Gene name: UBX4
Reference locus (S288C): YMR067C
Gene biotype: protein_coding
Description: UBX domain-containing protein that interacts with Cdc48p; involved in degradation of polyubiquitinated proteins via the ERAD (ER-associated degradation) pathway; modulates the Cdc48p-Nplp-Ufd1p AAA ATPase complex during its role in delivery of misfolded proteins to the proteasome; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): CDC48 (0.999); UBX5 (0.983); AFG2 (0.981); SHP1 (0.976); NPL4 (0.946); UFD1 (0.937); UBX7 (0.931); UBX6 (0.929); UBX2 (0.907); UBX3 (0.873); DOA1 (0.862); UFD2 (0.851); RPO21 (0.847); VMS1 (0.817); AIM34 (0.745); UMP1 (0.723); RPT1 (0.718); DFM1 (0.701); UBP2 (0.683); PRE9 (0.68)
Homologues (species, bitscore): Gint3 (Drosophila melanogaster, 54.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:442035-443285:- | gene-YMR067C_AKU4011 | rna-NM_001182565.1_AKU4011 | cds-NP_013783.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:99498-100748:+ | gene-YMR067C_BG1 | rna-NM_001182565.1_BG1 | cds-NP_013783.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:384201-385451:- | gene-YMR067C_Bruggeman | rna-NM_001182565.1_Bruggeman | cds-NP_013783.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:384542-385792:- | gene-YMR067C_CAT1 | rna-NM_001182565.1_CAT1 | cds-NP_013783.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:374978-376228:- | gene-YMR067C_CBS1585 | rna-NM_001182565.1_CBS1585 | cds-NP_013783.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:380534-381784:- | gene-YMR067C_CBS436 | rna-NM_001182565.1_CBS436 | cds-NP_013783.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:488378-489628:- | gene-YMR067C_CBS6412 | rna-NM_001182565.1_CBS6412 | cds-NP_013783.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:374235-375485:- | gene-YMR067C_CBS6413 | rna-NM_001182565.1_CBS6413 | cds-NP_013783.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:398435-399685:- | gene-YMR067C_CENPK1137D | rna-NM_001182565.1_CENPK1137D | cds-NP_013783.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:374830-376080:- | gene-YMR067C_EthanolRed | rna-NM_001182565.1_EthanolRed | cds-NP_013783.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:377999-379249:- | gene-YMR067C_FaliES1 | rna-NM_001182565.1_FaliES1 | cds-NP_013783.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:57694-58944:+ | gene-YMR067C_JAY291 | rna-NM_001182565.1_JAY291 | cds-NP_013783.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:379944-381194:- | gene-YMR067C_MUCL30387 | rna-NM_001182565.1_MUCL30387 | cds-NP_013783.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:384614-385864:- | gene-YMR067C_MUCL30388 | rna-NM_001182565.1_MUCL30388 | cds-NP_013783.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:375266-376516:- | gene-YMR067C_MUCL39482 | rna-NM_001182565.1_MUCL39482 | cds-NP_013783.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:381922-383172:- | gene-YMR067C_MUCL42920 | rna-NM_001182565.1_MUCL42920 | cds-NP_013783.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:404277-405527:- | gene-YMR067C_NCIM3186 | rna-NM_001182565.1_NCIM3186 | cds-NP_013783.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:375178-376428:- | gene-YMR067C_NCYC1407 | rna-NM_001182565.1_NCYC1407 | cds-NP_013783.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:381131-382381:- | gene-YMR067C_PE2H3 | rna-NM_001182565.1_PE2H3 | cds-NP_013783.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:387226-388476:- | gene-YMR067C_PE2H4 | rna-NM_001182565.1_PE2H4 | cds-NP_013783.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:404323-405573:- | gene-YMR067C_S288C | rna-NM_001182565.1_S288C | cds-NP_013783.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:144574-145824:+ | gene-YMR067C_SA1 | rna-NM_001182565.1_SA1 | cds-NP_013783.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:375802-377052:- | gene-YMR067C_ThermosaccDry | rna-NM_001182565.1_ThermosaccDry | cds-NP_013783.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:387716-388966:- | gene-YMR067C_VR1 | rna-NM_001182565.1_VR1 | cds-NP_013783.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:354082-355332:- | gene-YMR067C_ZTW1 | rna-NM_001182565.1_ZTW1 | cds-NP_013783.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:387688-388941:- | gene-YMR067C_Sparadoxus | rna-NM_001182565.1_Sparadoxus | cds-NP_013783.1_Sparadoxus | 85.0 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |