UCC1 (YLR224W)


Gene profile

Gene name: UCC1
Reference locus (S288C): YLR224W
Gene biotype: protein_coding

Description: F-box protein and component of SCF ubiquitin ligase complexes; involved in ubiquitin-dependent protein catabolism; readily monoubiquitinated in vitro by SCF-Ubc4 complexes; SCF-Ucc1 regulates level of Cit2 citrate synthase protein to maintain citrate homeostasis, acts as metabolic switch for glyoxylate cycle; UCC1 transcription is downregulated in cells grown on C2-compounds

Top 10 interactors (score): HRT3 (0.895); YDR306C (0.775); YLR352W (0.76); SKP1 (0.707); ROY1 (0.697); COS111 (0.695); SAF1 (0.692); ELA1 (0.617); GET2 (0.586); HRT1 (0.577); SEC28 (0.573); CDC4 (0.573); YKL118W (0.571); YBL094C (0.566); SNT2 (0.566); GET1 (0.539); SSL1 (0.525); STE5 (0.497); DIA2 (0.497); YDR157W (0.497)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:540610-541719:+ gene-YLR224W_AKU4011 rna-NM_001182111.1_AKU4011 cds-NP_013325.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000082.1:546-1655:+ gene-YLR224W_BG1 rna-NM_001182111.1_BG1 cds-NP_013325.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:580832-581941:+ gene-YLR224W_Bruggeman rna-NM_001182111.1_Bruggeman cds-NP_013325.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:580481-581590:+ gene-YLR224W_CAT1 rna-NM_001182111.1_CAT1 cds-NP_013325.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:576104-577213:+ gene-YLR224W_CBS1585 rna-NM_001182111.1_CBS1585 cds-NP_013325.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:566299-567408:+ gene-YLR224W_CBS436 rna-NM_001182111.1_CBS436 cds-NP_013325.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:544665-545774:+ gene-YLR224W_CBS6412 rna-NM_001182111.1_CBS6412 cds-NP_013325.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:576399-577508:+ gene-YLR224W_CBS6413 rna-NM_001182111.1_CBS6413 cds-NP_013325.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:571180-572289:+ gene-YLR224W_CENPK1137D rna-NM_001182111.1_CENPK1137D cds-NP_013325.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:540124-541233:+ gene-YLR224W_EthanolRed rna-NM_001182111.1_EthanolRed cds-NP_013325.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:569049-570158:+ gene-YLR224W_FaliES1 rna-NM_001182111.1_FaliES1 cds-NP_013325.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000004.1:95970-97079:+ gene-YLR224W_JAY291 rna-NM_001182111.1_JAY291 cds-NP_013325.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:581692-582801:+ gene-YLR224W_MUCL30387 rna-NM_001182111.1_MUCL30387 cds-NP_013325.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:585812-586921:+ gene-YLR224W_MUCL30388 rna-NM_001182111.1_MUCL30388 cds-NP_013325.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:577085-578194:+ gene-YLR224W_MUCL39482 rna-NM_001182111.1_MUCL39482 cds-NP_013325.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:577582-578691:+ gene-YLR224W_MUCL42920 rna-NM_001182111.1_MUCL42920 cds-NP_013325.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:586438-587547:+ gene-YLR224W_NCIM3186 rna-NM_001182111.1_NCIM3186 cds-NP_013325.1_NCIM3186 99.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:569503-570612:+ gene-YLR224W_NCYC1407 rna-NM_001182111.1_NCYC1407 cds-NP_013325.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:573773-574882:+ gene-YLR224W_PE2H3 rna-NM_001182111.1_PE2H3 cds-NP_013325.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:573517-574626:+ gene-YLR224W_PE2H4 rna-NM_001182111.1_PE2H4 cds-NP_013325.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:586464-587573:+ gene-YLR224W_S288C rna-NM_001182111.1_S288C cds-NP_013325.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000013.1:88977-90086:- gene-YLR224W_SA1 rna-NM_001182111.1_SA1 cds-NP_013325.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:571543-572652:+ gene-YLR224W_ThermosaccDry rna-NM_001182111.1_ThermosaccDry cds-NP_013325.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:582887-583996:+ gene-YLR224W_VR1 rna-NM_001182111.1_VR1 cds-NP_013325.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000024.1:95830-96939:+ gene-YLR224W_ZTW1 rna-NM_001182111.1_ZTW1 cds-NP_013325.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:557692-558801:+ gene-YLR224W_Sparadoxus rna-NM_001182111.1_Sparadoxus cds-NP_013325.1_Sparadoxus 90.9 99.9 Verified 1 1 1 False True False False False

Additional files