UBI4 (YLL039C)


Gene profile

Gene name: UBI4
Reference locus (S288C): YLL039C
Gene biotype: protein_coding

Description: Polyubiquitin; Ubiquitin; becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): RPS31 (0.999); UBC1 (0.999); UBP6 (0.999); RPN10 (0.999); UBC13 (0.999); VPS27 (0.999); UBA1 (0.999); CDC48 (0.998); RAD23 (0.998); RPL40A (0.998); YUH1 (0.998); UBP8 (0.997); RPN11 (0.997); DSK2 (0.996); RSP5 (0.996); MMS2 (0.995); DOA1 (0.994); RPN1 (0.994); STP22 (0.994); CDC34 (0.994)

Homologues (species, bitscore): UBC (Homo sapiens, 725.7); Ubc (Mus musculus, 726.5); UBC (Danio rerio, 725.7); ubb (Xenopus tropicalis, 719.5); Ubi-p63E (Drosophila melanogaster, 726.1); ubq-1 (Caenorhabditis elegans, 733.4); UBQ4 (Arabidopsis thaliana, 740.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:51217-52362:- gene-YLL039C_AKU4011 rna-NM_001181859.1_AKU4011 cds-NP_013061.1_AKU4011 98.4 99.8 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:15158-16303:- gene-YLL039C_BG1 rna-NM_001181859.1_BG1 cds-NP_013061.1_BG1 98.4 99.8 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:61113-62363:- gene-YLL039C_Bruggeman rna-NM_001181859.1_Bruggeman cds-NP_013061.1_Bruggeman 86.9 99.8 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:62096-63241:- gene-YLL039C_CAT1 rna-NM_001181859.1_CAT1 cds-NP_013061.1_CAT1 98.4 99.8 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia MBVS01000008.1:1-914:+ gene-YLL039C_CBS1585 rna-NM_001181859.1_CBS1585 cds-NP_013061.1_CBS1585 78.0 79.7 Mismatch 1 1 0 False False False True False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:49117-50262:- gene-YLL039C_CBS436 rna-NM_001181859.1_CBS436 cds-NP_013061.1_CBS436 99.4 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:58787-59932:- gene-YLL039C_CBS6412 rna-NM_001181859.1_CBS6412 cds-NP_013061.1_CBS6412 98.4 99.8 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:58913-60058:- gene-YLL039C_CBS6413 rna-NM_001181859.1_CBS6413 cds-NP_013061.1_CBS6413 98.4 99.8 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:49042-50214:- gene-YLL039C_CENPK1137D rna-NM_001181859.1_CENPK1137D cds-NP_013061.1_CENPK1137D 84.0 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:51842-52927:- gene-YLL039C_EthanolRed rna-NM_001181859.1_EthanolRed cds-NP_013061.1_EthanolRed 86.0 93.5 Unannotated 1 1 0 False False True False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:51155-52240:- gene-YLL039C_FaliES1 rna-NM_001181859.1_FaliES1 cds-NP_013061.1_FaliES1 86.0 93.5 Unannotated 1 1 0 False False True False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000145.1:16163-16572:- gene-YLL039C_JAY291 rna-NM_001181859.1_JAY291 cds-NP_013061.1_JAY291 35.6 35.7 Mismatch 1 1 0 False False True False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:58870-60024:- gene-YLL039C_MUCL30387 rna-NM_001181859.1_MUCL30387 cds-NP_013061.1_MUCL30387 88.7 98.9 Verified 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:63082-64748:- gene-YLL039C_MUCL30388 rna-NM_001181859.1_MUCL30388 cds-NP_013061.1_MUCL30388 67.3 99.8 Unannotated 1 1 0 False False False True False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:59126-60271:- gene-YLL039C_MUCL39482 rna-NM_001181859.1_MUCL39482 cds-NP_013061.1_MUCL39482 95.3 99.6 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe MBVV01000228.1:68-765:- gene-YLL039C_MUCL42920 rna-NM_001181859.1_MUCL42920 cds-NP_013061.1_MUCL42920 59.2 60.9 Mismatch 1 1 0 False False True False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:64036-65181:- gene-YLL039C_NCIM3186 rna-NM_001181859.1_NCIM3186 cds-NP_013061.1_NCIM3186 98.6 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:50992-52137:- gene-YLL039C_NCYC1407 rna-NM_001181859.1_NCYC1407 cds-NP_013061.1_NCYC1407 98.4 99.8 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:57679-58824:- gene-YLL039C_PE2H3 rna-NM_001181859.1_PE2H3 cds-NP_013061.1_PE2H3 98.4 99.8 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:57485-58630:- gene-YLL039C_PE2H4 rna-NM_001181859.1_PE2H4 cds-NP_013061.1_PE2H4 98.5 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:64062-65207:- gene-YLL039C_S288C rna-NM_001181859.1_S288C cds-NP_013061.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000047.1:57353-58726:- gene-YLL039C_SA1 rna-NM_001181859.1_SA1 cds-NP_013061.1_SA1 81.2 99.6 Mismatch 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:51661-52746:- gene-YLL039C_ThermosaccDry rna-NM_001181859.1_ThermosaccDry cds-NP_013061.1_ThermosaccDry 86.0 93.5 Unannotated 1 1 0 False False True False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:65254-66399:- gene-YLL039C_VR1 rna-NM_001181859.1_VR1 cds-NP_013061.1_VR1 99.2 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:50985-52130:- gene-YLL039C_ZTW1 rna-NM_001181859.1_ZTW1 cds-NP_013061.1_ZTW1 98.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:59608-60753:- gene-YLL039C_Sparadoxus rna-NM_001181859.1_Sparadoxus cds-NP_013061.1_Sparadoxus 87.9 99.6 Verified 1 1 1 True True False False False

Additional files