Gene name: UBP10
Reference locus (S288C): YNL186W
Gene biotype: protein_coding
Description: Ubiquitin carboxyl-terminal hydrolase 10; Ubiquitin-specific protease, deubiquitinates Ub-protein moieties; interacts with proteins that function in rRNA production and ribosome biogenesis via its intrinsically disordered regions; stabilizes Rpa190p by deubiquitination; controls PCNA deubiquitylation; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p, possibly other transporters; localized to the nucleolus; null mutant phenotypes are functionally complemented by human USP36
Top 10 interactors (score): HTB1 (0.959); SIR4 (0.954); UBP6 (0.942); BRE1 (0.905); HTB2 (0.898); UBP14 (0.885); RAD6 (0.866); SIR2 (0.862); UBP8 (0.858); DHR2 (0.81); SIR3 (0.78); UBP2 (0.778); DOT1 (0.762); UBP3 (0.755); MRPS5 (0.734); SET1 (0.719); LGE1 (0.715); UBP1 (0.693); PRP24 (0.671); RRI1 (0.651)
Homologues (species, bitscore): USP20 (Homo sapiens, 120.9); Usp20 (Mus musculus, 116.3); usp20 (Danio rerio, 122.1); usp20 (Xenopus tropicalis, 117.9); scny (Drosophila melanogaster, 126.3); usp-33 (Caenorhabditis elegans, 130.6); UBP23 (Arabidopsis thaliana, 126.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:283264-285618:+ | gene-YNL186W_AKU4011 | rna-NM_001183024.2_AKU4011 | cds-NP_014213.2_AKU4011 | 98.4 | 98.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:187217-189595:+ | gene-YNL186W_BG1 | rna-NM_001183024.2_BG1 | cds-NP_014213.2_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:293322-295652:+ | gene-YNL186W_Bruggeman | rna-NM_001183024.2_Bruggeman | cds-NP_014213.2_Bruggeman | 97.8 | 97.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:335568-337946:+ | gene-YNL186W_CAT1 | rna-NM_001183024.2_CAT1 | cds-NP_014213.2_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:283919-286261:+ | gene-YNL186W_CBS1585 | rna-NM_001183024.2_CBS1585 | cds-NP_014213.2_CBS1585 | 97.9 | 98.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:352206-354572:+ | gene-YNL186W_CBS436 | rna-NM_001183024.2_CBS436 | cds-NP_014213.2_CBS436 | 99.4 | 99.4 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:279321-281675:+ | gene-YNL186W_CBS6412 | rna-NM_001183024.2_CBS6412 | cds-NP_014213.2_CBS6412 | 98.4 | 98.9 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:280352-282694:+ | gene-YNL186W_CBS6413 | rna-NM_001183024.2_CBS6413 | cds-NP_014213.2_CBS6413 | 98.0 | 98.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:283326-285704:+ | gene-YNL186W_CENPK1137D | rna-NM_001183024.2_CENPK1137D | cds-NP_014213.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:280251-282593:+ | gene-YNL186W_EthanolRed | rna-NM_001183024.2_EthanolRed | cds-NP_014213.2_EthanolRed | 98.0 | 98.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:276164-278506:+ | gene-YNL186W_FaliES1 | rna-NM_001183024.2_FaliES1 | cds-NP_014213.2_FaliES1 | 98.0 | 98.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000260.1:40015-42393:- | gene-YNL186W_JAY291 | rna-NM_001183024.2_JAY291 | cds-NP_014213.2_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:289113-291467:+ | gene-YNL186W_MUCL30387 | rna-NM_001183024.2_MUCL30387 | cds-NP_014213.2_MUCL30387 | 98.9 | 98.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:323455-325785:+ | gene-YNL186W_MUCL30388 | rna-NM_001183024.2_MUCL30388 | cds-NP_014213.2_MUCL30388 | 97.7 | 97.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:281158-283500:+ | gene-YNL186W_MUCL39482 | rna-NM_001183024.2_MUCL39482 | cds-NP_014213.2_MUCL39482 | 97.9 | 98.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:283525-285891:+ | gene-YNL186W_MUCL42920 | rna-NM_001183024.2_MUCL42920 | cds-NP_014213.2_MUCL42920 | 99.4 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:289467-291845:+ | gene-YNL186W_NCIM3186 | rna-NM_001183024.2_NCIM3186 | cds-NP_014213.2_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:283252-285594:+ | gene-YNL186W_NCYC1407 | rna-NM_001183024.2_NCYC1407 | cds-NP_014213.2_NCYC1407 | 98.0 | 98.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:280161-282539:+ | gene-YNL186W_PE2H3 | rna-NM_001183024.2_PE2H3 | cds-NP_014213.2_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:279549-281927:+ | gene-YNL186W_PE2H4 | rna-NM_001183024.2_PE2H4 | cds-NP_014213.2_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:289498-291876:+ | gene-YNL186W_S288C | rna-NM_001183024.2_S288C | cds-NP_014213.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000018.1:121736-124102:- | gene-YNL186W_SA1 | rna-NM_001183024.2_SA1 | cds-NP_014213.2_SA1 | 99.4 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:277021-279363:+ | gene-YNL186W_ThermosaccDry | rna-NM_001183024.2_ThermosaccDry | cds-NP_014213.2_ThermosaccDry | 98.0 | 98.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:295485-297863:+ | gene-YNL186W_VR1 | rna-NM_001183024.2_VR1 | cds-NP_014213.2_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:186849-189190:+ | gene-YNL186W_ZTW1 | rna-NM_001183024.2_ZTW1 | cds-NP_014213.2_ZTW1 | 97.9 | 98.4 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:287537-289870:+ | gene-YNL186W_Sparadoxus | rna-NM_001183024.2_Sparadoxus | cds-NP_014213.2_Sparadoxus | 85.1 | 97.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |