UNG1 (YML021C)


Gene profile

Gene name: UNG1
Reference locus (S288C): YML021C
Gene biotype: protein_coding

Description: Uracil-DNA glycosylase; required for repair of uracil in DNA formed by spontaneous cytosine deamination; efficiently excises uracil from single-stranded DNA in vivo; not required for strand-specific mismatch repair; cell-cycle regulated, expressed in late G1; localizes to mitochondria and nucleus

Top 10 interactors (score): DUT1 (0.996); APN1 (0.993); APN2 (0.993); CDC21 (0.986); RAD27 (0.982); RFA2 (0.98); OGG1 (0.975); NTG2 (0.974); MSH6 (0.964); NTG1 (0.955); CDC9 (0.945); POL30 (0.932); POL12 (0.925); RAD14 (0.925); PRI1 (0.917); POL1 (0.909); CDC6 (0.896); REV1 (0.892); MCM5 (0.885); MSH2 (0.883)

Homologues (species, bitscore): UNG (Homo sapiens, 229.2); Ung (Mus musculus, 225.7); unga (Danio rerio, 223.0); ung (Xenopus tropicalis, 236.9); ung-1 (Caenorhabditis elegans, 186.8); UNG (Arabidopsis thaliana, 164.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:279328-280407:- gene-YML021C_AKU4011 rna-NM_001182379.1_AKU4011 cds-NP_013691.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:262468-263547:+ gene-YML021C_BG1 rna-NM_001182379.1_BG1 cds-NP_013691.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:219281-220360:- gene-YML021C_Bruggeman rna-NM_001182379.1_Bruggeman cds-NP_013691.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:221791-222870:- gene-YML021C_CAT1 rna-NM_001182379.1_CAT1 cds-NP_013691.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:212278-213357:- gene-YML021C_CBS1585 rna-NM_001182379.1_CBS1585 cds-NP_013691.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:217811-218890:- gene-YML021C_CBS436 rna-NM_001182379.1_CBS436 cds-NP_013691.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:326015-327094:- gene-YML021C_CBS6412 rna-NM_001182379.1_CBS6412 cds-NP_013691.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:211535-212614:- gene-YML021C_CBS6413 rna-NM_001182379.1_CBS6413 cds-NP_013691.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:224256-225335:- gene-YML021C_CENPK1137D rna-NM_001182379.1_CENPK1137D cds-NP_013691.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:212302-213381:- gene-YML021C_EthanolRed rna-NM_001182379.1_EthanolRed cds-NP_013691.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:215266-216345:- gene-YML021C_FaliES1 rna-NM_001182379.1_FaliES1 cds-NP_013691.1_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000033.1:220572-221651:+ gene-YML021C_JAY291 rna-NM_001182379.1_JAY291 cds-NP_013691.1_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:217011-218090:- gene-YML021C_MUCL30387 rna-NM_001182379.1_MUCL30387 cds-NP_013691.1_MUCL30387 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:221680-222759:- gene-YML021C_MUCL30388 rna-NM_001182379.1_MUCL30388 cds-NP_013691.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:212563-213642:- gene-YML021C_MUCL39482 rna-NM_001182379.1_MUCL39482 cds-NP_013691.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:218116-219195:- gene-YML021C_MUCL42920 rna-NM_001182379.1_MUCL42920 cds-NP_013691.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:229688-230767:- gene-YML021C_NCIM3186 rna-NM_001182379.1_NCIM3186 cds-NP_013691.1_NCIM3186 99.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:212504-213583:- gene-YML021C_NCYC1407 rna-NM_001182379.1_NCYC1407 cds-NP_013691.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:218402-219481:- gene-YML021C_PE2H3 rna-NM_001182379.1_PE2H3 cds-NP_013691.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:224497-225576:- gene-YML021C_PE2H4 rna-NM_001182379.1_PE2H4 cds-NP_013691.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:229734-230813:- gene-YML021C_S288C rna-NM_001182379.1_S288C cds-NP_013691.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000088.1:8040-9119:+ gene-YML021C_SA1 rna-NM_001182379.1_SA1 cds-NP_013691.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:212339-213418:- gene-YML021C_ThermosaccDry rna-NM_001182379.1_ThermosaccDry cds-NP_013691.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:216343-217422:- gene-YML021C_VR1 rna-NM_001182379.1_VR1 cds-NP_013691.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:191393-192472:- gene-YML021C_ZTW1 rna-NM_001182379.1_ZTW1 cds-NP_013691.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:223101-224180:- gene-YML021C_Sparadoxus rna-NM_001182379.1_Sparadoxus cds-NP_013691.1_Sparadoxus 89.4 100.0 Verified 1 1 1 False True False False False

Additional files