Gene name: UBR2
Reference locus (S288C): YLR024C
Gene biotype: protein_coding
Description: Cytoplasmic ubiquitin-protein ligase (E3); component of the Mub1p-Ubr2p-Rad6p ubiquitin ligase complex required for the ubiquitination and degradation of Rpn4p; mediates formation of the ternary complex
Top 10 interactors (score): RAD6 (0.999); MUB1 (0.991); ATE1 (0.971); RPN4 (0.935); RKR1 (0.915); UFD4 (0.911); HUL5 (0.909); DSN1 (0.904); SSM4 (0.856); SAN1 (0.845); UBC5 (0.827); TOM1 (0.819); BRE1 (0.804); UFD2 (0.777); UBC4 (0.757); UBR1 (0.722); PSH1 (0.716); CUP9 (0.705); SRY1 (0.696); UBP6 (0.693)
Homologues (species, bitscore): UBR2 (Homo sapiens, 119.8); Ubr2 (Mus musculus, 132.1); ubr2 (Danio rerio, 123.6); ubr2 (Xenopus tropicalis, 106.7); CG9086 (Drosophila melanogaster, 80.5); ubr-1 (Caenorhabditis elegans, 57.4); PRT6 (Arabidopsis thaliana, 57.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:175602-181220:- | gene-YLR024C_AKU4011 | rna-NM_001181911.2_AKU4011 | cds-NP_013124.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:138873-144491:- | gene-YLR024C_BG1 | rna-NM_001181911.2_BG1 | cds-NP_013124.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:185995-191613:- | gene-YLR024C_Bruggeman | rna-NM_001181911.2_Bruggeman | cds-NP_013124.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:186318-191936:- | gene-YLR024C_CAT1 | rna-NM_001181911.2_CAT1 | cds-NP_013124.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:183226-188844:- | gene-YLR024C_CBS1585 | rna-NM_001181911.2_CBS1585 | cds-NP_013124.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:173859-179477:- | gene-YLR024C_CBS436 | rna-NM_001181911.2_CBS436 | cds-NP_013124.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:181637-187255:- | gene-YLR024C_CBS6412 | rna-NM_001181911.2_CBS6412 | cds-NP_013124.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:183489-189107:- | gene-YLR024C_CBS6413 | rna-NM_001181911.2_CBS6413 | cds-NP_013124.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:172913-178531:- | gene-YLR024C_CENPK1137D | rna-NM_001181911.2_CENPK1137D | cds-NP_013124.1_CENPK1137D | 99.6 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:175613-181231:- | gene-YLR024C_EthanolRed | rna-NM_001181911.2_EthanolRed | cds-NP_013124.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:175183-180801:- | gene-YLR024C_FaliES1 | rna-NM_001181911.2_FaliES1 | cds-NP_013124.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000431.1:19377-24995:- | gene-YLR024C_JAY291 | rna-NM_001181911.2_JAY291 | cds-NP_013124.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:183344-188962:- | gene-YLR024C_MUCL30387 | rna-NM_001181911.2_MUCL30387 | cds-NP_013124.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:189966-195584:- | gene-YLR024C_MUCL30388 | rna-NM_001181911.2_MUCL30388 | cds-NP_013124.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:183721-189339:- | gene-YLR024C_MUCL39482 | rna-NM_001181911.2_MUCL39482 | cds-NP_013124.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:183623-189241:- | gene-YLR024C_MUCL42920 | rna-NM_001181911.2_MUCL42920 | cds-NP_013124.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:187637-193255:- | gene-YLR024C_NCIM3186 | rna-NM_001181911.2_NCIM3186 | cds-NP_013124.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:175341-180959:- | gene-YLR024C_NCYC1407 | rna-NM_001181911.2_NCYC1407 | cds-NP_013124.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:181656-187274:- | gene-YLR024C_PE2H3 | rna-NM_001181911.2_PE2H3 | cds-NP_013124.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:181397-187015:- | gene-YLR024C_PE2H4 | rna-NM_001181911.2_PE2H4 | cds-NP_013124.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:187663-193281:- | gene-YLR024C_S288C | rna-NM_001181911.2_S288C | cds-NP_013124.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000046.1:19512-25130:- | gene-YLR024C_SA1 | rna-NM_001181911.2_SA1 | cds-NP_013124.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:175688-181306:- | gene-YLR024C_ThermosaccDry | rna-NM_001181911.2_ThermosaccDry | cds-NP_013124.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:189105-194723:- | gene-YLR024C_VR1 | rna-NM_001181911.2_VR1 | cds-NP_013124.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:175051-180669:- | gene-YLR024C_ZTW1 | rna-NM_001181911.2_ZTW1 | cds-NP_013124.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:183841-189447:- | gene-YLR024C_Sparadoxus | rna-NM_001181911.2_Sparadoxus | cds-NP_013124.1_Sparadoxus | 89.4 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |