Gene name: UBP2
Reference locus (S288C): YOR124C
Gene biotype: protein_coding
Description: Ubiquitin carboxyl-terminal hydrolase 2; Ubiquitin-specific protease; removes ubiquitin from ubiquitinated proteins; controls K63 homeostasis during oxidative stress; deubiquitinates Rsp5p and is required for MVB sorting of membrane proteins; can cleave polyubiquitin and has isopeptidase activity
Top 10 interactors (score): RSP5 (0.999); RUP1 (0.993); GUA1 (0.987); UBP12 (0.975); UBP3 (0.97); UFD4 (0.967); UBP14 (0.949); UBP15 (0.947); OTU2 (0.941); UBP6 (0.935); DOA4 (0.93); YUH1 (0.906); UBP1 (0.902); UBP9 (0.894); UBP7 (0.869); FZO1 (0.868); OTU1 (0.86); UBP8 (0.855); MDM30 (0.854); UBI4 (0.849)
Homologues (species, bitscore): USP28 (Homo sapiens, 80.5); Usp28 (Mus musculus, 78.2); usp28 (Danio rerio, 73.2); usp28 (Xenopus tropicalis, 77.0); Usp47 (Drosophila melanogaster, 52.4); K02C4.3 (Caenorhabditis elegans, 56.2); UBP6 (Arabidopsis thaliana, 54.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:538888-542706:- | gene-YOR124C_AKU4011 | rna-NM_001183543.3_AKU4011 | cds-NP_014767.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:36565-40383:+ | gene-YOR124C_BG1 | rna-NM_001183543.3_BG1 | cds-NP_014767.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:542436-546254:- | gene-YOR124C_Bruggeman | rna-NM_001183543.3_Bruggeman | cds-NP_014767.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:542441-546259:- | gene-YOR124C_CAT1 | rna-NM_001183543.3_CAT1 | cds-NP_014767.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:534450-538268:- | gene-YOR124C_CBS1585 | rna-NM_001183543.3_CBS1585 | cds-NP_014767.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:539161-542979:- | gene-YOR124C_CBS436 | rna-NM_001183543.3_CBS436 | cds-NP_014767.3_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:532936-536754:- | gene-YOR124C_CBS6412 | rna-NM_001183543.3_CBS6412 | cds-NP_014767.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:540232-544050:- | gene-YOR124C_CBS6413 | rna-NM_001183543.3_CBS6413 | cds-NP_014767.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:554901-558719:- | gene-YOR124C_CENPK1137D | rna-NM_001183543.3_CENPK1137D | cds-NP_014767.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:535256-539074:- | gene-YOR124C_EthanolRed | rna-NM_001183543.3_EthanolRed | cds-NP_014767.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:538952-542770:- | gene-YOR124C_FaliES1 | rna-NM_001183543.3_FaliES1 | cds-NP_014767.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000063.1:16496-20315:+ | gene-YOR124C_JAY291 | rna-NM_001183543.3_JAY291 | cds-NP_014767.3_JAY291 | 99.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:546994-550812:- | gene-YOR124C_MUCL30387 | rna-NM_001183543.3_MUCL30387 | cds-NP_014767.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:552201-556019:- | gene-YOR124C_MUCL30388 | rna-NM_001183543.3_MUCL30388 | cds-NP_014767.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:541845-545663:- | gene-YOR124C_MUCL39482 | rna-NM_001183543.3_MUCL39482 | cds-NP_014767.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:557890-561708:- | gene-YOR124C_MUCL42920 | rna-NM_001183543.3_MUCL42920 | cds-NP_014767.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:554713-558531:- | gene-YOR124C_NCIM3186 | rna-NM_001183543.3_NCIM3186 | cds-NP_014767.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:548292-552110:- | gene-YOR124C_NCYC1407 | rna-NM_001183543.3_NCYC1407 | cds-NP_014767.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:547295-551113:- | gene-YOR124C_PE2H3 | rna-NM_001183543.3_PE2H3 | cds-NP_014767.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:557672-561490:- | gene-YOR124C_PE2H4 | rna-NM_001183543.3_PE2H4 | cds-NP_014767.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:554824-558642:- | gene-YOR124C_S288C | rna-NM_001183543.3_S288C | cds-NP_014767.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000034.1:84363-88181:- | gene-YOR124C_SA1 | rna-NM_001183543.3_SA1 | cds-NP_014767.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:538135-541953:- | gene-YOR124C_ThermosaccDry | rna-NM_001183543.3_ThermosaccDry | cds-NP_014767.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:540240-544058:- | gene-YOR124C_VR1 | rna-NM_001183543.3_VR1 | cds-NP_014767.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:272071-275889:- | gene-YOR124C_ZTW1 | rna-NM_001183543.3_ZTW1 | cds-NP_014767.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:544092-547913:- | gene-YOR124C_Sparadoxus | rna-NM_001183543.3_Sparadoxus | cds-NP_014767.3_Sparadoxus | 88.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |