Gene name: UFD2
Reference locus (S288C): YDL190C
Gene biotype: protein_coding
Description: E4 ubiquitin-protein ligase UFD2; Ubiquitin chain assembly factor (E4); cooperates with a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), and a ubiquitin protein ligase (E3) to conjugate ubiquitin to substrates; also functions as an E3
Top 10 interactors (score): CDC48 (0.999); RAD23 (0.999); DSK2 (0.999); DOA1 (0.996); UFD4 (0.995); SHE4 (0.995); UFD1 (0.994); NPL4 (0.991); AFG2 (0.984); RPN10 (0.971); HUL5 (0.96); OTU1 (0.96); VMS1 (0.955); UBR1 (0.932); UBC4 (0.92); PNG1 (0.918); SHP1 (0.91); DDI1 (0.898); SSM4 (0.897); LRG1 (0.896)
Homologues (species, bitscore): UBE4B (Homo sapiens, 312.0); Ube4b (Mus musculus, 310.5); ube4b (Danio rerio, 312.4); ube4b (Xenopus tropicalis, 312.4); CG9934 (Drosophila melanogaster, 287.0); ufd-2 (Caenorhabditis elegans, 245.4); AT5G15400 (Arabidopsis thaliana, 290.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:102691-105576:- | gene-YDL190C_AKU4011 | rna-NM_001180250.2_AKU4011 | cds-NP_010091.2_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:443589-446474:+ | gene-YDL190C_BG1 | rna-NM_001180250.2_BG1 | cds-NP_010091.2_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:119053-121938:- | gene-YDL190C_Bruggeman | rna-NM_001180250.2_Bruggeman | cds-NP_010091.2_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | MBWC01000024.1:7850-10735:+ | gene-YDL190C_CAT1 | rna-NM_001180250.2_CAT1 | cds-NP_010091.2_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:101231-104116:- | gene-YDL190C_CBS1585 | rna-NM_001180250.2_CBS1585 | cds-NP_010091.2_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:118201-121086:- | gene-YDL190C_CBS436 | rna-NM_001180250.2_CBS436 | cds-NP_010091.2_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:101157-104042:- | gene-YDL190C_CBS6412 | rna-NM_001180250.2_CBS6412 | cds-NP_010091.2_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:119201-122086:- | gene-YDL190C_CBS6413 | rna-NM_001180250.2_CBS6413 | cds-NP_010091.2_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:117378-120263:- | gene-YDL190C_CENPK1137D | rna-NM_001180250.2_CENPK1137D | cds-NP_010091.2_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:114841-117726:- | gene-YDL190C_EthanolRed | rna-NM_001180250.2_EthanolRed | cds-NP_010091.2_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:119948-122833:- | gene-YDL190C_FaliES1 | rna-NM_001180250.2_FaliES1 | cds-NP_010091.2_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000403.1:234-3119:- | gene-YDL190C_JAY291 | rna-NM_001180250.2_JAY291 | cds-NP_010091.2_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:117321-120206:- | gene-YDL190C_MUCL30387 | rna-NM_001180250.2_MUCL30387 | cds-NP_010091.2_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:107134-110019:- | gene-YDL190C_MUCL30388 | rna-NM_001180250.2_MUCL30388 | cds-NP_010091.2_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:102387-105272:- | gene-YDL190C_MUCL39482 | rna-NM_001180250.2_MUCL39482 | cds-NP_010091.2_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:118462-121347:- | gene-YDL190C_MUCL42920 | rna-NM_001180250.2_MUCL42920 | cds-NP_010091.2_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:118630-121515:- | gene-YDL190C_NCIM3186 | rna-NM_001180250.2_NCIM3186 | cds-NP_010091.2_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:102032-104917:- | gene-YDL190C_NCYC1407 | rna-NM_001180250.2_NCYC1407 | cds-NP_010091.2_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:109595-112480:- | gene-YDL190C_PE2H3 | rna-NM_001180250.2_PE2H3 | cds-NP_010091.2_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:109605-112490:- | gene-YDL190C_PE2H4 | rna-NM_001180250.2_PE2H4 | cds-NP_010091.2_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:118707-121592:- | gene-YDL190C_S288C | rna-NM_001180250.2_S288C | cds-NP_010091.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000090.1:33199-36084:- | gene-YDL190C_SA1 | rna-NM_001180250.2_SA1 | cds-NP_010091.2_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:119707-122592:- | gene-YDL190C_ThermosaccDry | rna-NM_001180250.2_ThermosaccDry | cds-NP_010091.2_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:120146-123031:- | gene-YDL190C_VR1 | rna-NM_001180250.2_VR1 | cds-NP_010091.2_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:117881-120766:- | gene-YDL190C_ZTW1 | rna-NM_001180250.2_ZTW1 | cds-NP_010091.2_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:121321-124206:- | gene-YDL190C_Sparadoxus | rna-NM_001180250.2_Sparadoxus | cds-NP_010091.2_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |