Gene name: UME6
Reference locus (S288C): YDR207C
Gene biotype: protein_coding
Description: Transcriptional regulatory protein UME6; Rpd3L histone deacetylase complex subunit; key transcriptional regulator of early meiotic genes; involved in chromatin remodeling and transcriptional repression via DNA looping; binds URS1 upstream regulatory sequence, represses transcription by recruiting conserved histone deacetylase Rpd3p (through co-repressor Sin3p) and chromatin-remodeling factor Isw2p; couples metabolic responses to nutritional cues with initiation and progression of meiosis, forms compl
Top 10 interactors (score): RPD3 (0.999); SIN3 (0.998); IME1 (0.998); RXT3 (0.991); SDS3 (0.986); UME1 (0.985); RXT2 (0.984); PHO23 (0.98); CTI6 (0.977); RIM11 (0.974); RCO1 (0.974); DEP1 (0.963); EAF3 (0.959); SAP30 (0.958); RIM15 (0.952); ASH1 (0.947); HOS2 (0.945); STB1 (0.94); TOS4 (0.936); TOD6 (0.929)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:833549-836059:- | gene-YDR207C_AKU4011 | rna-NM_001180515.1_AKU4011 | cds-NP_010493.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:289731-292241:+ | gene-YDR207C_BG1 | rna-NM_001180515.1_BG1 | cds-NP_010493.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:865956-868466:- | gene-YDR207C_Bruggeman | rna-NM_001180515.1_Bruggeman | cds-NP_010493.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:853224-855734:- | gene-YDR207C_CAT1 | rna-NM_001180515.1_CAT1 | cds-NP_010493.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:823909-826419:- | gene-YDR207C_CBS1585 | rna-NM_001180515.1_CBS1585 | cds-NP_010493.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:852963-855473:- | gene-YDR207C_CBS436 | rna-NM_001180515.1_CBS436 | cds-NP_010493.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:820716-823226:- | gene-YDR207C_CBS6412 | rna-NM_001180515.1_CBS6412 | cds-NP_010493.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:851260-853770:- | gene-YDR207C_CBS6413 | rna-NM_001180515.1_CBS6413 | cds-NP_010493.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:863844-866354:- | gene-YDR207C_CENPK1137D | rna-NM_001180515.1_CENPK1137D | cds-NP_010493.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:834287-836797:- | gene-YDR207C_EthanolRed | rna-NM_001180515.1_EthanolRed | cds-NP_010493.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:842499-845009:- | gene-YDR207C_FaliES1 | rna-NM_001180515.1_FaliES1 | cds-NP_010493.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000068.1:4343-6853:+ | gene-YDR207C_JAY291 | rna-NM_001180515.1_JAY291 | cds-NP_010493.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:851612-854122:- | gene-YDR207C_MUCL30387 | rna-NM_001180515.1_MUCL30387 | cds-NP_010493.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:839861-842371:- | gene-YDR207C_MUCL30388 | rna-NM_001180515.1_MUCL30388 | cds-NP_010493.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:825356-827866:- | gene-YDR207C_MUCL39482 | rna-NM_001180515.1_MUCL39482 | cds-NP_010493.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:764058-766568:- | gene-YDR207C_MUCL42920 | rna-NM_001180515.1_MUCL42920 | cds-NP_010493.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:864935-867445:- | gene-YDR207C_NCIM3186 | rna-NM_001180515.1_NCIM3186 | cds-NP_010493.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:828490-831000:- | gene-YDR207C_NCYC1407 | rna-NM_001180515.1_NCYC1407 | cds-NP_010493.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:845230-847740:- | gene-YDR207C_PE2H3 | rna-NM_001180515.1_PE2H3 | cds-NP_010493.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:844547-847057:- | gene-YDR207C_PE2H4 | rna-NM_001180515.1_PE2H4 | cds-NP_010493.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:865012-867522:- | gene-YDR207C_S288C | rna-NM_001180515.1_S288C | cds-NP_010493.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:210726-213236:- | gene-YDR207C_SA1 | rna-NM_001180515.1_SA1 | cds-NP_010493.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:840654-843164:- | gene-YDR207C_ThermosaccDry | rna-NM_001180515.1_ThermosaccDry | cds-NP_010493.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:855877-858387:- | gene-YDR207C_VR1 | rna-NM_001180515.1_VR1 | cds-NP_010493.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:103379-105888:- | gene-YDR207C_ZTW1 | rna-NM_001180515.1_ZTW1 | cds-NP_010493.1_ZTW1 | 99.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:845589-848108:- | gene-YDR207C_Sparadoxus | rna-NM_001180515.1_Sparadoxus | cds-NP_010493.1_Sparadoxus | 89.9 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |