UPS1 (YLR193C)


Gene profile

Gene name: UPS1
Reference locus (S288C): YLR193C
Gene biotype: protein_coding

Description: Protein UPS1, mitochondrial; Phosphatidic acid transfer protein; plays a role in phospholipid metabolism by transporting phosphatidic acid from the outer to the inner mitochondrial membrane; localizes to the mitochondrial intermembrane space; null mutant has altered cardiolipin and phosphatidic acid levels; ortholog of human PRELI; Belongs to the slowmo family

Top 10 interactors (score): MDM35 (0.999); TAM41 (0.939); UPS2 (0.921); CRD1 (0.906); MDM31 (0.874); PHB1 (0.868); PSD1 (0.86); PGS1 (0.842); GEP4 (0.842); TIM17 (0.838); PTR2 (0.835); MGM1 (0.823); MDM32 (0.811); MDM34 (0.798); UPS3 (0.795); MDM10 (0.771); CLD1 (0.76); FZO1 (0.751); ATP23 (0.738); YME1 (0.734)

Homologues (species, bitscore): PRELID1 (Homo sapiens, 100.1); Prelid1 (Mus musculus, 100.9); prelid1a (Danio rerio, 103.6); prelid1 (Xenopus tropicalis, 105.1); prel (Drosophila melanogaster, 90.1); B0334.4 (Caenorhabditis elegans, 63.9); AT5G13070 (Arabidopsis thaliana, 56.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:494129-494656:- gene-YLR193C_AKU4011 rna-NM_001182080.1_AKU4011 cds-NP_013294.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000177.1:51310-51837:- gene-YLR193C_BG1 rna-NM_001182080.1_BG1 cds-NP_013294.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:534379-534906:- gene-YLR193C_Bruggeman rna-NM_001182080.1_Bruggeman cds-NP_013294.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:533974-534501:- gene-YLR193C_CAT1 rna-NM_001182080.1_CAT1 cds-NP_013294.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:529626-530153:- gene-YLR193C_CBS1585 rna-NM_001182080.1_CBS1585 cds-NP_013294.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:519766-520293:- gene-YLR193C_CBS436 rna-NM_001182080.1_CBS436 cds-NP_013294.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:498183-498710:- gene-YLR193C_CBS6412 rna-NM_001182080.1_CBS6412 cds-NP_013294.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:529918-530445:- gene-YLR193C_CBS6413 rna-NM_001182080.1_CBS6413 cds-NP_013294.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:524656-525183:- gene-YLR193C_CENPK1137D rna-NM_001182080.1_CENPK1137D cds-NP_013294.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:493656-494183:- gene-YLR193C_EthanolRed rna-NM_001182080.1_EthanolRed cds-NP_013294.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:522583-523110:- gene-YLR193C_FaliES1 rna-NM_001182080.1_FaliES1 cds-NP_013294.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000004.1:49483-50010:- gene-YLR193C_JAY291 rna-NM_001182080.1_JAY291 cds-NP_013294.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:534399-534926:- gene-YLR193C_MUCL30387 rna-NM_001182080.1_MUCL30387 cds-NP_013294.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:539332-539859:- gene-YLR193C_MUCL30388 rna-NM_001182080.1_MUCL30388 cds-NP_013294.1_MUCL30388 99.4 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:530607-531134:- gene-YLR193C_MUCL39482 rna-NM_001182080.1_MUCL39482 cds-NP_013294.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:531103-531630:- gene-YLR193C_MUCL42920 rna-NM_001182080.1_MUCL42920 cds-NP_013294.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:539983-540510:- gene-YLR193C_NCIM3186 rna-NM_001182080.1_NCIM3186 cds-NP_013294.1_NCIM3186 99.4 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:523036-523563:- gene-YLR193C_NCYC1407 rna-NM_001182080.1_NCYC1407 cds-NP_013294.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:527272-527799:- gene-YLR193C_PE2H3 rna-NM_001182080.1_PE2H3 cds-NP_013294.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:527016-527543:- gene-YLR193C_PE2H4 rna-NM_001182080.1_PE2H4 cds-NP_013294.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:540009-540536:- gene-YLR193C_S288C rna-NM_001182080.1_S288C cds-NP_013294.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000042.1:49541-50068:- gene-YLR193C_SA1 rna-NM_001182080.1_SA1 cds-NP_013294.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:525086-525613:- gene-YLR193C_ThermosaccDry rna-NM_001182080.1_ThermosaccDry cds-NP_013294.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:536385-536912:- gene-YLR193C_VR1 rna-NM_001182080.1_VR1 cds-NP_013294.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000024.1:49375-49902:- gene-YLR193C_ZTW1 rna-NM_001182080.1_ZTW1 cds-NP_013294.1_ZTW1 99.4 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:511147-511674:- gene-YLR193C_Sparadoxus rna-NM_001182080.1_Sparadoxus cds-NP_013294.1_Sparadoxus 91.2 100.0 Verified 1 1 1 False True False False False

Additional files