP_010471.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:792276-792815:- | gene-YDR185C_MUCL39482 | rna-NM_001180493.1_MUCL39482 | cds-NP_010471.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:730972-731511:- | gene-YDR185C_MUCL42920 | rna-NM_001180493.1_MUCL42920 | cds-NP_010471.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:831857-832396:- | gene-YDR185C_NCIM3186 | rna-NM_001180493.1_NCIM3186 | cds-NP_010471.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:795410-795949:- | gene-YDR185C_NCYC1407 | rna-NM_001180493.1_NCYC1407 | cds-NP_010471.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:812161-812700:- | gene-YDR185C_PE2H3 | rna-NM_001180493.1_PE2H3 | cds-NP_010471.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:811466-812005:- | gene-YDR185C_PE2H4 | rna-NM_001180493.1_PE2H4 | cds-NP_010471.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:831934-832473:- | gene-YDR185C_S288C | rna-NM_001180493.1_S288C | cds-NP_010471.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:177645-178184:- | gene-YDR185C_SA1 | rna-NM_001180493.1_SA1 | cds-NP_010471.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:807598-808137:- | gene-YDR185C_ThermosaccDry | rna-NM_001180493.1_ThermosaccDry | cds-NP_010471.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:822826-823365:- | gene-YDR185C_VR1 | rna-NM_001180493.1_VR1 | cds-NP_010471.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:70309-70848:- | gene-YDR185C_ZTW1 | rna-NM_001180493.1_ZTW1 | cds-NP_010471.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:812581-813120:- | gene-YDR185C_Sparadoxus | rna-NM_001180493.1_Sparadoxus | cds-NP_010471.1_Sparadoxus | 91.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |