Gene name: UME1
Reference locus (S288C): YPL139C
Gene biotype: protein_coding
Description: Transcriptional regulatory protein UME1; Component of both the Rpd3S and Rpd3L histone deacetylase complexes; negative regulator of meiosis; required for repression of a subset of meiotic genes during vegetative growth, binding of histone deacetylase Rpd3p required for activity, contains a NEE box and a WD repeat motif; homologous with Wtm1p; UME1 has a paralog, WTM2, that arose from the whole genome duplication
Top 10 interactors (score): RPD3 (0.999); RCO1 (0.998); RXT2 (0.998); SIN3 (0.998); CTI6 (0.997); EAF3 (0.996); RXT3 (0.995); SDS3 (0.995); PHO23 (0.994); SAP30 (0.99); DEP1 (0.99); UME6 (0.985); ASH1 (0.983); TOD6 (0.921); SIF2 (0.92); SET3 (0.916); HOS2 (0.915); STB1 (0.913); DOT6 (0.906); SNT1 (0.906)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:267322-268704:- | gene-YPL139C_AKU4011 | rna-NM_001183953.1_AKU4011 | cds-NP_015186.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:473009-474391:- | gene-YPL139C_BG1 | rna-NM_001183953.1_BG1 | cds-NP_015186.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:293318-294700:- | gene-YPL139C_Bruggeman | rna-NM_001183953.1_Bruggeman | cds-NP_015186.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:289996-291378:- | gene-YPL139C_CAT1 | rna-NM_001183953.1_CAT1 | cds-NP_015186.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:271389-272771:- | gene-YPL139C_CBS1585 | rna-NM_001183953.1_CBS1585 | cds-NP_015186.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:286060-287442:- | gene-YPL139C_CBS436 | rna-NM_001183953.1_CBS436 | cds-NP_015186.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:276064-277446:- | gene-YPL139C_CBS6412 | rna-NM_001183953.1_CBS6412 | cds-NP_015186.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:268028-269410:- | gene-YPL139C_CBS6413 | rna-NM_001183953.1_CBS6413 | cds-NP_015186.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:289571-290953:- | gene-YPL139C_CENPK1137D | rna-NM_001183953.1_CENPK1137D | cds-NP_015186.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:266009-267391:- | gene-YPL139C_EthanolRed | rna-NM_001183953.1_EthanolRed | cds-NP_015186.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:273601-274983:- | gene-YPL139C_FaliES1 | rna-NM_001183953.1_FaliES1 | cds-NP_015186.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000007.1:90862-92244:+ | gene-YPL139C_JAY291 | rna-NM_001183953.1_JAY291 | cds-NP_015186.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:284562-285944:- | gene-YPL139C_MUCL30387 | rna-NM_001183953.1_MUCL30387 | cds-NP_015186.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:282575-283957:- | gene-YPL139C_MUCL30388 | rna-NM_001183953.1_MUCL30388 | cds-NP_015186.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:264718-266100:- | gene-YPL139C_MUCL39482 | rna-NM_001183953.1_MUCL39482 | cds-NP_015186.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:321959-323341:- | gene-YPL139C_MUCL42920 | rna-NM_001183953.1_MUCL42920 | cds-NP_015186.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:289652-291034:- | gene-YPL139C_NCIM3186 | rna-NM_001183953.1_NCIM3186 | cds-NP_015186.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:271178-272560:- | gene-YPL139C_NCYC1407 | rna-NM_001183953.1_NCYC1407 | cds-NP_015186.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:278624-280006:- | gene-YPL139C_PE2H3 | rna-NM_001183953.1_PE2H3 | cds-NP_015186.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:278259-279641:- | gene-YPL139C_PE2H4 | rna-NM_001183953.1_PE2H4 | cds-NP_015186.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:289669-291051:- | gene-YPL139C_S288C | rna-NM_001183953.1_S288C | cds-NP_015186.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000012.1:82632-84014:+ | gene-YPL139C_SA1 | rna-NM_001183953.1_SA1 | cds-NP_015186.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:273399-274781:- | gene-YPL139C_ThermosaccDry | rna-NM_001183953.1_ThermosaccDry | cds-NP_015186.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:288380-289762:- | gene-YPL139C_VR1 | rna-NM_001183953.1_VR1 | cds-NP_015186.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:272729-274111:- | gene-YPL139C_ZTW1 | rna-NM_001183953.1_ZTW1 | cds-NP_015186.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:274414-275799:- | gene-YPL139C_Sparadoxus | rna-NM_001183953.1_Sparadoxus | cds-NP_015186.1_Sparadoxus | 87.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |