ULA1 (YPL003W)


Gene profile

Gene name: ULA1
Reference locus (S288C): YPL003W
Gene biotype: protein_coding

Description: NEDD8-activating enzyme E1 regulatory subunit; Protein that activates Rub1p (NEDD8) before neddylation; acts together with Uba3p; may play a role in protein degradation; Belongs to the ubiquitin-activating E1 family. ULA1 subfamily

Top 10 interactors (score): UBA3 (0.999); UBC12 (0.999); RUB1 (0.992); CDC53 (0.97); CUL3 (0.938); HRT1 (0.923); CDC34 (0.921); UBA2 (0.918); SKP1 (0.915); RTT101 (0.9); TFB3 (0.882); AOS1 (0.871); YUH1 (0.846); SMT3 (0.837); RRI1 (0.829); URM1 (0.823); DCN1 (0.792); UBA1 (0.778); CDC4 (0.752); YCR1W (0.75)

Homologues (species, bitscore): NAE1 (Homo sapiens, 144.1); Nae1 (Mus musculus, 148.3); nae1 (Danio rerio, 147.5); nae1 (Xenopus tropicalis, 155.2); APP-BP1 (Drosophila melanogaster, 112.8); ula-1 (Caenorhabditis elegans, 110.5); AXL (Arabidopsis thaliana, 136.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:523480-524868:+ gene-YPL003W_AKU4011 rna-NM_001183817.1_AKU4011 cds-NP_015322.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:372309-373697:- gene-YPL003W_BG1 rna-NM_001183817.1_BG1 cds-NP_015322.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:600419-601807:+ gene-YPL003W_Bruggeman rna-NM_001183817.1_Bruggeman cds-NP_015322.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:643165-644553:+ gene-YPL003W_CAT1 rna-NM_001183817.1_CAT1 cds-NP_015322.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:527657-529045:+ gene-YPL003W_CBS1585 rna-NM_001183817.1_CBS1585 cds-NP_015322.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:541721-543109:+ gene-YPL003W_CBS436 rna-NM_001183817.1_CBS436 cds-NP_015322.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:531406-532794:+ gene-YPL003W_CBS6412 rna-NM_001183817.1_CBS6412 cds-NP_015322.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:524117-525505:+ gene-YPL003W_CBS6413 rna-NM_001183817.1_CBS6413 cds-NP_015322.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:552021-553409:+ gene-YPL003W_CENPK1137D rna-NM_001183817.1_CENPK1137D cds-NP_015322.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:521904-523292:+ gene-YPL003W_EthanolRed rna-NM_001183817.1_EthanolRed cds-NP_015322.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:529734-531122:+ gene-YPL003W_FaliES1 rna-NM_001183817.1_FaliES1 cds-NP_015322.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000341.1:6892-8281:- gene-YPL003W_JAY291 rna-NM_001183817.1_JAY291 cds-NP_015322.1_JAY291 99.9 100.0 Unannotated 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:541374-542762:+ gene-YPL003W_MUCL30387 rna-NM_001183817.1_MUCL30387 cds-NP_015322.1_MUCL30387 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:540476-541864:+ gene-YPL003W_MUCL30388 rna-NM_001183817.1_MUCL30388 cds-NP_015322.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:520897-522285:+ gene-YPL003W_MUCL39482 rna-NM_001183817.1_MUCL39482 cds-NP_015322.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:579990-581378:+ gene-YPL003W_MUCL42920 rna-NM_001183817.1_MUCL42920 cds-NP_015322.1_MUCL42920 99.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:552003-553391:+ gene-YPL003W_NCIM3186 rna-NM_001183817.1_NCIM3186 cds-NP_015322.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:528156-529544:+ gene-YPL003W_NCYC1407 rna-NM_001183817.1_NCYC1407 cds-NP_015322.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:534852-536240:+ gene-YPL003W_PE2H3 rna-NM_001183817.1_PE2H3 cds-NP_015322.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:534467-535855:+ gene-YPL003W_PE2H4 rna-NM_001183817.1_PE2H4 cds-NP_015322.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:552020-553408:+ gene-YPL003W_S288C rna-NM_001183817.1_S288C cds-NP_015322.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000076.1:48761-50149:+ gene-YPL003W_SA1 rna-NM_001183817.1_SA1 cds-NP_015322.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:529533-530921:+ gene-YPL003W_ThermosaccDry rna-NM_001183817.1_ThermosaccDry cds-NP_015322.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:544931-546319:+ gene-YPL003W_VR1 rna-NM_001183817.1_VR1 cds-NP_015322.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:528840-530227:+ gene-YPL003W_ZTW1 rna-NM_001183817.1_ZTW1 cds-NP_015322.1_ZTW1 99.3 99.9 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:528708-530096:+ gene-YPL003W_Sparadoxus rna-NM_001183817.1_Sparadoxus cds-NP_015322.1_Sparadoxus 89.2 99.9 Verified 1 1 1 False True False False False

Additional files