UBP8 (YMR223W)


Gene profile

Gene name: UBP8
Reference locus (S288C): YMR223W
Gene biotype: protein_coding

Description: Ubiquitin carboxyl-terminal hydrolase 8; Ubiquitin-specific protease component of the SAGA acetylation complex; required for SAGA (Spt-Ada-Gcn5-Acetyltransferase)-mediated deubiquitination of histone H2B

Top 10 interactors (score): HFI1 (0.999); NGG1 (0.999); ADA2 (0.999); SGF29 (0.999); SPT3 (0.999); TAF5 (0.999); TAF6 (0.999); SGF11 (0.999); SUS1 (0.999); SPT8 (0.999); GCN5 (0.999); SPT20 (0.999); TRA1 (0.999); SGF73 (0.999); TAF12 (0.999); SPT7 (0.999); TAF10 (0.998); TAF9 (0.998); UBI4 (0.997); HTB1 (0.987)

Homologues (species, bitscore): USP22 (Homo sapiens, 211.1); Usp22 (Mus musculus, 211.8); usp22 (Danio rerio, 202.2); usp22 (Xenopus tropicalis, 207.6); not (Drosophila melanogaster, 214.5); usp-3 (Caenorhabditis elegans, 136.3); UBP22 (Arabidopsis thaliana, 189.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:756622-758037:+ gene-YMR223W_AKU4011 rna-NM_001182730.1_AKU4011 cds-NP_013950.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:196571-197986:- gene-YMR223W_BG1 rna-NM_001182730.1_BG1 cds-NP_013950.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:700849-702264:+ gene-YMR223W_Bruggeman rna-NM_001182730.1_Bruggeman cds-NP_013950.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:704724-706139:+ gene-YMR223W_CAT1 rna-NM_001182730.1_CAT1 cds-NP_013950.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:688882-690297:+ gene-YMR223W_CBS1585 rna-NM_001182730.1_CBS1585 cds-NP_013950.1_CBS1585 99.9 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:693151-694566:+ gene-YMR223W_CBS436 rna-NM_001182730.1_CBS436 cds-NP_013950.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:800444-801859:+ gene-YMR223W_CBS6412 rna-NM_001182730.1_CBS6412 cds-NP_013950.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:688034-689449:+ gene-YMR223W_CBS6413 rna-NM_001182730.1_CBS6413 cds-NP_013950.1_CBS6413 99.9 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:711458-712873:+ gene-YMR223W_CENPK1137D rna-NM_001182730.1_CENPK1137D cds-NP_013950.1_CENPK1137D 99.9 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:749088-750503:+ gene-YMR223W_EthanolRed rna-NM_001182730.1_EthanolRed cds-NP_013950.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:694740-696155:+ gene-YMR223W_FaliES1 rna-NM_001182730.1_FaliES1 cds-NP_013950.1_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000141.1:89880-91295:- gene-YMR223W_JAY291 rna-NM_001182730.1_JAY291 cds-NP_013950.1_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:694632-696047:+ gene-YMR223W_MUCL30387 rna-NM_001182730.1_MUCL30387 cds-NP_013950.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:701860-703275:+ gene-YMR223W_MUCL30388 rna-NM_001182730.1_MUCL30388 cds-NP_013950.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:689952-691367:+ gene-YMR223W_MUCL39482 rna-NM_001182730.1_MUCL39482 cds-NP_013950.1_MUCL39482 99.9 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:697296-698711:+ gene-YMR223W_MUCL42920 rna-NM_001182730.1_MUCL42920 cds-NP_013950.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:716669-718084:+ gene-YMR223W_NCIM3186 rna-NM_001182730.1_NCIM3186 cds-NP_013950.1_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:689609-691024:+ gene-YMR223W_NCYC1407 rna-NM_001182730.1_NCYC1407 cds-NP_013950.1_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:699471-700886:+ gene-YMR223W_PE2H3 rna-NM_001182730.1_PE2H3 cds-NP_013950.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:700486-701901:+ gene-YMR223W_PE2H4 rna-NM_001182730.1_PE2H4 cds-NP_013950.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:716715-718130:+ gene-YMR223W_S288C rna-NM_001182730.1_S288C cds-NP_013950.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000002.1:89995-91410:- gene-YMR223W_SA1 rna-NM_001182730.1_SA1 cds-NP_013950.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:690911-692326:+ gene-YMR223W_ThermosaccDry rna-NM_001182730.1_ThermosaccDry cds-NP_013950.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:703994-705409:+ gene-YMR223W_VR1 rna-NM_001182730.1_VR1 cds-NP_013950.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000028.1:106616-108031:+ gene-YMR223W_ZTW1 rna-NM_001182730.1_ZTW1 cds-NP_013950.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:708865-710280:+ gene-YMR223W_Sparadoxus rna-NM_001182730.1_Sparadoxus cds-NP_013950.1_Sparadoxus 92.3 99.8 Verified 1 1 1 False True False False False

Additional files