Gene name: UBC5
Reference locus (S288C): YDR059C
Gene biotype: protein_coding
Description: Ubiquitin-conjugating enzyme; mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible; protein abundance increases in response to DNA replication stress; UBC5 has a paralog, UBC4, that arose from the whole genome duplication
Top 10 interactors (score): UBA1 (0.997); APC11 (0.992); RSP5 (0.987); UBI4 (0.983); UBC4 (0.982); HRT1 (0.981); MMS2 (0.98); MOT2 (0.979); UBC1 (0.978); UBC9 (0.965); UFD4 (0.921); CDC53 (0.895); CUL3 (0.853); SMT3 (0.852); RPS31 (0.842); UBR2 (0.827); ELC1 (0.78); BIR1 (0.771); SLX5 (0.756); TOM1 (0.742)
Homologues (species, bitscore): UBE2D2 (Homo sapiens, 256.5); Ube2d2a (Mus musculus, 256.5); ube2d2l (Danio rerio, 258.5); ube2d3 (Xenopus tropicalis, 256.5); eff (Drosophila melanogaster, 258.5); let-70 (Caenorhabditis elegans, 256.5); UBC30 (Arabidopsis thaliana, 251.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:546776-547312:- | gene-YDR059C_AKU4011 | rna-NM_001180367.1_AKU4011 | cds-NP_010344.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:579724-580261:+ | gene-YDR059C_BG1 | rna-NM_001180367.1_BG1 | cds-NP_010344.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:579083-579619:- | gene-YDR059C_Bruggeman | rna-NM_001180367.1_Bruggeman | cds-NP_010344.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:562116-562652:- | gene-YDR059C_CAT1 | rna-NM_001180367.1_CAT1 | cds-NP_010344.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:537730-538266:- | gene-YDR059C_CBS1585 | rna-NM_001180367.1_CBS1585 | cds-NP_010344.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:562897-563433:- | gene-YDR059C_CBS436 | rna-NM_001180367.1_CBS436 | cds-NP_010344.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:534142-534678:- | gene-YDR059C_CBS6412 | rna-NM_001180367.1_CBS6412 | cds-NP_010344.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:562811-563347:- | gene-YDR059C_CBS6413 | rna-NM_001180367.1_CBS6413 | cds-NP_010344.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:568200-568736:- | gene-YDR059C_CENPK1137D | rna-NM_001180367.1_CENPK1137D | cds-NP_010344.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:548594-549130:- | gene-YDR059C_EthanolRed | rna-NM_001180367.1_EthanolRed | cds-NP_010344.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:555040-555576:- | gene-YDR059C_FaliES1 | rna-NM_001180367.1_FaliES1 | cds-NP_010344.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000358.1:75229-75765:+ | gene-YDR059C_JAY291 | rna-NM_001180367.1_JAY291 | cds-NP_010344.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:563776-564312:- | gene-YDR059C_MUCL30387 | rna-NM_001180367.1_MUCL30387 | cds-NP_010344.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:554166-554702:- | gene-YDR059C_MUCL30388 | rna-NM_001180367.1_MUCL30388 | cds-NP_010344.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:539101-539637:- | gene-YDR059C_MUCL39482 | rna-NM_001180367.1_MUCL39482 | cds-NP_010344.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:469576-470112:- | gene-YDR059C_MUCL42920 | rna-NM_001180367.1_MUCL42920 | cds-NP_010344.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:569157-569693:- | gene-YDR059C_NCIM3186 | rna-NM_001180367.1_NCIM3186 | cds-NP_010344.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:538035-538571:- | gene-YDR059C_NCYC1407 | rna-NM_001180367.1_NCYC1407 | cds-NP_010344.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:557674-558210:- | gene-YDR059C_PE2H3 | rna-NM_001180367.1_PE2H3 | cds-NP_010344.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:556979-557515:- | gene-YDR059C_PE2H4 | rna-NM_001180367.1_PE2H4 | cds-NP_010344.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:569234-569770:- | gene-YDR059C_S288C | rna-NM_001180367.1_S288C | cds-NP_010344.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:75721-76257:+ | gene-YDR059C_SA1 | rna-NM_001180367.1_SA1 | cds-NP_010344.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:554733-555269:- | gene-YDR059C_ThermosaccDry | rna-NM_001180367.1_ThermosaccDry | cds-NP_010344.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:567488-568024:- | gene-YDR059C_VR1 | rna-NM_001180367.1_VR1 | cds-NP_010344.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:552385-552921:- | gene-YDR059C_ZTW1 | rna-NM_001180367.1_ZTW1 | cds-NP_010344.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:556881-557418:- | gene-YDR059C_Sparadoxus | rna-NM_001180367.1_Sparadoxus | cds-NP_010344.1_Sparadoxus | 92.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |