Gene name: UBX2
Reference locus (S288C): YML013W
Gene biotype: protein_coding
Description: UBX domain-containing protein 2; Bridging factor involved in ER-associated protein degradation (ERAD); bridges the cytosolic Cdc48p-Npl1p-Ufd1p ATPase complex and the membrane associated Ssm4p and Hrd1p ubiquitin ligase complexes; contains a UBX (ubiquitin regulatory X) domain and a ubiquitin-associated (UBA) domain; redistributes from the ER to lipid droplets during the diauxic shift and stationary phase; required for the maintenance of lipid homeostasis
Top 10 interactors (score): UBC7 (0.999); YOS9 (0.999); HRD3 (0.999); CDC48 (0.999); SSM4 (0.999); USA1 (0.999); HRD1 (0.999); NPL4 (0.999); DER1 (0.999); UFD1 (0.999); CUE1 (0.991); DSC2 (0.986); SHP1 (0.985); UBX7 (0.97); DOA1 (0.93); DFM1 (0.923); FPR3 (0.918); UBX4 (0.907); OTU1 (0.882); VMS1 (0.865)
Homologues (species, bitscore): Faf (Drosophila melanogaster, 55.8); AT4G10790 (Arabidopsis thaliana, 51.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:293703-295457:+ | gene-YML013W_AKU4011 | rna-NM_001182371.1_AKU4011 | cds-NP_013699.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:247358-249112:- | gene-YML013W_BG1 | rna-NM_001182371.1_BG1 | cds-NP_013699.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:233683-235437:+ | gene-YML013W_Bruggeman | rna-NM_001182371.1_Bruggeman | cds-NP_013699.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:236193-237947:+ | gene-YML013W_CAT1 | rna-NM_001182371.1_CAT1 | cds-NP_013699.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:226681-228435:+ | gene-YML013W_CBS1585 | rna-NM_001182371.1_CBS1585 | cds-NP_013699.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:232208-233962:+ | gene-YML013W_CBS436 | rna-NM_001182371.1_CBS436 | cds-NP_013699.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:340414-342168:+ | gene-YML013W_CBS6412 | rna-NM_001182371.1_CBS6412 | cds-NP_013699.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:225936-227690:+ | gene-YML013W_CBS6413 | rna-NM_001182371.1_CBS6413 | cds-NP_013699.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:238880-240634:+ | gene-YML013W_CENPK1137D | rna-NM_001182371.1_CENPK1137D | cds-NP_013699.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:226715-228469:+ | gene-YML013W_EthanolRed | rna-NM_001182371.1_EthanolRed | cds-NP_013699.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:229681-231435:+ | gene-YML013W_FaliES1 | rna-NM_001182371.1_FaliES1 | cds-NP_013699.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:205493-207247:- | gene-YML013W_JAY291 | rna-NM_001182371.1_JAY291 | cds-NP_013699.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:231422-233176:+ | gene-YML013W_MUCL30387 | rna-NM_001182371.1_MUCL30387 | cds-NP_013699.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:236083-237837:+ | gene-YML013W_MUCL30388 | rna-NM_001182371.1_MUCL30388 | cds-NP_013699.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:226961-228715:+ | gene-YML013W_MUCL39482 | rna-NM_001182371.1_MUCL39482 | cds-NP_013699.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:232524-234278:+ | gene-YML013W_MUCL42920 | rna-NM_001182371.1_MUCL42920 | cds-NP_013699.1_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:244103-245857:+ | gene-YML013W_NCIM3186 | rna-NM_001182371.1_NCIM3186 | cds-NP_013699.1_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:226896-228650:+ | gene-YML013W_NCYC1407 | rna-NM_001182371.1_NCYC1407 | cds-NP_013699.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:232826-234580:+ | gene-YML013W_PE2H3 | rna-NM_001182371.1_PE2H3 | cds-NP_013699.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:238921-240675:+ | gene-YML013W_PE2H4 | rna-NM_001182371.1_PE2H4 | cds-NP_013699.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:244149-245903:+ | gene-YML013W_S288C | rna-NM_001182371.1_S288C | cds-NP_013699.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:292380-294134:- | gene-YML013W_SA1 | rna-NM_001182371.1_SA1 | cds-NP_013699.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:226743-228497:+ | gene-YML013W_ThermosaccDry | rna-NM_001182371.1_ThermosaccDry | cds-NP_013699.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:230715-232469:+ | gene-YML013W_VR1 | rna-NM_001182371.1_VR1 | cds-NP_013699.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:205802-207556:+ | gene-YML013W_ZTW1 | rna-NM_001182371.1_ZTW1 | cds-NP_013699.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:237471-239216:+ | gene-YML013W_Sparadoxus | rna-NM_001182371.1_Sparadoxus | cds-NP_013699.1_Sparadoxus | 88.3 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |