Gene name: UBC1
Reference locus (S288C): YDR177W
Gene biotype: protein_coding
Description: Ubiquitin-conjugating enzyme; key E2 partner with Ubc4p for the anaphase-promoting complex (APC); mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response; protein abundance increases in response to DNA replication stress key E2 partner with Ubc4p for the anaphase-promoting complex (APC)
Top 10 interactors (score): UBI4 (0.999); UBA1 (0.999); UBC4 (0.997); APC11 (0.996); MMS2 (0.995); RPS31 (0.993); RSP5 (0.987); UBC9 (0.979); UBC5 (0.978); RPL40B (0.968); HRD1 (0.948); RPN11 (0.932); RPL40A (0.932); HRT1 (0.914); BCY1 (0.897); UFD4 (0.896); SKP1 (0.835); HUL5 (0.833); CDC48 (0.831); SSM4 (0.822)
Homologues (species, bitscore): UBE2K (Homo sapiens, 163.7); Ube2k (Mus musculus, 163.7); ube2kb (Danio rerio, 165.6); ube2d4 (Xenopus tropicalis, 143.7); Ubc4 (Drosophila melanogaster, 158.7); ubc-21 (Caenorhabditis elegans, 155.6); UBC27 (Arabidopsis thaliana, 161.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:785404-786051:+ | gene-YDR177W_AKU4011 | rna-NM_001180484.3_AKU4011 | cds-NP_010462.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:339746-340393:- | gene-YDR177W_BG1 | rna-NM_001180484.3_BG1 | cds-NP_010462.3_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:817829-818476:+ | gene-YDR177W_Bruggeman | rna-NM_001180484.3_Bruggeman | cds-NP_010462.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:805074-805721:+ | gene-YDR177W_CAT1 | rna-NM_001180484.3_CAT1 | cds-NP_010462.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:775771-776418:+ | gene-YDR177W_CBS1585 | rna-NM_001180484.3_CBS1585 | cds-NP_010462.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:804755-805402:+ | gene-YDR177W_CBS436 | rna-NM_001180484.3_CBS436 | cds-NP_010462.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:772576-773223:+ | gene-YDR177W_CBS6412 | rna-NM_001180484.3_CBS6412 | cds-NP_010462.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:803119-803766:+ | gene-YDR177W_CBS6413 | rna-NM_001180484.3_CBS6413 | cds-NP_010462.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:815686-816333:+ | gene-YDR177W_CENPK1137D | rna-NM_001180484.3_CENPK1137D | cds-NP_010462.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:786173-786820:+ | gene-YDR177W_EthanolRed | rna-NM_001180484.3_EthanolRed | cds-NP_010462.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:794385-795032:+ | gene-YDR177W_FaliES1 | rna-NM_001180484.3_FaliES1 | cds-NP_010462.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000068.1:54330-54977:- | gene-YDR177W_JAY291 | rna-NM_001180484.3_JAY291 | cds-NP_010462.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:803475-804122:+ | gene-YDR177W_MUCL30387 | rna-NM_001180484.3_MUCL30387 | cds-NP_010462.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:791717-792364:+ | gene-YDR177W_MUCL30388 | rna-NM_001180484.3_MUCL30388 | cds-NP_010462.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:777218-777865:+ | gene-YDR177W_MUCL39482 | rna-NM_001180484.3_MUCL39482 | cds-NP_010462.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:715917-716564:+ | gene-YDR177W_MUCL42920 | rna-NM_001180484.3_MUCL42920 | cds-NP_010462.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:816801-817448:+ | gene-YDR177W_NCIM3186 | rna-NM_001180484.3_NCIM3186 | cds-NP_010462.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:780351-780998:+ | gene-YDR177W_NCYC1407 | rna-NM_001180484.3_NCYC1407 | cds-NP_010462.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:797079-797726:+ | gene-YDR177W_PE2H3 | rna-NM_001180484.3_PE2H3 | cds-NP_010462.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:796384-797031:+ | gene-YDR177W_PE2H4 | rna-NM_001180484.3_PE2H4 | cds-NP_010462.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:816878-817525:+ | gene-YDR177W_S288C | rna-NM_001180484.3_S288C | cds-NP_010462.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:162590-163237:+ | gene-YDR177W_SA1 | rna-NM_001180484.3_SA1 | cds-NP_010462.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:792540-793187:+ | gene-YDR177W_ThermosaccDry | rna-NM_001180484.3_ThermosaccDry | cds-NP_010462.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:807769-808416:+ | gene-YDR177W_VR1 | rna-NM_001180484.3_VR1 | cds-NP_010462.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:55253-55900:+ | gene-YDR177W_ZTW1 | rna-NM_001180484.3_ZTW1 | cds-NP_010462.3_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:797666-798313:+ | gene-YDR177W_Sparadoxus | rna-NM_001180484.3_Sparadoxus | cds-NP_010462.3_Sparadoxus | 92.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |