UBC8 (YEL012W)


Gene profile

Gene name: UBC8
Reference locus (S288C): YEL012W
Gene biotype: protein_coding

Description: Ubiquitin-conjugating enzyme that regulates gluconeogenesis; negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro

Top 10 interactors (score): UBA1 (0.912); RMD5 (0.877); VID28 (0.869); VID30 (0.834); FYV10 (0.824); ATG8 (0.814); GID8 (0.786); VID24 (0.778); CCT8 (0.755); FBP1 (0.75); UBI4 (0.749); PSH1 (0.739); PRE9 (0.705); RAD1 (0.7); UBA3 (0.691); MMS2 (0.688); YLR345W (0.675); UGX2 (0.669); UBP6 (0.665); GGA1 (0.657)

Homologues (species, bitscore): UBE2H (Homo sapiens, 200.3); Ube2h (Mus musculus, 200.3); ube2h (Danio rerio, 199.1); ube2h (Xenopus tropicalis, 196.8); UbcE2H (Drosophila melanogaster, 192.6); ubc-8 (Caenorhabditis elegans, 186.8); UBC5 (Arabidopsis thaliana, 214.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:125799-126578:+ gene-YEL012W_AKU4011 rna-NM_001178827.1_AKU4011 cds-NP_010904.2_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:299389-300168:- gene-YEL012W_BG1 rna-NM_001178827.1_BG1 cds-NP_010904.2_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:132326-133105:+ gene-YEL012W_Bruggeman rna-NM_001178827.1_Bruggeman cds-NP_010904.2_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:127975-128754:+ gene-YEL012W_CAT1 rna-NM_001178827.1_CAT1 cds-NP_010904.2_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:126085-126864:+ gene-YEL012W_CBS1585 rna-NM_001178827.1_CBS1585 cds-NP_010904.2_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:127377-128156:+ gene-YEL012W_CBS436 rna-NM_001178827.1_CBS436 cds-NP_010904.2_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:126018-126797:+ gene-YEL012W_CBS6412 rna-NM_001178827.1_CBS6412 cds-NP_010904.2_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:130625-131404:+ gene-YEL012W_CBS6413 rna-NM_001178827.1_CBS6413 cds-NP_010904.2_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:129627-130406:+ gene-YEL012W_CENPK1137D rna-NM_001178827.1_CENPK1137D cds-NP_010904.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:126464-127243:+ gene-YEL012W_EthanolRed rna-NM_001178827.1_EthanolRed cds-NP_010904.2_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:126723-127502:+ gene-YEL012W_FaliES1 rna-NM_001178827.1_FaliES1 cds-NP_010904.2_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000398.1:45266-46045:+ gene-YEL012W_JAY291 rna-NM_001178827.1_JAY291 cds-NP_010904.2_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:130046-130825:+ gene-YEL012W_MUCL30387 rna-NM_001178827.1_MUCL30387 cds-NP_010904.2_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:126014-126793:+ gene-YEL012W_MUCL30388 rna-NM_001178827.1_MUCL30388 cds-NP_010904.2_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:125102-125881:+ gene-YEL012W_MUCL39482 rna-NM_001178827.1_MUCL39482 cds-NP_010904.2_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:129732-130511:+ gene-YEL012W_MUCL42920 rna-NM_001178827.1_MUCL42920 cds-NP_010904.2_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:131771-132550:+ gene-YEL012W_NCIM3186 rna-NM_001178827.1_NCIM3186 cds-NP_010904.2_NCIM3186 99.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:130208-130987:+ gene-YEL012W_NCYC1407 rna-NM_001178827.1_NCYC1407 cds-NP_010904.2_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:134233-135012:+ gene-YEL012W_PE2H3 rna-NM_001178827.1_PE2H3 cds-NP_010904.2_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:130148-130927:+ gene-YEL012W_PE2H4 rna-NM_001178827.1_PE2H4 cds-NP_010904.2_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:131772-132551:+ gene-YEL012W_S288C rna-NM_001178827.1_S288C cds-NP_010904.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000020.1:110676-111455:- gene-YEL012W_SA1 rna-NM_001178827.1_SA1 cds-NP_010904.2_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:127128-127907:+ gene-YEL012W_ThermosaccDry rna-NM_001178827.1_ThermosaccDry cds-NP_010904.2_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:126324-127103:+ gene-YEL012W_VR1 rna-NM_001178827.1_VR1 cds-NP_010904.2_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:125142-125921:+ gene-YEL012W_ZTW1 rna-NM_001178827.1_ZTW1 cds-NP_010904.2_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:128747-129526:+ gene-YEL012W_Sparadoxus rna-NM_001178827.1_Sparadoxus cds-NP_010904.2_Sparadoxus 93.4 100.0 Unannotated 1 1 0 False False False False True

Additional files