Gene name: UGO1
Reference locus (S288C): YDR470C
Gene biotype: protein_coding
Description: Outer membrane component of the mitochondrial fusion machinery; binds to Fzo1p and Mgm1p to link these two GTPases during mitochondrial fusion; involved in fusion of both the outer and inner membranes; facilitates dimerization of Fzo1p during fusion; import into the outer membrane is mediated by Tom70p and Mim1p; has similarity to carrier proteins but likely not a transporter; similar to human SLC25A46 implicated in optic atroprophy spectrum disorder
Top 10 interactors (score): FZO1 (0.999); MGM1 (0.995); TIM23 (0.974); TOM40 (0.946); FIS1 (0.946); MIC60 (0.94); DNM1 (0.909); TOM20 (0.895); TOM70 (0.862); MMM1 (0.857); PCP1 (0.847); MIM1 (0.83); MDM30 (0.827); MDV1 (0.805); TOM22 (0.804); CAF4 (0.789); MIC10 (0.779); MIC19 (0.75); MIC12 (0.749); OM14 (0.747)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1339627-1341138:- | gene-YDR470C_AKU4011 | rna-NM_001180778.2_AKU4011 | cds-NP_010758.3_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:214732-216240:- | gene-YDR470C_BG1 | rna-NM_001180778.2_BG1 | cds-NP_010758.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1371038-1372546:- | gene-YDR470C_Bruggeman | rna-NM_001180778.2_Bruggeman | cds-NP_010758.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1348182-1349690:- | gene-YDR470C_CAT1 | rna-NM_001180778.2_CAT1 | cds-NP_010758.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1333923-1335434:- | gene-YDR470C_CBS1585 | rna-NM_001180778.2_CBS1585 | cds-NP_010758.3_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1353290-1354798:- | gene-YDR470C_CBS436 | rna-NM_001180778.2_CBS436 | cds-NP_010758.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1329550-1331061:- | gene-YDR470C_CBS6412 | rna-NM_001180778.2_CBS6412 | cds-NP_010758.3_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1352561-1354072:- | gene-YDR470C_CBS6413 | rna-NM_001180778.2_CBS6413 | cds-NP_010758.3_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1398402-1399910:- | gene-YDR470C_CENPK1137D | rna-NM_001180778.2_CENPK1137D | cds-NP_010758.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1342964-1344475:- | gene-YDR470C_EthanolRed | rna-NM_001180778.2_EthanolRed | cds-NP_010758.3_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1346517-1348028:- | gene-YDR470C_FaliES1 | rna-NM_001180778.2_FaliES1 | cds-NP_010758.3_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:44774-46282:- | gene-YDR470C_JAY291 | rna-NM_001180778.2_JAY291 | cds-NP_010758.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1353530-1355038:- | gene-YDR470C_MUCL30387 | rna-NM_001180778.2_MUCL30387 | cds-NP_010758.3_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1335552-1337060:- | gene-YDR470C_MUCL30388 | rna-NM_001180778.2_MUCL30388 | cds-NP_010758.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1325407-1326918:- | gene-YDR470C_MUCL39482 | rna-NM_001180778.2_MUCL39482 | cds-NP_010758.3_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1268206-1269714:- | gene-YDR470C_MUCL42920 | rna-NM_001180778.2_MUCL42920 | cds-NP_010758.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1399629-1401137:- | gene-YDR470C_NCIM3186 | rna-NM_001180778.2_NCIM3186 | cds-NP_010758.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1339180-1340691:- | gene-YDR470C_NCYC1407 | rna-NM_001180778.2_NCYC1407 | cds-NP_010758.3_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1350025-1351533:- | gene-YDR470C_PE2H3 | rna-NM_001180778.2_PE2H3 | cds-NP_010758.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1355598-1357106:- | gene-YDR470C_PE2H4 | rna-NM_001180778.2_PE2H4 | cds-NP_010758.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1399706-1401214:- | gene-YDR470C_S288C | rna-NM_001180778.2_S288C | cds-NP_010758.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:215947-217455:+ | gene-YDR470C_SA1 | rna-NM_001180778.2_SA1 | cds-NP_010758.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1350739-1352250:- | gene-YDR470C_ThermosaccDry | rna-NM_001180778.2_ThermosaccDry | cds-NP_010758.3_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1366468-1367976:- | gene-YDR470C_VR1 | rna-NM_001180778.2_VR1 | cds-NP_010758.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:393412-394923:- | gene-YDR470C_ZTW1 | rna-NM_001180778.2_ZTW1 | cds-NP_010758.3_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1353782-1355293:- | gene-YDR470C_Sparadoxus | rna-NM_001180778.2_Sparadoxus | cds-NP_010758.3_Sparadoxus | 89.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |