Gene name: UBP15
Reference locus (S288C): YMR304W
Gene biotype: protein_coding
Description: Ubiquitin carboxyl-terminal hydrolase 15; Ubiquitin-specific protease involved in protein deubiquitination; forms a complex with AAA peroxins Pex1p and Pex6p; deubiquitinates mono- and polyubiquitinated forms of Pex5p; deubiquitinates Clb5p, counteracting APC activity, and facilitating both Clb5p accumulation and S phase entry; physically interacts with anaphase-promoting complex/cyclosome (APC/C) activator, Cdh1p; catalytic activity regulated by an N-terminal TRAF-like domain and and C-terminal sequences; Belongs to the peptidase C19 family
Top 10 interactors (score): GUA1 (0.997); ECM30 (0.993); UBP14 (0.99); TEP1 (0.986); UBI4 (0.979); RPS31 (0.97); UFD4 (0.968); UBP2 (0.947); UBP3 (0.916); CRM1 (0.9); OTU2 (0.898); PEX5 (0.87); SYF1 (0.857); OTU1 (0.844); PEX6 (0.831); CDC53 (0.83); YUH1 (0.826); DOA4 (0.781); UBC13 (0.778); TFB2 (0.752)
Homologues (species, bitscore): USP7 (Homo sapiens, 464.2); Usp7 (Mus musculus, 467.6); usp7 (Danio rerio, 461.8); usp7 (Xenopus tropicalis, 441.0); Usp7 (Drosophila melanogaster, 373.2); math-33 (Caenorhabditis elegans, 329.3); UBP12 (Arabidopsis thaliana, 480.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:914533-918225:+ | gene-YMR304W_AKU4011 | rna-NM_001182814.1_AKU4011 | cds-NP_014033.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:35986-39678:- | gene-YMR304W_BG1 | rna-NM_001182814.1_BG1 | cds-NP_014033.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:859939-863631:+ | gene-YMR304W_Bruggeman | rna-NM_001182814.1_Bruggeman | cds-NP_014033.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:862523-866215:+ | gene-YMR304W_CAT1 | rna-NM_001182814.1_CAT1 | cds-NP_014033.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:846784-850476:+ | gene-YMR304W_CBS1585 | rna-NM_001182814.1_CBS1585 | cds-NP_014033.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:869096-872788:+ | gene-YMR304W_CBS436 | rna-NM_001182814.1_CBS436 | cds-NP_014033.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:957855-961547:+ | gene-YMR304W_CBS6412 | rna-NM_001182814.1_CBS6412 | cds-NP_014033.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:845902-849594:+ | gene-YMR304W_CBS6413 | rna-NM_001182814.1_CBS6413 | cds-NP_014033.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:869534-873226:+ | gene-YMR304W_CENPK1137D | rna-NM_001182814.1_CENPK1137D | cds-NP_014033.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:906716-910399:+ | gene-YMR304W_EthanolRed | rna-NM_001182814.1_EthanolRed | cds-NP_014033.1_EthanolRed | 99.2 | 99.7 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:852743-856435:+ | gene-YMR304W_FaliES1 | rna-NM_001182814.1_FaliES1 | cds-NP_014033.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000096.1:38527-42219:- | gene-YMR304W_JAY291 | rna-NM_001182814.1_JAY291 | cds-NP_014033.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:853069-856761:+ | gene-YMR304W_MUCL30387 | rna-NM_001182814.1_MUCL30387 | cds-NP_014033.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:862542-866234:+ | gene-YMR304W_MUCL30388 | rna-NM_001182814.1_MUCL30388 | cds-NP_014033.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:847849-851541:+ | gene-YMR304W_MUCL39482 | rna-NM_001182814.1_MUCL39482 | cds-NP_014033.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:856172-859864:+ | gene-YMR304W_MUCL42920 | rna-NM_001182814.1_MUCL42920 | cds-NP_014033.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:874941-878633:+ | gene-YMR304W_NCIM3186 | rna-NM_001182814.1_NCIM3186 | cds-NP_014033.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:847502-851194:+ | gene-YMR304W_NCYC1407 | rna-NM_001182814.1_NCYC1407 | cds-NP_014033.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:862818-866510:+ | gene-YMR304W_PE2H3 | rna-NM_001182814.1_PE2H3 | cds-NP_014033.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:858794-862486:+ | gene-YMR304W_PE2H4 | rna-NM_001182814.1_PE2H4 | cds-NP_014033.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:874987-878679:+ | gene-YMR304W_S288C | rna-NM_001182814.1_S288C | cds-NP_014033.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000036.1:52777-56469:+ | gene-YMR304W_SA1 | rna-NM_001182814.1_SA1 | cds-NP_014033.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:848911-852603:+ | gene-YMR304W_ThermosaccDry | rna-NM_001182814.1_ThermosaccDry | cds-NP_014033.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:862670-866362:+ | gene-YMR304W_VR1 | rna-NM_001182814.1_VR1 | cds-NP_014033.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:264152-267844:+ | gene-YMR304W_ZTW1 | rna-NM_001182814.1_ZTW1 | cds-NP_014033.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:867584-871276:+ | gene-YMR304W_Sparadoxus | rna-NM_001182814.1_Sparadoxus | cds-NP_014033.1_Sparadoxus | 90.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |