Gene name: ULS1
Reference locus (S288C): YOR191W
Gene biotype: protein_coding
Description: ATP-dependent helicase ULS1; Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL); required for maintenance of NHEJ inhibition at telomeres; functions at telomeres to translocate and ubiquitinylate poly-sumoylated Rap1p for proteosomal degradation; plays role in antagonizing silencing during mating-type switching; only known STUbL with a translocase activity; contains RING finger domain; relocalizes from nucleus to cytoplasm upon DNA replication stress
Top 10 interactors (score): SMT3 (0.963); RAD18 (0.951); SGS1 (0.925); SRS2 (0.92); MUS81 (0.916); SLX5 (0.894); SLX8 (0.883); RAD51 (0.877); STU2 (0.876); MPH1 (0.873); UBC4 (0.842); POL30 (0.832); RAD52 (0.831); EBP2 (0.825); UBC13 (0.807); UBC9 (0.794); TOP2 (0.775); SIZ1 (0.773); NFI1 (0.773); MMS2 (0.76)
Homologues (species, bitscore): HLTF (Homo sapiens, 242.3); Hltf (Mus musculus, 237.3); hltf (Danio rerio, 237.7); HLTF (Xenopus tropicalis, 251.1); lds (Drosophila melanogaster, 236.9); F54E12.2 (Caenorhabditis elegans, 258.5); AT3G20010 (Arabidopsis thaliana, 313.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:689802-694661:+ | gene-YOR191W_AKU4011 | rna-NM_001183610.1_AKU4011 | cds-NP_014834.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:91854-96713:+ | gene-YOR191W_BG1 | rna-NM_001183610.1_BG1 | cds-NP_014834.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:673810-678669:+ | gene-YOR191W_Bruggeman | rna-NM_001183610.1_Bruggeman | cds-NP_014834.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:674983-679842:+ | gene-YOR191W_CAT1 | rna-NM_001183610.1_CAT1 | cds-NP_014834.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:672791-677650:+ | gene-YOR191W_CBS1585 | rna-NM_001183610.1_CBS1585 | cds-NP_014834.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:670904-675763:+ | gene-YOR191W_CBS436 | rna-NM_001183610.1_CBS436 | cds-NP_014834.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:669907-674766:+ | gene-YOR191W_CBS6412 | rna-NM_001183610.1_CBS6412 | cds-NP_014834.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:678548-683407:+ | gene-YOR191W_CBS6413 | rna-NM_001183610.1_CBS6413 | cds-NP_014834.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:692225-697121:+ | gene-YOR191W_CENPK1137D | rna-NM_001183610.1_CENPK1137D | cds-NP_014834.1_CENPK1137D | 99.2 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:665771-670630:+ | gene-YOR191W_EthanolRed | rna-NM_001183610.1_EthanolRed | cds-NP_014834.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:670844-675703:+ | gene-YOR191W_FaliES1 | rna-NM_001183610.1_FaliES1 | cds-NP_014834.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000038.1:1832-6691:- | gene-YOR191W_JAY291 | rna-NM_001183610.1_JAY291 | cds-NP_014834.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:678614-683473:+ | gene-YOR191W_MUCL30387 | rna-NM_001183610.1_MUCL30387 | cds-NP_014834.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:686029-690888:+ | gene-YOR191W_MUCL30388 | rna-NM_001183610.1_MUCL30388 | cds-NP_014834.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:680121-684980:+ | gene-YOR191W_MUCL39482 | rna-NM_001183610.1_MUCL39482 | cds-NP_014834.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:689502-694361:+ | gene-YOR191W_MUCL42920 | rna-NM_001183610.1_MUCL42920 | cds-NP_014834.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:692364-697223:+ | gene-YOR191W_NCIM3186 | rna-NM_001183610.1_NCIM3186 | cds-NP_014834.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:680218-685077:+ | gene-YOR191W_NCYC1407 | rna-NM_001183610.1_NCYC1407 | cds-NP_014834.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:679040-683899:+ | gene-YOR191W_PE2H3 | rna-NM_001183610.1_PE2H3 | cds-NP_014834.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:689417-694276:+ | gene-YOR191W_PE2H4 | rna-NM_001183610.1_PE2H4 | cds-NP_014834.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:692475-697334:+ | gene-YOR191W_S288C | rna-NM_001183610.1_S288C | cds-NP_014834.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:109034-113893:+ | gene-YOR191W_SA1 | rna-NM_001183610.1_SA1 | cds-NP_014834.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:670028-674887:+ | gene-YOR191W_ThermosaccDry | rna-NM_001183610.1_ThermosaccDry | cds-NP_014834.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:734067-738926:+ | gene-YOR191W_VR1 | rna-NM_001183610.1_VR1 | cds-NP_014834.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:403430-408289:+ | gene-YOR191W_ZTW1 | rna-NM_001183610.1_ZTW1 | cds-NP_014834.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:675743-680599:+ | gene-YOR191W_Sparadoxus | rna-NM_001183610.1_Sparadoxus | cds-NP_014834.1_Sparadoxus | 86.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |