Gene name: UPS2
Reference locus (S288C): YLR168C
Gene biotype: protein_coding
Description: Mitochondrial intermembrane space protein; involved in phospholipid metabolism; forms complex with Mdm35p that transfers phosphatidylserine from outer membrane to inner membrane for phosphatidylethanolamine synthesis; null mutant has defects in mitochondrial morphology; similar to Ups1p, Ups3p and to human PRELI; UPS2 has a paralog, UPS3, that arose from the whole genome duplication; Belongs to the slowmo family
Top 10 interactors (score): MDM35 (0.999); UPS1 (0.921); MDM31 (0.896); CRD1 (0.869); TAM41 (0.845); PHB1 (0.835); PSD2 (0.828); YME1 (0.823); PSD1 (0.813); MDM32 (0.794); PGS1 (0.774); GEP4 (0.762); MGM1 (0.747); MDM10 (0.747); CHO1 (0.715); MIC60 (0.715); CLD1 (0.703); MDM34 (0.698); ATP23 (0.693); PHB2 (0.691)
Homologues (species, bitscore): SLMO2 (Homo sapiens, 107.1); Slmo1 (Mus musculus, 103.2); slmo2 (Danio rerio, 108.6); slmo1 (Xenopus tropicalis, 102.8); slmo (Drosophila melanogaster, 125.2); F15D3.6 (Caenorhabditis elegans, 99.0); AT5G13070 (Arabidopsis thaliana, 93.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:453681-454373:- | gene-YLR168C_AKU4011 | rna-NM_001182055.1_AKU4011 | cds-NP_013269.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000177.1:10909-11601:- | gene-YLR168C_BG1 | rna-NM_001182055.1_BG1 | cds-NP_013269.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:494022-494714:- | gene-YLR168C_Bruggeman | rna-NM_001182055.1_Bruggeman | cds-NP_013269.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:493552-494244:- | gene-YLR168C_CAT1 | rna-NM_001182055.1_CAT1 | cds-NP_013269.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:489178-489870:- | gene-YLR168C_CBS1585 | rna-NM_001182055.1_CBS1585 | cds-NP_013269.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:479318-480010:- | gene-YLR168C_CBS436 | rna-NM_001182055.1_CBS436 | cds-NP_013269.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:457749-458441:- | gene-YLR168C_CBS6412 | rna-NM_001182055.1_CBS6412 | cds-NP_013269.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:489484-490176:- | gene-YLR168C_CBS6413 | rna-NM_001182055.1_CBS6413 | cds-NP_013269.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:484295-484987:- | gene-YLR168C_CENPK1137D | rna-NM_001182055.1_CENPK1137D | cds-NP_013269.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:453202-453894:- | gene-YLR168C_EthanolRed | rna-NM_001182055.1_EthanolRed | cds-NP_013269.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:482129-482821:- | gene-YLR168C_FaliES1 | rna-NM_001182055.1_FaliES1 | cds-NP_013269.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000004.1:9062-9754:- | gene-YLR168C_JAY291 | rna-NM_001182055.1_JAY291 | cds-NP_013269.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:494043-494735:- | gene-YLR168C_MUCL30387 | rna-NM_001182055.1_MUCL30387 | cds-NP_013269.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:498975-499667:- | gene-YLR168C_MUCL30388 | rna-NM_001182055.1_MUCL30388 | cds-NP_013269.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:490175-490867:- | gene-YLR168C_MUCL39482 | rna-NM_001182055.1_MUCL39482 | cds-NP_013269.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:490747-491439:- | gene-YLR168C_MUCL42920 | rna-NM_001182055.1_MUCL42920 | cds-NP_013269.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:499552-500244:- | gene-YLR168C_NCIM3186 | rna-NM_001182055.1_NCIM3186 | cds-NP_013269.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:482599-483291:- | gene-YLR168C_NCYC1407 | rna-NM_001182055.1_NCYC1407 | cds-NP_013269.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:486849-487541:- | gene-YLR168C_PE2H3 | rna-NM_001182055.1_PE2H3 | cds-NP_013269.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:486593-487285:- | gene-YLR168C_PE2H4 | rna-NM_001182055.1_PE2H4 | cds-NP_013269.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:499578-500270:- | gene-YLR168C_S288C | rna-NM_001182055.1_S288C | cds-NP_013269.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000042.1:9120-9812:- | gene-YLR168C_SA1 | rna-NM_001182055.1_SA1 | cds-NP_013269.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:484653-485345:- | gene-YLR168C_ThermosaccDry | rna-NM_001182055.1_ThermosaccDry | cds-NP_013269.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:495962-496654:- | gene-YLR168C_VR1 | rna-NM_001182055.1_VR1 | cds-NP_013269.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:9022-9714:- | gene-YLR168C_ZTW1 | rna-NM_001182055.1_ZTW1 | cds-NP_013269.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:470671-471363:- | gene-YLR168C_Sparadoxus | rna-NM_001182055.1_Sparadoxus | cds-NP_013269.1_Sparadoxus | 92.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |